Homogenization for a non-local coupling model

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In [P. Deuflhard and R. Hochmuth, On the thermoregulation in the human microvascular system, Proc. Appl. Math. Mech. 3 (2003), pp. 378–379; P. Deuflhard and R. Hochmuth, Multiscale analysis of thermoregulation in the human microsvascular system, Math. Meth. Appl. Sci. 27 (2004), pp. 971–989; R. Hochmuth and P. Deuflhard, Multiscale analysis for the bio-heat transfer equation–the nonisolated case, Math. Models Methods Appl. Sci. 14(11) (2004), pp. 1621–1634], homogenization techniques are applied to derive an anisotropic variant of the bio-heat transfer equation as asymptotic result of boundary value problems providing a microscopic description for microvascular tissue. In view of a future application on treatment planning in hyperthermia, we investigate here the homogenization limit for a coupling model, which takes additionally into account the influence of convective heat transfer in medium-size blood vessels. This leads to second-order elliptic boundary value problems with non-local boundary conditions on parts of the boundary. Moreover, we present asymptotic estimates for first-order correctors.

Original languageEnglish
JournalApplicable analysis. An international journal
Issue number12
Pages (from-to)1311-1323
Number of pages13
Publication statusPublished - 12.2008
Externally publishedYes

    Research areas

  • Mathematics - homogenization, non-local boundary conditions, Robin boundary, conditions, correctors, heat transfer, bio-heat equation, hyperthermia