Efficacy and cost-effectiveness of a web-based intervention with mobile phone support to treat depressive symptoms in adults with diabetes mellitus type 1 and type 2: Design of a randomised controlled trial

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Standard

Harvard

APA

Vancouver

Bibtex

@article{92ded0e8a7a94b0e973b524f4bd32104,
title = "Efficacy and cost-effectiveness of a web-based intervention with mobile phone support to treat depressive symptoms in adults with diabetes mellitus type 1 and type 2: Design of a randomised controlled trial",
abstract = "Background: A diagnosis of diabetes mellitus types 1 or 2 doubles the odds of a comorbid depressive disorder. The combined diseases have a wide range of adverse outcomes, such as a lower quality of life, poorer diabetes outcomes and increased healthcare utilisation. Diabetes patients with depression can be treated effectively with psychotherapy, but access to psychological care is limited. In this study we will examine the efficacy and cost-effectiveness of a newly developed web-based intervention (GET.ON Mood Enhancer Diabetes) for people with diabetes and comorbid depressive symptoms.Methods/Design: A two-arm randomised controlled trial will be conducted. Adults with diabetes (type 1 or type 2) with increased depression scores (> 22 on the German version of the Center for Epidemiological Studies Depression Scale (CES-D)) will be included. Eligible participants will be recruited through advertisement in diabetes patient journals and via a large-scale German health insurance company. The participants will be randomly assigned to either a 6-week minimally guided web-based self-help program or an online psychoeducation program on depression. The study will include 260 participants, which will enable us to detect a statistically significant difference with a group effect size of d = 0.35 at a power of 80% and a significance level of p = 0.05. The primary outcome measure will be the level of depression as assessed by the CES-D. The secondary outcome measures will be: diabetes-specific emotional distress, glycaemic control, self-management behaviour and the participants' satisfaction with the intervention. Online self-assessments will be collected at baseline and after a 2 months period, with additional follow-up measurements 6 and 12 months after randomisation. The data will be analysed on an intention-to-treat basis and per protocol. In addition, we will conduct an economic evaluation from a societal perspective.Discussion: If this intervention is shown to be cost-effective, it has considerable potential for implementing psychological care for large numbers of people with diabetes and comorbid depression in routine practice and improve health outcomes.Trial registration: German Clinical Trial Register (DRKS): DRKS00004748.",
keywords = "Health sciences, Diabetes mellitus, Cost-effectiveness, Depression, Diabetes, Efficacy, Guided web-based self-help, Internet, Randomised controlled trial, Psychology, depressive Symptome, internetbasierte Therapie, web-basierte Intervention",
author = "Stephanie Nobis and Dirk Lehr and Ebert, {David Daniel} and Matthias Berking and Elena Heber and Harald Baumeister and Annette Becker and Frank Snoek and Heleen Riper",
year = "2013",
month = nov,
day = "15",
doi = "10.1186/1471-244X-13-306",
language = "English",
volume = "13",
journal = "BMC Psychiatry",
issn = "1471-244X",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Efficacy and cost-effectiveness of a web-based intervention with mobile phone support to treat depressive symptoms in adults with diabetes mellitus type 1 and type 2

