Mastering global challenges such as the 2020 Coronavirus pandemic requires implementing effective responses at various social levels. Leadership teams (governmental, industrial) need to integrate available information to introduce effective regulation and update their decisions as new information becomes available. Groups (families, peers, teams) need to act persistently, even when these actions oppose members’ individual short-term interests. Moreover, individuals need to stay calm and act diligently, while dealing with emotions of threat and resisting counterproductive social influence. Our research programme on implementation intentions at social levels suggests that collective if-then plans facilitate goal attainment for teams, groups, and individuals in social contexts. We therefore analyse how if-then planning can help master global human challenges such as the 2020 Coronavirus pandemic.