Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Journal articles › Research › Peer-reviewed
- Published
Optimization and validation of an HPLC-UV method for determination of tranexamic acid in a dosage form and in human urine.
Hadad, G. M., El-Gindy, A. & Mahmoud, W. M. M., 09.2007, In: Chromatographia. 66, 5-6, p. 311-317 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 12.2009, In: Chromatographia. 70, 11/12, p. 1593–1598 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Oxidation-coagulation of β-blockers by K2Fe(VI)O4 in hospital wastewater: Assessment of degradation products and biodegradability
Wilde, M. L., Mahmoud, W. M. M., Kümmerer, K. & Martins, A. F., 01.05.2013, In: The Science of The Total Environment. 452-453, p. 137-147 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
PharmCycle: a holistic approach to reduce the contamination of the aquatic environment with antibiotics by developing sustainable antibiotics, improving the environmental risk assessment of antibiotics, and reducing the discharges of antibiotics in the wastewater outlet
Andrae, J., Beyer, F., Cornelissen, G., Einfeldt, J., Heseding, J., Kuemmerer, K., Oelkers, K. & Floeter, C., 01.12.2018, In: Environmental Sciences Europe. 30, 1, 15 p., 24.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of micropollutants using V-UV/UV-C processes: Triclosan as a model compound
Alfiya, Y., Friedler, E., Westphal, J., Olsson, O. & Dubowski, Y., 01.12.2017, In: The Science of The Total Environment. 601-602, p. 397-404 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of the antineoplastic cyclophosphamide: A comparative study of the efficiencies of UV/H2O2, UV/Fe(2+)/H2O2 and UV/TiO2 processes
Lutterbeck, C. A., Machado, E. L. & Kümmerer, K., 01.02.2015, In: Chemosphere. 120, p. 538-546 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation of the UV filter ethylhexyl methoxycinnamate under ultraviolet light: identification and in silico assessment of photo-transformation products in the context of grey water reuse
Jentzsch, F., Olsson, O., Westphal, J., Reich, M., Leder, C. & Kümmerer, K., 01.12.2016, In: The Science of The Total Environment. 572, p. 1092-1100 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photodegradation, Photocatalytic and Aerobic Biodegradation of Sulfisomidine and Identification of Transformation Products By LC–UV-MS/MS
Sleman, F., Mahmoud, W. M. M., Schubert, R. & Kümmerer, K., 11.2012, In: Clean - Soil, Air, Water. 40, 11, p. 1244-1249 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photolysis of mixtures of UV filters octocrylene and ethylhexyl methoxycinnamate leads to formation of mixed transformation products and different kinetics
Jentzsch, F., Reich, M., Kümmerer, K. & Olsson, O., 20.12.2019, In: Science of the Total Environment. 697, 9 p., 134048.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photolysis of sulfamethoxypyridazine in various aqueous media: Aerobic biodegradation and identification of photoproducts by LC-UV-MS/MS
Khaleel, N. D. H., Mahmoud, W. M. M., Hadad, G. M., Abdel-Salam, R. A. & Kümmerer, K., 15.01.2013, In: Journal of Hazardous Materials. 244-245, p. 654-661 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photolytic transformation products and biological stability of the hydrological tracer Uranine
Gutowski, L., Olsson, O., Lange, J. & Kümmerer, K., 15.11.2015, In: The Science of The Total Environment. 533, p. 446-453 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Physico-chemical characteristics affect the spatial distribution of pesticide and transformation product loss to an agricultural brook
Gassmann, M., Olsson, O., Stamm, C., Weiler, M. & Kümmerer, K., 01.11.2015, In: The Science of The Total Environment. 532, p. 733-743 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Physicochemical properties and biodegradability of organically functionalized colloidal silica particles in aqueous environment
Schneider, M., Meder, F., Haiß, A., Treccani, L., Rezwan, K. & Kümmerer, K., 03.2014, In: Chemosphere. 99, p. 96-101 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Possible underestimations of risks for the environment due to unregulated emissions of biocides from households to wastewater
Wieck, S., Olsson, O. & Kümmerer, K., 01.09.2016, In: Environmental international. 94, p. 695-705 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Priming of CD8+ T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice.
