TY - JOUR

T1 - Fragrance allergens in household detergents

AU - Wieck, Stefanie

AU - Olsson, Oliver

AU - Kümmerer, Klaus

AU - Klaschka, Ursula

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Consumers are confronted with a large number of fragrance allergens from various sources. Until now, the discussion of exposure sources has mainly addressed cosmetic products and neglected other scented products in households. For the first time, fragrance allergens were evaluated in a complete set of detergents in households. In 131 households, we investigated the prevalence of detergents and searched their lists of ingredients for 26 fragrance allergens liable to be indicated on products according to the European Detergents Regulations. On the ingredient lists of 1447 products, these 26 fragrance substances were named almost 2000 times, most often limonene, linalool and hexyl cinnamal. Benzyl salicylate was used frequently in all-purpose cleaners. Linalool and limonene, hexyl cinnamal and butylphenyl methylpropional and citronellol and linalool co-occurred most often together in products. Fragrance allergens co-occurring together most frequently within households were eugenol, coumarin and cinnamyl alcohol. The study shows that detergents could play a relevant role for the exposure of consumers towards fragrance allergens and that they should not be underestimated as an exposure source during the exposure assessment.

AB - Consumers are confronted with a large number of fragrance allergens from various sources. Until now, the discussion of exposure sources has mainly addressed cosmetic products and neglected other scented products in households. For the first time, fragrance allergens were evaluated in a complete set of detergents in households. In 131 households, we investigated the prevalence of detergents and searched their lists of ingredients for 26 fragrance allergens liable to be indicated on products according to the European Detergents Regulations. On the ingredient lists of 1447 products, these 26 fragrance substances were named almost 2000 times, most often limonene, linalool and hexyl cinnamal. Benzyl salicylate was used frequently in all-purpose cleaners. Linalool and limonene, hexyl cinnamal and butylphenyl methylpropional and citronellol and linalool co-occurred most often together in products. Fragrance allergens co-occurring together most frequently within households were eugenol, coumarin and cinnamyl alcohol. The study shows that detergents could play a relevant role for the exposure of consumers towards fragrance allergens and that they should not be underestimated as an exposure source during the exposure assessment.

KW - Aggregated exposure

KW - Co-exposure

KW - Contact allergy

KW - Detergents

KW - Fragrance allergens

KW - Product inventory

KW - Washing and cleaning agents

KW - Chemistry

UR - http://www.scopus.com/inward/record.url?scp=85049118619&partnerID=8YFLogxK

U2 - 10.1016/j.yrtph.2018.06.015

DO - 10.1016/j.yrtph.2018.06.015

M3 - Journal articles

C2 - 29940212

AN - SCOPUS:85049118619

VL - 97

SP - 163

EP - 169

JO - Regulatory toxicology and pharmacology : RTP

JF - Regulatory toxicology and pharmacology : RTP

SN - 0273-2300

ER -