Use of lignins from sugarcane bagasse for assembling microparticles loaded with Azadirachta indica extracts for use as neem-based organic insecticides

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet


  • Eveline S. Costa
  • Bruno Perlatti
  • Everton M. Da Silva
  • Andreia P. Matos
  • Maria Fátima G.F. Da Silva
  • João B. Fernandes
  • Vânia G. Zuin
  • Caio M.P. Da Silva
  • Moacir R. Forim

Microcapsules of sugarcane bagasse lignin loaded with organic extracts of neem (Azadirachta indica) were prepared and evaluated as potential bioinsecticides. Lignins were extracted and modified by oxidation and acetylation reactions providing different biopolymers. Afterwards, they were characterized through several analytical techniques. The formulations were initially prepared as colloidal suspension of lignin nanoparticles, which were then spray-dried. The products were submitted to quality control protocols using high performance liquid chromatography (HPLC), thermal and photochemical degradation studies, followed by biological assays against Spodoptera frugiperda and Diatraea saccharalis. The formulations showed increases in both thermal and photo stability of approximately 40% compared with control samples. All the formulated microparticles were efficient against the insects evaluated and required a shorter time to achieve 100% mortality than the controls. The use of sugarcane bagasse lignins to prepare microparticles improved the resistance of neem extracts against abiotic factors, retaining the biological activity of this biopesticide.

ZeitschriftJournal of the Brazilian Chemical Society
Seiten (von - bis)126-135
Anzahl der Seiten10
PublikationsstatusErschienen - 01.01.2017
Extern publiziertJa

Bibliographische Notiz

Funding Information:
The authors would like to thank the CNPq (National Council of Technological and Scientific Development, 477051/2012-0; 301427/2012-7, 563063/2010-6), FAPESP (São Paulo Research Foundation 2011/11860-5; 2014/50827-1; 2011/00970-4; 2010/52312-8), INCT-Biorational Control of Plague Insects, CAPES (Coordination for the Improvement of Higher Level of Education Personnel), and Prof Edson Rodrigues Filho (LABioMMi) for support during several different projects.

Publisher Copyright:
©2017 Sociedade Brasileira de Química.