T2 - Design of a randomised controlled trial

AU - Nobis, Stephanie

AU - Lehr, Dirk

AU - Ebert, David Daniel

AU - Berking, Matthias

AU - Heber, Elena

AU - Baumeister, Harald

AU - Becker, Annette

AU - Snoek, Frank

AU - Riper, Heleen

PY - 2013/11/15

Y1 - 2013/11/15

N2 - Background: A diagnosis of diabetes mellitus types 1 or 2 doubles the odds of a comorbid depressive disorder. The combined diseases have a wide range of adverse outcomes, such as a lower quality of life, poorer diabetes outcomes and increased healthcare utilisation. Diabetes patients with depression can be treated effectively with psychotherapy, but access to psychological care is limited. In this study we will examine the efficacy and cost-effectiveness of a newly developed web-based intervention (GET.ON Mood Enhancer Diabetes) for people with diabetes and comorbid depressive symptoms.Methods/Design: A two-arm randomised controlled trial will be conducted. Adults with diabetes (type 1 or type 2) with increased depression scores (> 22 on the German version of the Center for Epidemiological Studies Depression Scale (CES-D)) will be included. Eligible participants will be recruited through advertisement in diabetes patient journals and via a large-scale German health insurance company. The participants will be randomly assigned to either a 6-week minimally guided web-based self-help program or an online psychoeducation program on depression. The study will include 260 participants, which will enable us to detect a statistically significant difference with a group effect size of d = 0.35 at a power of 80% and a significance level of p = 0.05. The primary outcome measure will be the level of depression as assessed by the CES-D. The secondary outcome measures will be: diabetes-specific emotional distress, glycaemic control, self-management behaviour and the participants' satisfaction with the intervention. Online self-assessments will be collected at baseline and after a 2 months period, with additional follow-up measurements 6 and 12 months after randomisation. The data will be analysed on an intention-to-treat basis and per protocol. In addition, we will conduct an economic evaluation from a societal perspective.Discussion: If this intervention is shown to be cost-effective, it has considerable potential for implementing psychological care for large numbers of people with diabetes and comorbid depression in routine practice and improve health outcomes.Trial registration: German Clinical Trial Register (DRKS): DRKS00004748.

AB - Background: A diagnosis of diabetes mellitus types 1 or 2 doubles the odds of a comorbid depressive disorder. The combined diseases have a wide range of adverse outcomes, such as a lower quality of life, poorer diabetes outcomes and increased healthcare utilisation. Diabetes patients with depression can be treated effectively with psychotherapy, but access to psychological care is limited. In this study we will examine the efficacy and cost-effectiveness of a newly developed web-based intervention (GET.ON Mood Enhancer Diabetes) for people with diabetes and comorbid depressive symptoms.Methods/Design: A two-arm randomised controlled trial will be conducted. Adults with diabetes (type 1 or type 2) with increased depression scores (> 22 on the German version of the Center for Epidemiological Studies Depression Scale (CES-D)) will be included. Eligible participants will be recruited through advertisement in diabetes patient journals and via a large-scale German health insurance company. The participants will be randomly assigned to either a 6-week minimally guided web-based self-help program or an online psychoeducation program on depression. The study will include 260 participants, which will enable us to detect a statistically significant difference with a group effect size of d = 0.35 at a power of 80% and a significance level of p = 0.05. The primary outcome measure will be the level of depression as assessed by the CES-D. The secondary outcome measures will be: diabetes-specific emotional distress, glycaemic control, self-management behaviour and the participants' satisfaction with the intervention. Online self-assessments will be collected at baseline and after a 2 months period, with additional follow-up measurements 6 and 12 months after randomisation. The data will be analysed on an intention-to-treat basis and per protocol. In addition, we will conduct an economic evaluation from a societal perspective.Discussion: If this intervention is shown to be cost-effective, it has considerable potential for implementing psychological care for large numbers of people with diabetes and comorbid depression in routine practice and improve health outcomes.Trial registration: German Clinical Trial Register (DRKS): DRKS00004748.

KW - Health sciences

KW - Diabetes mellitus

KW - Cost-effectiveness

KW - Depression

KW - Diabetes

KW - Efficacy

KW - Guided web-based self-help

KW - Internet

KW - Randomised controlled trial

KW - Psychology

KW - depressive Symptome

KW - internetbasierte Therapie

KW - web-basierte Intervention

UR - http://www.scopus.com/inward/record.url?scp=84887544960&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/2652a7de-63a0-3524-9011-f9aa8b6caad5/

