In vitro corrosion and cytocompatibility properties of Mg-2Gd-X(Ag, Ca) alloys
Publikation: Beiträge in Sammelwerken › Aufsätze in Konferenzbänden › Forschung › begutachtet
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In vitro corrosion and cytocompatibility properties of Mg-2Gd-X(Ag, Ca) alloys. / Lu, Yiyi; Huang, Yuanding; Feyerabend, Frank et al.
Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition. Hrsg. / Alok Singh; Kiran Solanki; Michele Viola Manuel; Neale R. Neelameggham. The Minerals, Metals & Materials Society, 2016. S. 347-351 (Magnesium Technology; Band 2016-January).Publikation: Beiträge in Sammelwerken › Aufsätze in Konferenzbänden › Forschung › begutachtet
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TY - CHAP
T1 - In vitro corrosion and cytocompatibility properties of Mg-2Gd-X(Ag, Ca) alloys
AU - Lu, Yiyi
AU - Huang, Yuanding
AU - Feyerabend, Frank
AU - Willumeit-Römer, Regine
AU - Kainer, Karl Urich
AU - Hort, Norbert
N1 - Conference code: 145
PY - 2016
Y1 - 2016
N2 - The effects of solution treatment (T4) on the in vitro corrosion properties were investigated for Mg-2Gd-xAg (x=l, 2 wt. %), Mg-2Gd-xCa (x=0.4, 0.8 wt. %) alloys. The cytocompatibility of pure Mg, Mg-2Gd, Mg-2Gd-2Ag and Mg-2Gd-0.8Ca alloy was studied as well. All alloys were prepared by permanent mould casting. T4 heat treatment was carried out at 510 °C for 48 h under Ar atmosphere and specimens were quenched in water at room temperature. Corrosion experiments were performed in cell culture medium under cell culture conditions. Cytocompatibility was evaluated by direct cell adhesion and live/dead staining tests. After T4 heat treatment, the amount of intermetallic phases is significantly decreased, which leads to significant improvement of corrosion properties by a very high factor (5-30). The results of live/dead staining reveal that the cells are mostly in viable state and homogenously distributed over the surface. The corrosion layer shows no cytotoxicity to primary human osteoblasts.
AB - The effects of solution treatment (T4) on the in vitro corrosion properties were investigated for Mg-2Gd-xAg (x=l, 2 wt. %), Mg-2Gd-xCa (x=0.4, 0.8 wt. %) alloys. The cytocompatibility of pure Mg, Mg-2Gd, Mg-2Gd-2Ag and Mg-2Gd-0.8Ca alloy was studied as well. All alloys were prepared by permanent mould casting. T4 heat treatment was carried out at 510 °C for 48 h under Ar atmosphere and specimens were quenched in water at room temperature. Corrosion experiments were performed in cell culture medium under cell culture conditions. Cytocompatibility was evaluated by direct cell adhesion and live/dead staining tests. After T4 heat treatment, the amount of intermetallic phases is significantly decreased, which leads to significant improvement of corrosion properties by a very high factor (5-30). The results of live/dead staining reveal that the cells are mostly in viable state and homogenously distributed over the surface. The corrosion layer shows no cytotoxicity to primary human osteoblasts.
KW - Ca) alloys
KW - Cytocompatibility
KW - In vitro corrosion
KW - Mg-2Gd-x(Ag
KW - Solution treatment (T4)
KW - Engineering
UR - http://www.scopus.com/inward/record.url?scp=84975058748&partnerID=8YFLogxK
U2 - 10.1002/9781119274803.ch67
DO - 10.1002/9781119274803.ch67
M3 - Article in conference proceedings
AN - SCOPUS:84975058748
T3 - Magnesium Technology
SP - 347
EP - 351
BT - Magnesium Technology 2016 - Held During TMS 2016
A2 - Singh, Alok
A2 - Solanki, Kiran
A2 - Manuel, Michele Viola
A2 - Neelameggham, Neale R.
PB - The Minerals, Metals & Materials Society
T2 - 145th Annual Meeting and Exhibition of Magnesium Technology - TMS 2016
Y2 - 14 February 2016 through 18 February 2016
ER -