Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- 2012
- Published
Gremlin fusion products with immunoglobulin Fc domains and their use as antiinflammatories or immunomodulators
Gawaz, M., Müller, I., Leder, C. & Filzmayer, C., 24.05.2012, IPC No. DE 102010052941A1, Deutsches Patent- und Markenamt, 18.11.2010, Priority date 24.05.2012Research output: Patents › Patent
- Published
Consequences of nuclear accidents for biodiversity and ecosystem services
von Wehrden, H., Fischer, J., Brandt, P., Wagner, V., Kümmerer, K., Kuemmerle, T., Nagel, A., Olsson, O. & Hostert, P., 01.04.2012, In: Conservation Letters. 5, 2, p. 81-89 9 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Bifunctional proteins as a therapeutic strategy for improved myocardial repair in cardiovascular diseases
Ziegler, M., Schönberger, T., Baumer, Y., Ochmann, C., Jürgens, T., Elvers, M., Leder, C., Schlosshauer, B. & Gawaz, M., 04.2012, Clin Res Cardiol: Suppl 1. Vol. 101. p. V1086 1 p.Research output: Contributions to collected editions/works › Article in conference proceedings › Research
- Published
Das Fettsäureprofil des initialen oralen Biofilms (Pellikel) - eine In-situ-Studie
Reich, M., Hannig, C., Al-Ahmad, A. & Kümmerer, K., 04.2012, In: Deutsche Zahnärztliche Zeitschrift. 67, 4, p. D18 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Modeling and predicting aquatic aerobic biodegradation: a review from a user’s perspective.
Rücker, C. & Kümmerer, K., 04.2012, In: Green Chemistry . 14, 4, p. 875-887 13 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Dynamische Modellierung der Sorption von Substanzen in einem hydrologischen Einzugsgebietsmodell anhand des Beispiels Phosphor
Gassmann, M. & Olsson, O., 22.03.2012, Wasser ohne Grenzen: Beiträge zum Tag der Hydrologie am 22./23. März 2012 an der Albert-Ludwigs-Universität Freiburg. Weiler, M. (ed.). 1 ed. Deutsche Vereinigung für Wasserwirtschaft, Abwasser und Abfall, 6 p. (Forum für Hydrologie und Wasserbewirtschaftung; vol. 31.12).Research output: Contributions to collected editions/works › Article in conference proceedings › Research
- Published
Degradation of the tricyclic antipsychotic drug chlorpromazine under environmental conditions, identification of its main aquatic biotic and abiotic transformation products by LC-MS n and their effects on environmental bacteria
Trautwein, C. & Kümmerer, K., 15.03.2012, In: Journal of Chromatography B. 889-890, p. 24-38 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Stand der Technik und fortschrittliche Ansätze in der Entsorgung des Flowback
Rosenwinkel, K-H., Weichgrebe, D. & Olsson, O., 07.03.2012, BerlinResearch output: other publications › Slides › Research
- Published
Nachhaltiges Ressourcen- und Stoffstrommanagement: Zwischen Gigatonnen und Mikrogramm
Bringezu, S. & Kümmerer, K., 03.2012, In: GAIA. 21, 1, p. 69–72 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.
