Photodegradation, Photocatalytic and Aerobic Biodegradation of Sulfisomidine and Identification of Transformation Products By LC–UV-MS/MS
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In: Clean - Soil, Air, Water, Vol. 40, No. 11, 11.2012, p. 1244-1249.
Research output: Journal contributions › Journal articles › Research › peer-review
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TY - JOUR
T1 - Photodegradation, Photocatalytic and Aerobic Biodegradation of Sulfisomidine and Identification of Transformation Products By LC–UV-MS/MS
AU - Sleman, Faten
AU - Mahmoud, Waleed M. M.
AU - Schubert, Rolf
AU - Kümmerer, Klaus
PY - 2012/11
Y1 - 2012/11
N2 - Much attention has recently been devoted to the fate and effects of pharmaceuticals in the water cycle. Removal of antibiotics in effluents by photo-treatment or biodegradation is a topic currently under discussion. Degradation and removal efficiencies of sulfisomidine (SUI) by photodegradation and aerobic biodegradability were studied. SUI behavior was monitored during photolysis and photocatalysis (catalyst titanium dioxide) using 150-W medium-pressure Hg lamp. Also an aerobic bacterial degradation test from the OECD series (closed bottle test (CBT, OECD 301 D)) was performed. The primary elimination of SUI was monitored. Structures of photo-degradation products were assessed by chromatographic separation on a C18 column with ultraviolet detection at 270nm and ion trap MS. The results demonstrate that SUI is not readily biodegradable in CBT. Photo catalysis was more is effective than photolysis. SUI underwent photodegradation and several SUI photoproducts were identified. Accordingly, the photodegradation pathway of SUI was postulated. When reaching the aquatic environment, SUI and its photo products can constitute a risk to the environment.
AB - Much attention has recently been devoted to the fate and effects of pharmaceuticals in the water cycle. Removal of antibiotics in effluents by photo-treatment or biodegradation is a topic currently under discussion. Degradation and removal efficiencies of sulfisomidine (SUI) by photodegradation and aerobic biodegradability were studied. SUI behavior was monitored during photolysis and photocatalysis (catalyst titanium dioxide) using 150-W medium-pressure Hg lamp. Also an aerobic bacterial degradation test from the OECD series (closed bottle test (CBT, OECD 301 D)) was performed. The primary elimination of SUI was monitored. Structures of photo-degradation products were assessed by chromatographic separation on a C18 column with ultraviolet detection at 270nm and ion trap MS. The results demonstrate that SUI is not readily biodegradable in CBT. Photo catalysis was more is effective than photolysis. SUI underwent photodegradation and several SUI photoproducts were identified. Accordingly, the photodegradation pathway of SUI was postulated. When reaching the aquatic environment, SUI and its photo products can constitute a risk to the environment.
KW - Chemistry
KW - Antibiotic
KW - Biodegradation
KW - Closed bottle test
KW - pharmaceutical
KW - Photo-treatment
KW - Titanium dioxide
KW - Sustainability Science
UR - http://www.scopus.com/inward/record.url?scp=84869238214&partnerID=8YFLogxK
U2 - 10.1002/clen.201100485
DO - 10.1002/clen.201100485
M3 - Journal articles
VL - 40
SP - 1244
EP - 1249
JO - Clean - Soil, Air, Water
JF - Clean - Soil, Air, Water
SN - 1863-0669
IS - 11
ER -