A scale-up procedure to dialkyl carbonates; evaluation of their properties, biodegradability, and toxicity

Research output: Journal contributionsJournal articlesResearchpeer-review

Authors

In this work, we explored a scale-up procedure to non-commercially available or expensive dialkyl carbonates via transcarbonylation reaction of an alcohol with dimethyl carbonate promoted by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). DACs selected for this study include symmetrical and unsymmetrical compounds incorporating alkyl, alkoxyalkyl, aminoalkyl, and thioalkyl moieties. Compared to previously published works, the proposed procedure was customized for large-scale production of DACs (up to 100 mL); purification of the products was achieved by distillation, and recycling of the exceeding reagents was addressed. Furthermore, the role of the catalyst was investigated, and a possible reaction mechanism proposed. The chemical-physical properties of the new DACs were evaluated employing softwares and models based on quantitative structure-activity relationships (QSAR). Biodegradability and toxicity tests have also been carried out both experimentally and by computational studies so to investigate the effect of the sulfur, nitrogen, or oxygen-containing moieties on the greenness of these – in some cases new –solvents and reagents.
Original languageEnglish
Article number100639
JournalSustainable Chemistry and Pharmacy
Volume26
ISSN2352-5541
DOIs
Publication statusPublished - 01.05.2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier B.V.

    Research areas

  • Chemistry - carbonates, Preparative-scale synthesis, Organic catalyst, Green chemistry, reaction mechanism, diakyl carbonates
  • Sustainability Science - Toxicity

Recently viewed

Activities

  1. Are Self-Employed Time and Money Poor? Dynamics of Interpendent Multidimensional Poverty with German Time Use Diary Data
  2. Istron-Tagung 2008
  3. IMISCOE (Verlag)
  4. Internes Anti-Rassismus-Training
  5. HOW SUSTAINABILITY ACCOUNTING CONTRIBUTES TO IMPROVED INFORMATION MANAGEMENT AND MANAGEMENT CONTROL
  6. The relationship between intragenerational and intergenerational justice in the use of ecosystems and their services. An ecological-economic mode.
  7. Sonic Spaces and Playfulness
  8. The relationship between intragenerational and intergenerational justice in the use of ecosystems and their services
  9. Investigating the relationship between teachers' acceptance and use of educational technology and student data
  10. Processes of Sustainability Transformation. An inter- and transdisciplinary project
  11. Empathic Healthcare Chatbots: Comparing the Effects of Emotional Expression and Caring Behavior
  12. Kunstuniversität Linz
  13. Aesthetics of complexity, artists and resilient communities in urban anthropo-scenes
  14. From the Environmental State to the Sustainability State? Conceptualization, Indicators, and Examples
  15. 2nd Interdisciplinary Insights on Fraud and Corruption - I2FC 2014
  16. Universität von St. Andrews
  17. Der "als-ob" Modus: Polizei, Protest, Staatlichkeit
  18. Experimente in den Sozialwissenschaften: Methodenkurs
  19. Stimmtraining - 2009
  20. From Traditional Games to Digital Games: Predigital Precursors of Gamification
  21. “Relying on Spontaneity”
  22. Student Gender and Teachers' Grading and Written Feedback on Math or Language Assignments
  23. New Energy for a Better World
  24. Modern Language Association (Externe Organisation)
  25. Netzwerk Migrationsrecht (Externe Organisation)
  26. “Research Methods and Methodologies”
  27. Workshop Open Educational Ressourcen für das Sprachenlernen