Multivariate Optimization of Analytical Methodology and a First Attempt to an Environmental Risk Assessment of β-Blockers in Hospital Wastewater

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Authors

This preliminary study evaluated an assessment of the risks arising from environmental exposure to β-blockers from wastewater of an university hospital (University Hospital of Santa Maria (HUSM), Rio Grande do Sul State, Brazil). Propranolol showed the highest risk quotient (0.56). The occurrence of β-blockers was evaluated using an analytical procedure SPE‑HPLC-FLD (solid phase extraction-high performance liquid chromatography with fluorescence detection), optimizing the variables sample pH, water pH, and methanol:acetonitrile:formic acid ratio of the elution stage. The average concentrations of atenolol, metoprolol and propranolol for a sampling period of one week were 2.45 ± 1.14, 4.67 ± 1.63 and 0.70 ± 0.88 μg L–1 in the ‘Emergence’ sewage; 0.95 ± 0.68, 0.70 ± 0.33 and 0.315 ± 0.62 μg L–1 in the ‘HUSM general’ sewage and 1.26 ± 0.47, 1.27 ± 0.35 and 0.56 ± 0.47 μg L–1 in the ‘Receiving waters’, the receptor stream of the effluents, respectively. Propranolol showed an MEC/PNEC ratio > 1, and thus requires more attention in terms of toxicity. The occurrence of β-blockers and the associated environmental risks demonstrate the need of a more efficient treatment system for the hospital wastewater.
OriginalspracheEnglisch
ZeitschriftJournal of the Brazilian Chemical Society
Jahrgang23
Ausgabenummer9
Seiten (von - bis)1732-1740
Anzahl der Seiten9
DOIs
PublikationsstatusErschienen - 25.09.2012

Dokumente

DOI

Zuletzt angesehen

Publikationen

  1. Ludic Interfaces
  2. machine/readable. Reflextions upon the ›knowledge‹ of images
  3. Explaining Age and Gender Differences in Employment Rates
  4. Synthesis of Room-Temperature Ionic Liquids with the Weakly Coordinating [Al(ORF)(4)](-) Anion (R-F = C(H)(CF3)(2)) and the Determination of Their Principal Physical Properties
  5. The impact of goal specificity and goal type on learning outcome and cognitive load
  6. In the Workshop of the Translator. Walter Benjamin in/on Translation
  7. Subsistence and substitutability in consumer preferences
  8. Predictive mapping of species richness and plant species' distributions of a peruvian fog oasis along an altitudinal gradient
  9. Digital Games and Fan-Discourse
  10. Turbulente Ränder
  11. Dialogue on Writing
  12. Not only biocidal products
  13. Multilevel Water Governance and Problems of Scale
  14. A Systematic Literature Review Of Machine Learning Approaches For The Prediction Of Delivery Dates
  15. Measuring institutional overlap in global governance
  16. The Shareholder Value Effect of System Overloads: An Analysis of Investor Responses to the 2003 Blackout in the US
  17. Fleck, Glanz, Finsternis
  18. Liquidity, Flows, Circulation
  19. Influence of Different Biogenic Fuels on Base Oil Aging
  20. Towards an agri-environment index for biodiversity conservation payment schemes
  21. Large, particular bovids may require localised conservation effort to prevent extinction
  22. Understanding and Communicating Climate Change in Metaphors
  23. Pathways to Reciprocated Friendships
  24. Contested World Order
  25. Learning in environmental governance: opportunities for translating theory to practice
  26. Is fairness intuitive? An experiment accounting for subjective utility differences under time pressure