Ziegler, M., Elvers, M., Baumer, Y., Leder, C., Ochmann, C., Schönberger, T., Jürgens, T., Geisler, T., Schlosshauer, B., Lunov, O., Engelhardt, S., Simmet, T. & Gawaz, M., 07.02.2012, In: Circulation. 125, 5, p. 685-696 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Nonylphenol polyethoxylate in hospital wastewater: A study of the subproducts of electrocoagulation
Henriques, D. M., Kümmerer, K., Mayer, F. M., Vasconcelos, T. G. & Martins, A. F., 01.02.2012, In: Journal of Environmental Science and Health, Part A. Toxic/Hazardous Substances and Environmental Engineering. 47, 3, p. 497-505 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The effect of storage medium on the elution of monomers from composite materials
Polydorou, O., Huberty, C., Wolkewitz, M., Bolek, R., Hellwig, E. & Kümmerer, K., 27.01.2012, In: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 100B, 1, p. 68-74 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Trends for snow cover and river flows in the Pamirs (Central Asia)
Chevallier, P., Pouyaud, B., Moja¨ısky, M., Bolgov, M., Olsson, O., Bauer, M. & Froebrich, J., 03.01.2012, In: Hydrology and Earth Systems Sciences Discussion. 9, p. 29–64 36 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradability and ecotoxicitiy of tramadol, ranitidine, and their photoderivatives in the aquatic environment: Biologische Abbaubarkeit und Ökotoxizität von Tramadol, Ranitidin sowie ihren Photoderivate in der aquatischen Umwelt
Bergheim, M., Gieré, R. & Kümmerer, K., 01.2012, In: Environmental Science and Pollution Research. 19, 1, p. 72-85 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Der Übergang ins Postfossile Zeitalter- Übersehene Knappheiten
Kümmerer, K., 01.2012, In: Tutzinger Blätter. B 13829, 1, p. 13-14 2 p.Research output: Journal contributions › Journal articles › Research
- Published
Künstliche Feuchtflächen in Hochwasserrückhaltebecken – eine Chance für die Reduzierung von Pflanzenschutzmitteleinträgen in Gewässer
Lange, J., Kümmerer, K., Imfeld, G., Herbstritt, B., Maillard, E., Lefrancq, M., Gutowski, L., Durst, R., Steudten, R., Regazzoni, C., Gassmann, M. & Payraudeau, S., 2012, Wasser ohne Grenzen: Beiträge zum Tag der Hydrologie am 22./23. März 2012 an der Albert-Ludwigs-Universität Freiburg. Weiler, M. (ed.). Deutsche Vereinigung für Wasserwirtschaft, Abwasser und Abfall, p. 293-298 6 p. (Forum für Hydrologie und Wasserbewirtschaftung; no. 38).Research output: Contributions to collected editions/works › Article in conference proceedings › Research
- Published
Photodegradation of thalidomide: Identification of transformation products by LC-UV-FL-MS/MS, assessment of biodegradability, cytotoxicity and mutagenicity.
Mahmoud, W. M. M., Toolaram, A. P., Schneider, M. & Kümmerer, K., 2012, 4th EuCheMS Chemistry Congress: Abstract book. Association of Czech Chemical Societies, Vol. 106. p. 650 1 p. (Chemické listy; vol. 106, no. S4).Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
Photolysis of sulfamethoxypyridazine in various aqueous media: Aerobic biodegradation and photoproducts identification by LC-UV-MS/MS
Khaleel, N. D. H., Mahmoud, W. M. M., Hadad, G. M., Abdel-Salam, R. A. & Kümmerer, K., 2012, In: Chemicke Listy. 106, S4, p. 904 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- 2011
- Published
Antibiotics in the Aquatic Environment
Kümmerer, K., 07.12.2011, Antimicrobial Resistance in the Environment. Keen, P. & Montforts, M. (eds.). 1. ed. Hoboken: John Wiley & Sons Ltd., p. 325-335 11 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
The use of a monolithic column to improve the simultaneous determination of caffeine, paracetamol, pseudoephedrine, aspirin, dextromethorphan, chlorpheniramine in pharmaceutical formulations by HPLC-A comparison with a conventional reversed-phase silica-based column
Hadad, G. M. & Mahmoud, W. M. M., 01.12.2011, In: Journal of Liquid Chromatography and Related Technologies. 34, 20, p. 2516–2532 17 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A Glance at the World
