1. //
  2. Start
  3. //
  4. Publications
  5. //
  6. Octanol-Water Partition Coefficient Meas...
  7. //

Octanol-Water Partition Coefficient Measurement by a Simple 1H NMR Method

Research output: Journal contributions › Journal articles › Research › peer-review

Authors

We describe a simple miniature shake-flask method to measure the octanol-water partition coefficient of an organic compound. Partition between water and octanol is performed in an NMR tube; the aqueous phase is analyzed by 1H NMR spectroscopy using a benchtop low-field NMR instrument. Neither pre-equilibration of solvents nor isolation of the two phases is required. The procedure is fast and easy enough to be used in a students' laboratory. Scope and limitations as well as possible sources of error are discussed in detail.

Original languageEnglish
JournalACS Omega
Volume2
Issue number9
Pages (from-to)6244-6249
Number of pages6
ISSN2470-1343
DOIs
Publication statusPublished - 30.09.2017

Other publications by the same author(s)

Are Si-C bonds cleaved by microorganisms? A critical review on biodegradation of methylsiloxanes

Rücker, C., Grabitz, E. & Kümmerer, K., 01.04.2023, In: Chemosphere. 321, 137858.

Research output: Journal contributions › Journal articles › Research › peer-review

Are Si–C bonds formed in the environment and/or in technical microbiological systems?

Rücker, C., Winkelmann, M. & Kümmerer, K., 08.2023, In: Environmental Science and Pollution Research. 30, 39, p. 91492-91500 9 p.

Research output: Journal contributions › Journal articles › Research › peer-review

REACH und QSAR: ein Leitfaden für kleine und mittlere Unternehmen

Rücker, C., Mahmoud, W. M. M., Kümmerer, K. & Zipperer, U. (Editor), 06.2015, Lüneburg: Leuphana Universität Lüneburg, 29 p.

Research output: Working paper › Project reports › Research

Comment on "nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty?"

Rücker, C., Meringer, M. & Wassermann, A., 13.04.2021, In: Journal of Chemical Education. 98, 4, p. 1465-1467 3 p.

Research output: Journal contributions › Comments / Debate / Reports › Research

Environmental chemistry of organosiloxanes

Rücker, C. & Kümmerer, K., 14.01.2015, In: Chemical Reviews. 115, 1, p. 466-524 59 p.

Research output: Journal contributions › Scientific review articles › Research

DOI

Recently viewed

Activities

  1. Keep Calm and Solve the Problem: An Integrated Model to Reduce Threat and Defense in Conflicts
  2. Dimension theory of representations of real numbers
  3. The many paths one picture can paint: Tracing a visual’s boundary work
  4. Is a better understanding of assembly a way to help reassemble communities for restoration?
  5. Employer Longevity Readiness Index Workshop: Session 2: How do you build a longevity readiness Index?
  6. Computer Simulation as media of knowledge production in the practice of quantum theory
  7. Organized Creativity - Introduction to the 1st Annual Conference
  8. Intelligent software system for replacing a force sensor in the case of clearance measurement
  9. The link between in- and external rotation of the auditor and the quality of financial accounting and audit
  10. Learning to Rate Player Actions on the Example of Soccer
  11. MECS Conference: Dealing with Climate Change. Calculus & Catastrope in the Age of Simulation - 2015
  12. The Irish English discourse marker sure at the semantics/pragmatics interface
  13. Robots versus Machines

Publications

  1. Control system strategy of a modular omnidirectional AGV
  2. Scholarly Question Answering Using Large Language Models in the NFDI4DataScience Gateway
  3. Application of design of experiments for laser shock peening process optimization
  4. A survey of empirical studies using transaction level data on exports and imports
  5. A high-resolution approach for the spatiotemporal analysis of forest canopy space using terrestrial laser scanning data
  6. Das John-Stuart-Mill-Problem
  7. An integrative research framework for enabling transformative adaptation
  8. Errors in Working with Office Computers
  9. Complexity of traffic scenes and EEG-measures of processing workload in car driving
  10. Mirrored piezo servo hydraulic actuators for use in camless combustion engines and its Control with mirrored inputs and MPC
  11. Simple saturated PID control for fast transient of motion systems
  12. A Lyapunov based PI controller with an anti-windup scheme for a purification process of potable water
  13. Embarrassment as a public vs. private emotion and symbolic coping behaviour
  14. From "cracking the orthographic code" to "playing with language"
  15. Strategies of postural control in static and in dynamic testing situations
  16. Cost effectiveness of guided Internet-based interventions for depression in comparison with control conditions
  17. Adaptive control of the nonlinear dynamic behavior of the cantilever-sample system of an atomic force microscope
  18. Conjunctive cohesion in English language EU documents - A corpus-based analysis and its implications
  19. Effectiveness of a Web-Based Cognitive Behavioural Intervention for Subthreshold Depression
  20. Computational modeling of amorphous polymers
  21. Resolving the Complexity-Flexibility Dilemma in Multi-Issue Negotiations: Nested Bracketing as a Strategy to Enhance Negotiation Outcomes
  22. Discourse, practice, policy and organizing
  23. Developing a sustainable platform for entity annotation benchmarks
  24. Foreign bias in institutional portfolio allocation
  25. Preventive Diagnostics for cardiovascular diseases based on probabilistic methods and description logic
  26. Rethink Textile Production - Developing sustainable concepts for textile industry using production simulation
  27. Neural correlates of the enactment effect in the brain
  28. Recontextualizing Anthropomorphic Metaphors in Organization Studies
  29. Global fern and lycophyte richness explained: How regional and local factors shape plot richness
  30. A geometric approach to the decoupling control and to speed up the dynamics of a general rigid body manipulation system
  31. A Column Generation Approach for Bus Driver Rostering Problems
  32. The Lifecycle of "Facts'': A Survey of Social Bias in Knowledge Graphs
  33. Knowledge-Enhanced Language Models Are Not Bias-Proof