Pavlenko, M., Leder, C., Moreno, S., Levitsky, V. & Pisa, P., 21.08.2007, In: Vaccine. 25, 34, p. 6341-6347 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Putting benign by design into practice-novel concepts for green and sustainable pharmacy: Designing green drug derivatives by non-targeted synthesis and screening for biodegradability
Leder, C., Rastogi, T. & Kümmerer, K., 01.12.2015, In: Sustainable Chemistry and Pharmacy. 2, p. 31-36 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Putting sustainable chemistry and resource use into context: The role of temporal diversity
Weiser, A., Lang, D. J. & Kümmerer, K., 01.06.2017, In: Sustainable Chemistry and Pharmacy. 5, p. 105-114 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Qualitative environmental risk assessment of photolytic transformation products of iodinated X-ray contrast agent diatrizoic acid
Rastogi, T., Leder, C. & Kümmerer, K., 01.06.2014, In: The Science of The Total Environment. 482-483, 1, p. 378-388 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Quantum Chemical Calculation and Evaluation of Partition Coefficients for Classical and Emerging Environmentally Relevant Organic Compounds
Salthammer, T., Grimme, S., Stahn, M., Hohm, U. & Palm, W. U., 04.01.2022, In: Environmental Science and Technology. 56, 1, p. 379-391 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Quantum chemical calculation of the vapor pressure of volatile and semi volatile organic compounds
Stahn, M., Grimme, S., Salthammer, T., Hohm, U. & Palm, W-U., 03.10.2022, In: Environmental Sciences: Processes & Impacts. 24, 11, p. 2153-2166 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Ready biodegradability of trifluoromethylated phenothiazine drugs, structural elucidation of their aquatic transformation products, and identification of environmental risks studied by LC-MS( n ) and QSAR
Trautwein, C. & Kümmerer, K., 09.2012, In: Environmental Science and Pollution Research. 19, 8, p. 3162-3177 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Recalcitrant pharmaceuticals in the aquatic environment: A comparative screening study of their occurrence, formation of phototransformation products and their in vitro toxicity
Bergheim, M., Gminski, R., Spangenberg, B., Dȩbiak, M., Bürkle, A., Mersch-Sundermann, V., Kümmerer, K. & Gieré, R., 2014, In: Environmental Chemistry. 11, 4, p. 431-444 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Reducing aquatic micropollutants – Increasing the focus on input prevention and integrated emission management
Kümmerer, K., Dionysiou, D. D., Olsson, O. & Fatta-Kassinos, D., 20.02.2019, In: Science of the Total Environment. 652, p. 836-850 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Reducing Environmental Pollution by Antibiotics through Design for Environmental Degradation
Leder, C., Suk, M., Lorenz, S., Rastogi, T., Pfeifer, C., Kietzmann, M., Jonas, D., Buck, M., Pahl, A. & Kümmerer, K., 19.07.2021, In: ACS Sustainable Chemistry & Engineering. 9, 28, p. 9358–9368 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Release of monomers from four different composite materials after halogen and LED curing
Polydorou, O., König, A., Altenburger, M. J., Wolkewitz, M., Hellwig, E. & Kümmerer, K., 01.10.2011, In: American Journal of Dentistry. 24, 5, p. 315-321 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Reliving the past in a changed environment: Hydropower ambitions, opportunities and constraints in Tajikistan
Wegerich, K., Olsson, O. & Froebrich, J., 01.07.2007, In: Energy Policy. 35, 7, p. 3815-3825 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Removal of dexamethasone from aqueous solution and hospital wastewater by electrocoagulation
Arsand, D. R., Kümmerer, K. & Martins, A. F., 15.01.2013, In: The Science of The Total Environment. 443, p. 351-357 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Removal of the anti-cancer drug methotrexate from water by advanced oxidation processes: Aerobic biodegradation and toxicity studies after treatment
Lutterbeck, C. A., Baginska, E., Machado, Ê. L. & Kümmerer, K., 12.2015, In: Chemosphere. 141, p. 290-296 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Response to David B. Brooks
Wegerich, K. & Olsson, O., 05.2011, In: Water International. 36, 3, p. 410-413 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
River flow regime and snow cover of the Pamir Alay (Central Asia) in a changing climate
Chevallier, P., Pouyaud, B., Mojaisky, M., Bolgov, M., Olsson, O., Bauer, M. & Froebrich, J., 08.2014, In: Hydrological Sciences Journal. 59, 8, p. 1491-1506 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Semi-micro reflux procedure for minimization of chloride interference by COD determination.