Sasu, S., Metzger, J., Kranert, M. & Kümmerer, K., 11.2011, In: Waste Management. 31, 11, p. 2361-2364 4 p.Research output: Journal contributions › Other (editorial matter etc.) › Research
- Published
Fusionsprotein und dessen Verwendungen
Leder, C., Gawaz, M., Ziegler, M. & Stellos, K., 06.10.2011, IPC No. DE 102010013887A1, Deutsches Patent- und Markenamt, 30.03.2010Research output: Patents › Patent
- Published
Release of monomers from four different composite materials after halogen and LED curing
Polydorou, O., König, A., Altenburger, M. J., Wolkewitz, M., Hellwig, E. & Kümmerer, K., 01.10.2011, In: American Journal of Dentistry. 24, 5, p. 315-321 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Emerging Contaminants versus Micro-pollutants
Kümmerer, K., 10.2011, In: Clean - Soil, Air, Water. 39, 10, p. 889–890 2 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
Trautwein, C. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 765-773 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes: Degradation, elucidation of byproducts and assessment of their biological potency
Fatta-Kassinos, D., Vasquez, M. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 693-709 17 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies
Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T. G., Gueutin, C., Guterres, S. S., Pohlmann, A. R. & Fattal, E., 21.08.2011, In: Soft Matter. 7, 16, p. 7304-7312 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identifizierung und Bewertung ausgewählter Arzneimittel und ihrer Metaboliten (Ab- und Umbauprodukte) im Wasserkreislauf
Kümmerer, K., Schuster, A., Längin, A., Happel, O., Thoma, A., Schneider, K., Hassauer, M., Gartiser, S. & Hafner, C., 01.08.2011, Dessau-Roßlau: Umweltbundesamt, 195 p. (Texte; vol. 46/2011).Research output: Working paper › Project reports › Transfer
- Published
Analyses of Drugs and Pharmaceuticals in the Environment
Ali, I., Aboul-Enein, H. Y. & Kümmerer, K., 05.07.2011, Biophysico-Chemical Processes of Anthropogenic Organic Compounds in Environmental Systems. Xing, B., Senesi, N. & Ming, P. (eds.). 1 ed. John Wiley & Sons Inc., p. 439-462 24 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Response to David B. Brooks
Wegerich, K. & Olsson, O., 05.2011, In: Water International. 36, 3, p. 410-413 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradability of organic nanoparticles in the aqueous environment
Kümmerer, K., Menz, J., Schubert, T. & Thielemans, W., 03.2011, In: Chemosphere. 82, 10, p. 1387-1392 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Modelling scenarios to identify a combined sediment-water management strategy for the large reservoirs of the Tuyamuyun hydro-complex
Olsson, O., Sorokin, A. & Ikramova, M., 03.2011, In: Irrigation and Drainage Systems. 25, 1, p. 1-18 18 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Bifunctional recombinant protein SDF1-GPVI as a new therapeutic concept for improved regeneration
Ziegler, M., Baumer, Y., Leder, C., Schönberger, T., Elvers, M., Schlosshauer, B. & Gawaz, M., 02.2011, BioStar 2010 - Science in Exchange: Meeting Abstracts. TERMIS, p. 553-554 2 p. (Tissue Engineering Part A; vol. 17, no. 3/4).Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
aCD133-GPVI: A bifunctional protein for imroved stent performance and endothelial regeneration
Baumer, Y., Leder, C., Schönberger, T., Ziegler, M., Filzmayer, C., Bühring, H-J. & Gawaz, M., 2011, In: Tissue Engineering Part A. 17, 3/4, p. 554 1 p.Research output: Journal contributions › Conference abstract in journal › Research
- 2010
- Published
Neuartige Spurenstoffe im Wasser
Kümmerer, K., 12.2010, In: Hydrologie und Wasserbewirtschaftung. 54, 6, p. 349-359 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Synthesis of Room-Temperature Ionic Liquids with the Weakly Coordinating [Al(ORF)(4)](-) Anion (R-F = C(H)(CF3)(2)) and the Determination of Their Principal Physical Properties
Bulut, S., Klose, P., Huang, M-M., Weingartner, H., Dyson, P. J., Laurenczy, G., Friedrich, C., Menz, J., Kummerer, K. & Krossing, I., 22.11.2010, In: Chemistry - A European Journal. 16, 44, p. 13139-13154 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Late developers and the inequity of "equitable utilization" and the harm of "do no harm"
