Human and veterinary drugs in the environment
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Encyclopedia of the Anthropocene. Vol. 1-5 Elsevier B.V., 2017. p. 263-268.
Research output: Contributions to collected editions/works › Articles for encyclopedia › Research
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TY - CHAP
T1 - Human and veterinary drugs in the environment
AU - Rastogi, Tushar
AU - Ahmed, Waleed Mohamed Mamdouh Mahmoud
AU - Kümmerer, Klaus
N1 - Publisher Copyright: © 2018 Elsevier Inc. All rights reserved.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Pharmaceutical micropollutants in the environment are seen as a threat to health, water, and food safety. Drug residues present in the environment impose adverse effects to aquatic world. Recent research has shown that this problem cannot be solved with advanced treatment processes. Very often, pharmaceuticals are transformed to other products. Effects and risk assessments are generally performed based on single compounds instead of cocktail mixture which is not the situation in the environment. The sustainable solution for pharmaceutical emerging contaminants in the environment will be benign by design, which can be the paradigm of the future. Benign by design means that easy (bio)degradability of pharmaceuticals (and/or chemicals) after use or application is taken into account even before it is synthesized, that is, during the lead optimization stages. It is an important concept within green and sustainable pharmacy and chemistry and very promising in terms of sustainability.
AB - Pharmaceutical micropollutants in the environment are seen as a threat to health, water, and food safety. Drug residues present in the environment impose adverse effects to aquatic world. Recent research has shown that this problem cannot be solved with advanced treatment processes. Very often, pharmaceuticals are transformed to other products. Effects and risk assessments are generally performed based on single compounds instead of cocktail mixture which is not the situation in the environment. The sustainable solution for pharmaceutical emerging contaminants in the environment will be benign by design, which can be the paradigm of the future. Benign by design means that easy (bio)degradability of pharmaceuticals (and/or chemicals) after use or application is taken into account even before it is synthesized, that is, during the lead optimization stages. It is an important concept within green and sustainable pharmacy and chemistry and very promising in terms of sustainability.
KW - Benign by design
KW - Emerging contaminants
KW - Environment fate
KW - Legalization
KW - Metabolite
KW - Pharmaceutical micropollutant
KW - Risk assessment
KW - Sustainable chemistry
KW - Toxicity
KW - Transformation product
KW - Wastewater treatment
KW - Chemistry
UR - http://www.scopus.com/inward/record.url?scp=85051957310&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-809665-9.09991-2
DO - 10.1016/B978-0-12-809665-9.09991-2
M3 - Articles for encyclopedia
AN - SCOPUS:85051957310
SN - 9780128135761
VL - 1-5
SP - 263
EP - 268
BT - Encyclopedia of the Anthropocene
PB - Elsevier B.V.
ER -