Psychological treatment of generalized anxiety disorder: A meta-analysis
Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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in: Clinical Psychology Review, Jahrgang 34, Nr. 2, 03.2014, S. 130-140.
Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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TY - JOUR
T1 - Psychological treatment of generalized anxiety disorder
T2 - A meta-analysis
AU - Cuijpers, Pim
AU - Sijbrandij, Marit
AU - Koole, Sander L.
AU - Huibers, Marcus
AU - Berking, Matthias
AU - Andersson, Gerhard
PY - 2014/3
Y1 - 2014/3
N2 - Recent years have seen a near-doubling of the number of studies examining the effects of psychotherapies for generalized anxiety disorder (GAD) in adults. The present article integrates this new evidence with the older literature through a quantitative meta-analysis. A total of 41 studies (with 2132 patients meeting diagnostic criteria for GAD) were identified through systematic searches in bibliographical databases, and were included in the meta-analysis. Most studies examined the effects of cognitive behavior therapy (CBT). The majority of studies used waiting lists as control condition. The pooled effect of the 38 comparisons (from 28 studies) of psychotherapy versus a control group was large (g= 0.84; 95% CI: 0.71-0.97) with low to moderate heterogeneity. The effects based on self-report measures were somewhat lower than those based on clinician-rated instruments. The effects on depression were also large (g= 0.71; 95% CI: 0.59-0.82). There were some indications for publication bias. The number of studies comparing CBT with other psychotherapies (e.g., applied relaxation) or pharmacotherapy was too small to draw conclusions about comparative effectiveness or the long-term effects. There were some indications that CBT was also effective at follow-up and that CBT was more effective than applied relaxation in the longer term.
AB - Recent years have seen a near-doubling of the number of studies examining the effects of psychotherapies for generalized anxiety disorder (GAD) in adults. The present article integrates this new evidence with the older literature through a quantitative meta-analysis. A total of 41 studies (with 2132 patients meeting diagnostic criteria for GAD) were identified through systematic searches in bibliographical databases, and were included in the meta-analysis. Most studies examined the effects of cognitive behavior therapy (CBT). The majority of studies used waiting lists as control condition. The pooled effect of the 38 comparisons (from 28 studies) of psychotherapy versus a control group was large (g= 0.84; 95% CI: 0.71-0.97) with low to moderate heterogeneity. The effects based on self-report measures were somewhat lower than those based on clinician-rated instruments. The effects on depression were also large (g= 0.71; 95% CI: 0.59-0.82). There were some indications for publication bias. The number of studies comparing CBT with other psychotherapies (e.g., applied relaxation) or pharmacotherapy was too small to draw conclusions about comparative effectiveness or the long-term effects. There were some indications that CBT was also effective at follow-up and that CBT was more effective than applied relaxation in the longer term.
KW - Psychology
KW - Cognitive behavior therapy
KW - Comparative outcome studies
KW - Generalized anxiety disorder
KW - Meta-analysis
KW - Psychotherapy
KW - Randomized trial
UR - http://www.scopus.com/inward/record.url?scp=84893361841&partnerID=8YFLogxK
U2 - 10.1016/j.cpr.2014.01.002
DO - 10.1016/j.cpr.2014.01.002
M3 - Journal articles
C2 - 24487344
AN - SCOPUS:84893361841
VL - 34
SP - 130
EP - 140
JO - Clinical Psychology Review
JF - Clinical Psychology Review
SN - 0272-7358
IS - 2
ER -