The ten principles of GSP are presented with the aim of establishing a road map toward the development of overall greener analytical methodologies. Paramount aspects for greening sample preparation and their interconnections are identified and discussed. These include the use of safe solvents/reagents and materials that are renewable, recycled and reusable, minimizing waste generation and energy demand, and enabling high sample throughput, miniaturization, procedure simplification/automation, and operator's safety. Further, the importance of applying green metrics for assessing the greenness of sample preparation methods is highlighted, next to the contribution of GSP in achieving the broader goal of sustainability. Green sample preparation is sample preparation. It is not a new subdiscipline of sample preparation but a guiding principle that promotes sustainable development through the adoption of environmentally benign sample preparation procedures.