Martins, A. F., de Jesus, L. E. W., Vendruscolo, N., Vasconcelos, T. G. & Wilde, M. L., 25.01.2008, In: Clean - Soil, Air, Water. 36, 1, p. 66-69 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Sensory Perception of Non-Deuterated and Deuterated Organic Compounds
Salthammer, T., Monegel, F., Schulz, N., Uhde, E., Grimme, S., Seibert, J., Hohm, U. & Palm, W. U., 13.01.2021, In: Chemistry - A European Journal. 27, 3, p. 1046-1056 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Simultaneous Determination of 11 Sulfonamides by HPLC–UV and Application for Fast Screening of Their Aerobic Elimination and Biodegradation in a Simple Test
Mahmoud, W. M. M., Khaleel, N. D. H., Hadad, G. M., Abdel-Salam, R. A., Haiß, A. & Kümmerer, K., 09.2013, In: Clean - Soil, Air, Water. 41, 9, p. 907-916 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Sources and pathways of biocides and their transformation products in urban storm water infrastructure of a 2 ha urban district
Linke, F., Olsson, O., Preusser, F., Kümmerer, K., Schnarr, L., Bork, M. & Lange, J., 20.08.2021, In: Hydrology and Earth System Sciences. 25, 8, p. 4495-4512 18 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa
Nantaba, F., Wasswa, J., Kylin, H., Bouwman, H., Palm, W-U. & Kümmerer, K., 01.01.2024, In: Science of the Total Environment. 906Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Species Identification of Bacteria and Fungi from Solid and Liquid Culture Media by MALDI-TOF Mass Spectrometry
Reich, M., Bosshard, P. P., Stark, M., Beyser, K. & Borgmann, S., 22.01.2013, In: Journal of Bacteriology & Parasitology. 4, S5, 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies
Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T. G., Gueutin, C., Guterres, S. S., Pohlmann, A. R. & Fattal, E., 21.08.2011, In: Soft Matter. 7, 16, p. 7304-7312 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Studying the fate of the drug Chlorprothixene and its photo transformation products in the aquatic environment: Identification, assessment and priority setting by application of a combination of experiments and various in silico assessments
Khaleel, N. D. H., Mahmoud, W. M. M., Olsson, O. & Kümmerer, K., 01.02.2019, In: Water Research. 149, p. 467-476 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Sustainable chemistry and the international sustainable chemistry collaborative centre ISC 3
Elschami, M., Kümmerer, K. & Schneidewind, U., 01.01.2018, In: GAIA. 27, 2, p. 247-249 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Synthesis of Room-Temperature Ionic Liquids with the Weakly Coordinating [Al(ORF)(4)](-) Anion (R-F = C(H)(CF3)(2)) and the Determination of Their Principal Physical Properties
Bulut, S., Klose, P., Huang, M-M., Weingartner, H., Dyson, P. J., Laurenczy, G., Friedrich, C., Menz, J., Kummerer, K. & Krossing, I., 22.11.2010, In: Chemistry - A European Journal. 16, 44, p. 13139-13154 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Synthesis, self-assembly, bacterial and fungal toxicity, and preliminary biodegradation studies of a series of L-phenylalanine-derived surface-active ionic liquids
Kapitanov, I. V., Jordan, A., Karpichev, Y., Spulak, M., Perez, L., Kellett, A., Kümmerer, K. & Gathergood, N., 07.04.2019, In: Green Chemistry . 21, 7, p. 1777-1794 18 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Targeted metabolomics of pellicle and saliva in children with different caries activity
Schulz, A., Lang, R., Behr, J., Hertel, S., Reich, M., Kümmerer, K., Hannig, M., Hannig, C. & Hofmann, T., 01.12.2020, In: Scientific Reports. 10, 1, 11 p., 697.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Temporal dynamics and ecotoxicological risk assessment of personal care products, phthalate ester plasticizers, and organophosphorus flame retardants in water from Lake Victoria, Uganda
Nantaba, F., Palm, W. U., Wasswa, J., Bouwman, H., Kylin, H. & Kümmerer, K., 01.01.2021, In: Chemosphere. 262, 11 p., 127716.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Temporal variations of perfluoroalkyl substances and polybrominated diphenyl ethers in alpine snow
Kirchgeorg, T., Dreyer, A., Gabrieli, J., Kehrwald, N., Sigl, M., Schwikowski, M., Boutron, C., Gambaro, A., Barbante, C. & Ebinghaus, R., 01.07.2013, In: Environmental Pollution. 178, p. 367-374 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Tetrabutylammonium prolinate-based ionic liquids: A combined asymmetric catalysis, antimicrobial toxicity and biodegradation assessment
Ferlin, N., Courty, M., Van Nhien, A. N., Gatard, S., Pour, M., Quilty, B., Ghavre, M., Haiß, A., Kümmerer, K., Gathergood, N. & Bouquillon, S., 28.12.2013, In: RSC Advances. 3, 48, p. 26241-26251 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The 3 rd green & sustainable chemistry conference successfully brings together scientists and innovators from all over the world to discuss sustainable chemistry
Elschami, M. & Bazzanella, A., 02.2019, In: Current Opinion in Green and Sustainable Chemistry. 15, p. 115-117 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.
Ziegler, M., Elvers, M., Baumer, Y., Leder, C., Ochmann, C., Schönberger, T., Jürgens, T., Geisler, T., Schlosshauer, B., Lunov, O., Engelhardt, S., Simmet, T. & Gawaz, M., 07.02.2012, In: Circulation. 125, 5, p. 685-696 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The effect of storage medium on the elution of monomers from composite materials
Polydorou, O., Huberty, C., Wolkewitz, M., Bolek, R., Hellwig, E. & Kümmerer, K., 27.01.2012, In: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 100B, 1, p. 68-74 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The lipid composition of the in situ pellicle
Reich, M., Hannig, C., Hannig, M., Kümmerer, K. & Kensche, A., 01.10.2022, In: Archives of Oral Biology. 142, 105493.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The necessity of disinfected toilet brushes - information policy of companies on disinfectants in private homes
Wieck, S., 23.01.2015, In: Environmental Sciences Europe. 27, 1, 9 p., 3.Research output: Journal contributions › Journal articles › Research › peer-review