Techniques to Control Microbial Contaminants in Nonsterile Microalgae Cultivation

Research output: Journal contributionsScientific review articlesResearch


The aim of this mini-review with own results was an identification of techniques to suppress the growth of microbial contaminants under photo- and mixotrophic conditions. Techniques identified are the modification of environmental conditions, such as pH, oxygen, and nutrient concentrations, as well as the application of pulsed electric field, ultrasonication, and surfactants. In phototrophic cultivations, the mentioned techniques result in a decrease of number of predatory cells, but not in a complete removal. Measures to suppress the growth of contaminations (e.g., bacteria and fungi) in mixotrophic cultivations could not be identified. The co-cultivation of algae and fungi, however, was found to be beneficial for the utilization of unusual carbon compounds (e.g., phenolic compounds).
Original languageEnglish
JournalApplied Biochemistry and Biotechnology
Issue number4
Pages (from-to)1376-1385
Number of pages10
Publication statusPublished - 01.12.2020

Bibliographical note

Funding Information:
DP and AL acknowledge the financial support from the ERA-Net Cofound Action—under H2020—and the German Federal Ministry of Education and Research for carrying out the research project “Era CoBioTech 1: Biovalorization of olive mill wastewater (OMW) to microbial lipids and other products via Rhodotorula glutinis fermentation (Rhodolive, 031B0607A).” ARR acknowledges the facilities supported by DST-FIST (Project No: LSI-576/2013), Govt. of India, and VFSTR University.

Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.

    Research areas

  • Biology - Contamination, Xenic conditions, Bioeconomy, Heterotrophy, Phototrophic