Wegerich, K. & Olsson, O., 11.2010, In: Water International. 35, 6, p. 707-717 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inhibition of foam cell formation using a soluble CD68-Fc fusion protein
Daub, K., Siegel-Axel, D., Schönberger, T., Leder, C., Seizer, P., Müller, K., Schaller, M., Penz, S., Menzel, D., Buchele, B., Bültmann, A., Münch, G., Lindemann, S., Simmet, T. & Gawaz, M., 09.2010, In: Journal of Molecular Medicine. 88, 9, p. 909-920 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
1002 Pharmacokinetic studies on a novel HBV entry inhibitor Myrcludex B demonstrate HBV-receptor expression in rodents and dogs but not in cynomolgus monkeys
Schieck, A., Meier, A., Alexandrov, A., Leder, C., Romeis, P., Haberkorn, U., Mier, J. W. & Urban, S., 01.04.2010, In: Journal of Hepatology. 51, 1, p. S387 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Modulating immune responses and inflammation
Leder, C., Ziegler, M. & Gawaz, M., 03.2010, In: Seminars in Thrombosis and Hemostasis. 36, 2, p. 219-222 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Environmental impacts of droughts: key challenges.
Olsson, O., 23.02.2010, BrüsselResearch output: other publications › Slides › Research
- Published
Applicability of adapted reservoir operation for water stress mitigation under dry year conditions
Olsson, O., Ikramova, M., Bauer, M. & Froebrich, J., 01.2010, In: Water Resources Management. 24, 2, p. 277-297 21 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Interstate Water Resource Risk Management: Towards a Sustainable Future for the Aral Basin (JAYHUN)
Olsson, O. (ed.) & Bauer, M. (ed.), 2010, London: IWA Publishing. 121 p.Research output: Books and anthologies › Collected editions and anthologies › Research
- 2009
- Published
Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 12.2009, In: Chromatographia. 70, 11/12, p. 1593–1598 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Development and validation of a stability-indicating RP-HPLC method for the determination of paracetamol with dantrolene or/and cetirizine and pseudoephedrine in two pharmaceutical dosage forms
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 15.10.2009, In: Talanta. 79, 5, p. 1360-1367 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Rapid Identification of Bacteria in Clinical Microbiology Routiine Diagnostics using MALDI-TOF mass spectrometry
Reich, M., Stark, M., Huesgen, G., Beyser, K. & Borgmann, S., 01.09.2009, In: International Journal of Medical Microbiology. 299, Supplement 1, p. 3 1 p., DVP 11.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans
Scholtka, B., Schneider, M., Melcher, R., Katzenberger, T., Friedrich, D., Berghof-Jäger, K., Scheppach, W. & Steinberg, P., 08.2009, In: Cancer Epidemiology. 33, 2, p. 123-129 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Jayhun - Grenzüberschreitendes Wasserressourcenmanagement des Amu Darya für eine nachhaltige Zukunft im Aralseebecken
Olsson, O., 08.2009, In: Hydrologie und Wasserbewirtschaftung. 53, 4, p. 271-272 2 p.Research output: Journal contributions › Journal articles › Research
- Published
Enhanced reservoir operation as an instrument for supporting water stress mitigation: the Italian case study.
Bauer, M., Botti, P., Zaccolo, S. & Olsson, O., 10.06.2009, The Use of Economic Valuation in Environmental Policy: Providing Research Support for the Implementation of EU Water Policy Under Aquastress. Koundouri, P. (ed.). 1 ed. London: Routledge Taylor & Francis Group, p. 196-220 25 p. (Routledge explorations in environmental economics; no. 17).Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Biomonitoring Hospital Effluents by the Allium cepa L. Test
Bagatini, M. D., Vasconcelos, T. G., Laughinghouse IV, H. D. & Martins, A. F., 05.2009, In: Bulletin of Environmental Contamination and Toxicology. 82, 5, p. 590-592 3 p.Research output: Journal contributions › Journal articles › Research › peer-review