The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients: Results of a randomized controlled trial

Research output: Journal contributionsJournal articlesResearchpeer-review

Standard

The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients: Results of a randomized controlled trial. / Kok, Gemma; Burger, Huibert; Riper, Heleen et al.
In: Psychotherapy and Psychosomatics, Vol. 84, No. 2, 2015, p. 90-99.

Research output: Journal contributionsJournal articlesResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{2bd021972bca49db9c1e5c630145bc5d,
title = "The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients: Results of a randomized controlled trial",
abstract = "Background: Internet-based cognitive therapy with monitoring via text messages (mobile CT), in addition to treatment as usual (TAU), might offer a cost-effective way to treat recurrent depression. Method: Remitted patients with at least 2 previous episodes of depression were randomized to mobile CT in addition to TAU (n = 126) or TAU only (n = 113). A linear mixed model was used to examine the effect of the treatment condition on a 3-month course of depressive symptoms after remission. Both an intention-to-treat analysis (n = 239) and a completer analysis (n = 193) were used. Depressive symptoms were assessed using the Inventory of Depressive Symptomatology (IDS-SR30) at baseline and 1.5 and 3 months after randomization. Results: Residual depressive symptoms showed a small but statistically significant decrease in the intention-to-treat group over 3 months in the mobile CT group relative to the TAU group (difference: -1.60 points on the IDS-SR30 per month, 95% CI = -2.64 to -0.56, p = 0.003). The effect of the treatment condition on the depressive symptomatology at the 3-month follow-up was small to moderate (Cohen's d = 0.44). All analyses among completers (≥5 modules) showed more pronounced treatment effects. Adjustment for unequally distributed variables did not markedly affect the results. Conclusions: Residual depressive symptoms after remission showed a more favorable course over 3 months in the mobile CT group compared to the TAU group. These results are a first indication that mobile CT in addition to TAU is effective in treating recurrently depressed patients in remission. However, demonstration of its long-term effectiveness and replication remains necessary.",
keywords = "Cognitive therapy, Internet-based therapy, Monitoring, Recurrent depression, Treatment, Health sciences",
author = "Gemma Kok and Huibert Burger and Heleen Riper and Pim Cuijpers and Jack Dekker and {Van Marwijk}, Harm and Filip Smit and Aaron Beck and Bockting, {Claudi L H}",
year = "2015",
doi = "10.1159/000369469",
language = "English",
volume = "84",
pages = "90--99",
journal = "Psychotherapy and Psychosomatics",
issn = "0033-3190",
publisher = "S. Karger AG",
number = "2",

}

RIS

TY - JOUR

T1 - The three-month effect of mobile internet-based cognitive therapy on the course of depressive symptoms in remitted recurrently depressed patients

T2 - Results of a randomized controlled trial

AU - Kok, Gemma

AU - Burger, Huibert

AU - Riper, Heleen

AU - Cuijpers, Pim

AU - Dekker, Jack

AU - Van Marwijk, Harm

AU - Smit, Filip

AU - Beck, Aaron

AU - Bockting, Claudi L H

PY - 2015

Y1 - 2015

N2 - Background: Internet-based cognitive therapy with monitoring via text messages (mobile CT), in addition to treatment as usual (TAU), might offer a cost-effective way to treat recurrent depression. Method: Remitted patients with at least 2 previous episodes of depression were randomized to mobile CT in addition to TAU (n = 126) or TAU only (n = 113). A linear mixed model was used to examine the effect of the treatment condition on a 3-month course of depressive symptoms after remission. Both an intention-to-treat analysis (n = 239) and a completer analysis (n = 193) were used. Depressive symptoms were assessed using the Inventory of Depressive Symptomatology (IDS-SR30) at baseline and 1.5 and 3 months after randomization. Results: Residual depressive symptoms showed a small but statistically significant decrease in the intention-to-treat group over 3 months in the mobile CT group relative to the TAU group (difference: -1.60 points on the IDS-SR30 per month, 95% CI = -2.64 to -0.56, p = 0.003). The effect of the treatment condition on the depressive symptomatology at the 3-month follow-up was small to moderate (Cohen's d = 0.44). All analyses among completers (≥5 modules) showed more pronounced treatment effects. Adjustment for unequally distributed variables did not markedly affect the results. Conclusions: Residual depressive symptoms after remission showed a more favorable course over 3 months in the mobile CT group compared to the TAU group. These results are a first indication that mobile CT in addition to TAU is effective in treating recurrently depressed patients in remission. However, demonstration of its long-term effectiveness and replication remains necessary.