U2 - 10.1186/1471-244X-13-306

DO - 10.1186/1471-244X-13-306

M3 - Journal articles

C2 - 24238346

VL - 13

JO - BMC Psychiatry

JF - BMC Psychiatry

SN - 1471-244X

M1 - 306

ER -

Dokumente

DOI

Zuletzt angesehen

Aktivitäten

  1. Ich sehe was, was du nicht siehst: Die Rolle der Wahrnehmung alter(n)sfreundlicher Führung und Arbeitsgestaltung durch Führungskräfte für das Wohlbefinden älterer Beschäftigter
  2. 11. Arbeitstagung der Fachgruppe Differentielle Psychologie, Persönlichkeitspsychologie und Psychologische Diagnostik der Deutschen Gesellschaft für Psychologie - DGPs DPPD 2011
  3. Die Erstellung von evidenzbasierten Behandlungspfaden zur ambulanten Versorgung von Menschen mit einer psychischen Störung: Welche methodischen Fallstricke gilt es zu beachten?
  4. Multiprofessionelle Zusammenarbeit in Entwicklungsteams im Projekt Zukunftszentrum Lehrkräftebildung - Netzwerk (ZZL-Netzwerk): Ziele - Meilensteine - ausgewählte Forschungsergebnisse
  5. Presentation of the paper entitled "Conception and analysis of Cascaded Dual Kalman Filters as virtual sensors for mastication activity of stomatognathic craniomandibular system"
  6. Zvil(haftungs-)rechtliche und strafrechtliche Aspekte von Schadensfällen im Bereich der pränatalen Vorsorge und die Bedeutung des medizinischen Sachverständigengutachtens bei Gericht
  7. Weltbild und Nachhaltigkeit - Sumak kawsay, ubuntu, sejahtera: Wie lassen sich traditionelle Weltbilder und Kosmovisionen und die Globale Nachhaltigkeitsagenda (2030) aufeinander beziehen?
  8. Corporate social responsibility performance, reporting and generalized methods of moments (GMM): A structured review of corporate governance determinants and firms’ financial consequences
  9. Soziale Arbeit und soziale Frage(n):Jahrestagung der ÖFEB-Sektion Sozialpädagogik: Die Konstruktion von Patenschaften für „unbegleitete minderjährige Flüchtlinge“. Eine Bearbeitung neuer sozialer Fragen.

Publikationen

  1. Effectiveness of a Guided Internet- and Mobile-Based Intervention for Patients with Chronic Back Pain and Depression (WARD-BP): A Multicenter, Pragmatic Randomized Controlled Trial
  2. Enhancing the structural diversity between forest patches — A concept and real-world experiment to study biodiversity, multifunctionality and forest resilience across spatial scales
  3. Performance of the Chemcatcher ® passive sampler when used to monitor 10 polar and semi-polar pesticides in 16 Central European streams, and comparison with two other sampling methods
  4. Burdens, Stresses, Resources and Needs of School Management and Teaching staff during the Corona Pandemic. Results of a qualitative Interview Study at primary and secondary Schools in Hesse
  5. Cross-level Information and Influence in Mandated Participatory Planning: Alternative Pathways to Sustainable Water Management in Germany’s Implementation of the EU Water Framework Directive
  6. Michael Lichtblau, Daniel Blömer u.a. (Hrsg.): Forschung zu inklusiver Bildung.Gemeinsam anders lehren und lernen. Julius Klinkhardt Verlagsbuchhandlung (Bad Heilbrunn) 2014. 361 Seiten. ISBN 978-3-7815-1986-2.
  7. Comparative effectiveness of guided internet-based stress management training versus established in-person group training in employees – study protocol for a pragmatic, randomized, non-inferiority trial
  8. REGIONALE VERSORGUNGSSTRUKTUR IM BEREICH DER SUCHTKRANKENHILFE. MODELL EINES GEMEINDENAHEN VERSORGUNGSSYSTEMS UND ERGEBNISSE AUS EINER EMPIRISCHEN UNTERSUCHUNG BEZOGEN AUF STADT UND LANDKREIS LUNEBURG
  9. Erfassung der gesundheitsfördernden Schule: Erste methodische Erfahrungen mit dem SEP-Modul „Gesundheitsförderung“ im Rahmen der Evaluation des Landesprogramms für eine gute gesunde Schule im Land Brandenburg
  10. BESUB III – Zur Beschreibung der Sichtstrukturen kaufmännischen Unterrichts entlang von Sozialformen und Unterrichtsphasen - Ergebnisse einer vertiefenden Analyse mit einem ausdifferenzierten Erhebungsinstrument
  11. A three-armed randomised controlled trial investigating the comparative impact of guidance on the efficacy of a web-based stress management intervention and health impairing and promoting mechanisms of prevention