TY - JOUR

T1 - Ciprofloxacin in Hospital Effluent

T2 - Degradation by Ozone and Photoprocesses

AU - Vasconcelos, Tibiriça G.

AU - Kümmerer, Klaus

AU - Henriques, Danielle M

AU - Martins, Ayrton F

PY - 2009/9/30

Y1 - 2009/9/30

N2 - There are several papers in the literature that have recorded satisfactory results for the degradation of different pharmaceuticals in aqueous solutions by means of oxidation processes; however, only a few of them relied on real samples in carrying out their investigations. This study examines the results of the performance of photo-induced oxidation, heterogeneous photocatalysis, ozonation and peroxone in degrading the fluoroquinolone antimicrobial ciprofloxacin (CIP) in a hospital effluent. The real samples were collected from the treatment system of the University Hospital of Santa Maria (HUSM). Liquid chromatography with fluorescence detection (LC-FLD) was used to monitor the decrease of the CIP concentration. As expected, photo-induced oxidation was much slower than the other processes in bringing about total CIP degradation. Both heterogeneous photocatalysis and peroxone led to almost complete CIP degradation after 60 min treatment. Ozonation showed the best performance: total degradation after 30 min treatment. This was an unexpected result in view of the greater capacity of the other two processes to generate hydroxyl radicals. However, this finding supports a result in the literature that has tended to be overlooked. The by-products formed during the application of the processes were found to be very similar. Moreover, on the basis of the data obtained from the literature, there is some evidence to suggest that the by-products are derived from the oxidation of the piperazine group. © 2009 Elsevier B.V.

AB - There are several papers in the literature that have recorded satisfactory results for the degradation of different pharmaceuticals in aqueous solutions by means of oxidation processes; however, only a few of them relied on real samples in carrying out their investigations. This study examines the results of the performance of photo-induced oxidation, heterogeneous photocatalysis, ozonation and peroxone in degrading the fluoroquinolone antimicrobial ciprofloxacin (CIP) in a hospital effluent. The real samples were collected from the treatment system of the University Hospital of Santa Maria (HUSM). Liquid chromatography with fluorescence detection (LC-FLD) was used to monitor the decrease of the CIP concentration. As expected, photo-induced oxidation was much slower than the other processes in bringing about total CIP degradation. Both heterogeneous photocatalysis and peroxone led to almost complete CIP degradation after 60 min treatment. Ozonation showed the best performance: total degradation after 30 min treatment. This was an unexpected result in view of the greater capacity of the other two processes to generate hydroxyl radicals. However, this finding supports a result in the literature that has tended to be overlooked. The by-products formed during the application of the processes were found to be very similar. Moreover, on the basis of the data obtained from the literature, there is some evidence to suggest that the by-products are derived from the oxidation of the piperazine group. © 2009 Elsevier B.V.

KW - Chemistry

KW - Ciprofloxacin

KW - degradation

KW - ozone

KW - Photodegradation

KW - Anti-Infective Agents

KW - Ciprofloxacin

KW - Environmental Remediation

KW - Fluoroquinolones

KW - Hospitals

KW - Ozone

KW - Photochemical Processes

UR - http://www.scopus.com/inward/record.url?scp=67649794832&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/3b0739b7-2773-30fc-94c1-a9307cdd6fc9/

U2 - 10.1016/j.jhazmat.2009.03.143

DO - 10.1016/j.jhazmat.2009.03.143

M3 - Journal articles

C2 - 19428183

VL - 169

SP - 1154

EP - 1158

JO - Journal of Hazardous Materials

JF - Journal of Hazardous Materials

SN - 1873-3336

IS - 1-3

ER -