AB - Background: Internet-based cognitive therapy with monitoring via text messages (mobile CT), in addition to treatment as usual (TAU), might offer a cost-effective way to treat recurrent depression. Method: Remitted patients with at least 2 previous episodes of depression were randomized to mobile CT in addition to TAU (n = 126) or TAU only (n = 113). A linear mixed model was used to examine the effect of the treatment condition on a 3-month course of depressive symptoms after remission. Both an intention-to-treat analysis (n = 239) and a completer analysis (n = 193) were used. Depressive symptoms were assessed using the Inventory of Depressive Symptomatology (IDS-SR30) at baseline and 1.5 and 3 months after randomization. Results: Residual depressive symptoms showed a small but statistically significant decrease in the intention-to-treat group over 3 months in the mobile CT group relative to the TAU group (difference: -1.60 points on the IDS-SR30 per month, 95% CI = -2.64 to -0.56, p = 0.003). The effect of the treatment condition on the depressive symptomatology at the 3-month follow-up was small to moderate (Cohen's d = 0.44). All analyses among completers (≥5 modules) showed more pronounced treatment effects. Adjustment for unequally distributed variables did not markedly affect the results. Conclusions: Residual depressive symptoms after remission showed a more favorable course over 3 months in the mobile CT group compared to the TAU group. These results are a first indication that mobile CT in addition to TAU is effective in treating recurrently depressed patients in remission. However, demonstration of its long-term effectiveness and replication remains necessary.

KW - Cognitive therapy

KW - Internet-based therapy

KW - Monitoring

KW - Recurrent depression

KW - Treatment

KW - Health sciences

UR - http://www.scopus.com/inward/record.url?scp=84924202096&partnerID=8YFLogxK

U2 - 10.1159/000369469

DO - 10.1159/000369469

M3 - Journal articles

C2 - 25721915

AN - SCOPUS:84924202096

VL - 84

SP - 90

EP - 99

JO - Psychotherapy and Psychosomatics

JF - Psychotherapy and Psychosomatics

SN - 0033-3190

IS - 2

ER -

DOI

Recently viewed

Publications

  1. Förderung von Diagnose- und Interventionskompetenzen mithilfe von Praxisbezügen – Konzeption eines Seminars für die erste Phase der Lehrkräfteausbildung
  2. Lesestrategien zur Unterstützung des Verstehens von Textaufgaben. Vermittlung und Routinen im Mathematikunterricht aus Sicht von Lehrkräften und Lernenden
  3. Competence models for assessing individual learning outcomes and evaluating educational processes - a priority program of the German research foundation (DFG)
  4. Use of Machine-Learning Algorithms Based on Text, Audio and Video Data in the Prediction of Anxiety and Post-Traumatic Stress in General and Clinical Populations
  5. Korngrößenabhängigkeit der Verteilung ausgesuchter schwerflüchtiger organischer Substanzen in Flusssedimenten und Schlussfolgerungen für die Sedimentanalytik
  6. Effects of Soil Properties, Temperature and Disturbance on Diversity and Functional Composition of Plant Communities Along a Steep Elevational Gradient on Tenerife
  7. Reduced nitrate leaching from an Irish cropland soil under non-inversion tillage with cover cropping greatly outweighs increased dissolved organic nitrogen leaching
  8. Berechnung von Eisengehalten und Verockerungspotential von Schluckbrunnen mithilfe von Temperatur-, Redoxpotential-, pH-Wert-, Leitfähigkeits- und Sauerstoffsättigungsdaten
  9. Stenotypy and eurytopy - Distribution models as a tool for estimating niche overlap in two spider species, Trochosa terricola and Eresus kollari (Araneae: Lycosidae/Eresidae).
  10. Die Jahrgangsmischung auf dem Prüfstand: Effekte jahrgangsübergreifenden Lernens auf Kompetenzen und sozio-emotionales Wohlbefinden von Grundschülerinnen und Grundschülern
  11. Determination of the construction and the material identity values of outside building components with the help of in-situ measuring procedures and FEM-simulation calculations
  12. The Role of Linked Social-Ecological Systems in a Mobile Agent-Based Ecosystem Service from Giant Honey Bees (Apis dorsata) in an Indigenous Community Forest in Palawan, Philippines
  13. Neanderthals in changing environments from MIS 5 to early MIS 4 in northern Central Europe – Integrating archaeological, (chrono)stratigraphic and paleoenvironmental evidence at the site of Lichtenberg