Internet-based treatment of major depression for patients on a waiting list for inpatient psychotherapy: protocol for a multi-centre randomised controlled trial

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

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Internet-based treatment of major depression for patients on a waiting list for inpatient psychotherapy: protocol for a multi-centre randomised controlled trial. / Reins, Jo Annika; Ebert, David Daniel; Lehr, Dirk et al.
in: BMC Psychiatry, Jahrgang 13, Nr. November, 318, 26.11.2013.

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

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@article{552be6fc993b4d50b5e93f88cc616d80,
title = "Internet-based treatment of major depression for patients on a waiting list for inpatient psychotherapy: protocol for a multi-centre randomised controlled trial",
abstract = "Background: Major depressive disorder (MDD) is a prevalent and severe disorder. Although effective treatments for MDD are available, many patients remain untreated, mainly because of insufficient treatment capacities in the health care system. Resulting waiting periods are often associated with prolonged suffering and impairment as well as a higher risk of chronification. Web-based interventions may help to alleviate these problems. Numerous studies provided evidence for the efficacy of web-based interventions for depression. The aim of this study is to evaluate a new web-based guided self-help intervention (GET.ON-Mood Enhancer-WL) specifically developed for patients waiting to commence inpatient therapy for MDD.Methods: In a two-armed randomised controlled trial (n = 200), the web-based guided intervention GET.ON-Mood Enhancer-WL in addition to treatment as usual (TAU) will be compared with TAU alone. The intervention contains six modules (psycho education, behavioural activation I & II, problem solving I & II, and preparation for subsequent inpatient depression therapy). The participants will be supported by an e-coach, who will provide written feedback after each module. Inclusion criteria include a diagnosis of MDD assessed with a structured clinical interview [SCID] and a waiting period of at least three weeks before start of inpatient treatment. The primary outcome is observer-rated depressive symptom severity (HRSD 24). Further (explorative) questions include whether remission will be achieved earlier and by more patients during inpatient therapy because of the web-based preparatory intervention.Discussion: If GET.ON-Mood Enhancer-WL is proven to be effective, patients may start inpatient therapy with reduced depressive symptom severity, ideally leading to higher remission rates, shortened inpatient therapy, reduced costs, and decreased waiting times.Trial registration: German Clinical Trial Registration (DRKS): DRKS00004708.",
keywords = "Psychology, Health sciences, Inpatient treatment, Internet therapy, Major depression, Remission, Waiting time",
author = "Reins, {Jo Annika} and Ebert, {David Daniel} and Dirk Lehr and Heleen Riper and Pim Cuijpers and Matthias Berking",
note = "Funding Information: This study is funded by the European Union (EFRE: ZW6-80119999, CCI 2007DE161PR001).",
year = "2013",
month = nov,
day = "26",
doi = "10.1186/1471-244X-13-318",
language = "English",
volume = "13",
journal = "BMC Psychiatry",
issn = "1471-244X",
publisher = "BioMed Central Ltd.",
number = "November",

}

RIS

TY - JOUR

T1 - Internet-based treatment of major depression for patients on a waiting list for inpatient psychotherapy

T2 - protocol for a multi-centre randomised controlled trial

AU - Reins, Jo Annika

AU - Ebert, David Daniel

AU - Lehr, Dirk

AU - Riper, Heleen

AU - Cuijpers, Pim

AU - Berking, Matthias

N1 - Funding Information: This study is funded by the European Union (EFRE: ZW6-80119999, CCI 2007DE161PR001).

PY - 2013/11/26

Y1 - 2013/11/26

N2 - Background: Major depressive disorder (MDD) is a prevalent and severe disorder. Although effective treatments for MDD are available, many patients remain untreated, mainly because of insufficient treatment capacities in the health care system. Resulting waiting periods are often associated with prolonged suffering and impairment as well as a higher risk of chronification. Web-based interventions may help to alleviate these problems. Numerous studies provided evidence for the efficacy of web-based interventions for depression. The aim of this study is to evaluate a new web-based guided self-help intervention (GET.ON-Mood Enhancer-WL) specifically developed for patients waiting to commence inpatient therapy for MDD.Methods: In a two-armed randomised controlled trial (n = 200), the web-based guided intervention GET.ON-Mood Enhancer-WL in addition to treatment as usual (TAU) will be compared with TAU alone. The intervention contains six modules (psycho education, behavioural activation I & II, problem solving I & II, and preparation for subsequent inpatient depression therapy). The participants will be supported by an e-coach, who will provide written feedback after each module. Inclusion criteria include a diagnosis of MDD assessed with a structured clinical interview [SCID] and a waiting period of at least three weeks before start of inpatient treatment. The primary outcome is observer-rated depressive symptom severity (HRSD 24). Further (explorative) questions include whether remission will be achieved earlier and by more patients during inpatient therapy because of the web-based preparatory intervention.Discussion: If GET.ON-Mood Enhancer-WL is proven to be effective, patients may start inpatient therapy with reduced depressive symptom severity, ideally leading to higher remission rates, shortened inpatient therapy, reduced costs, and decreased waiting times.Trial registration: German Clinical Trial Registration (DRKS): DRKS00004708.

AB - Background: Major depressive disorder (MDD) is a prevalent and severe disorder. Although effective treatments for MDD are available, many patients remain untreated, mainly because of insufficient treatment capacities in the health care system. Resulting waiting periods are often associated with prolonged suffering and impairment as well as a higher risk of chronification. Web-based interventions may help to alleviate these problems. Numerous studies provided evidence for the efficacy of web-based interventions for depression. The aim of this study is to evaluate a new web-based guided self-help intervention (GET.ON-Mood Enhancer-WL) specifically developed for patients waiting to commence inpatient therapy for MDD.Methods: In a two-armed randomised controlled trial (n = 200), the web-based guided intervention GET.ON-Mood Enhancer-WL in addition to treatment as usual (TAU) will be compared with TAU alone. The intervention contains six modules (psycho education, behavioural activation I & II, problem solving I & II, and preparation for subsequent inpatient depression therapy). The participants will be supported by an e-coach, who will provide written feedback after each module. Inclusion criteria include a diagnosis of MDD assessed with a structured clinical interview [SCID] and a waiting period of at least three weeks before start of inpatient treatment. The primary outcome is observer-rated depressive symptom severity (HRSD 24). Further (explorative) questions include whether remission will be achieved earlier and by more patients during inpatient therapy because of the web-based preparatory intervention.Discussion: If GET.ON-Mood Enhancer-WL is proven to be effective, patients may start inpatient therapy with reduced depressive symptom severity, ideally leading to higher remission rates, shortened inpatient therapy, reduced costs, and decreased waiting times.Trial registration: German Clinical Trial Registration (DRKS): DRKS00004708.

KW - Psychology

KW - Health sciences

KW - Inpatient treatment

KW - Internet therapy

KW - Major depression

KW - Remission

KW - Waiting time

UR - http://www.scopus.com/inward/record.url?scp=84888187934&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/3646046f-eb4d-3b4f-81aa-85bacf953691/

U2 - 10.1186/1471-244X-13-318

DO - 10.1186/1471-244X-13-318

M3 - Journal articles

C2 - 24279841

VL - 13

JO - BMC Psychiatry

JF - BMC Psychiatry

SN - 1471-244X

IS - November

M1 - 318

ER -

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