Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Chapter › Research › Peer-reviewed
- Published
Analyses of Drugs and Pharmaceuticals in the Environment
Ali, I., Aboul-Enein, H. Y. & Kümmerer, K., 05.07.2011, Biophysico-Chemical Processes of Anthropogenic Organic Compounds in Environmental Systems. Xing, B., Senesi, N. & Ming, P. (eds.). 1 ed. John Wiley & Sons Inc., p. 439-462 24 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Antibiotics in the Aquatic Environment
Kümmerer, K., 07.12.2011, Antimicrobial Resistance in the Environment. Keen, P. & Montforts, M. (eds.). 1. ed. Hoboken: John Wiley & Sons Ltd., p. 325-335 11 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Benign by design: Benign by Design
Kümmerer, K., 14.03.2016, Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry. Summerton, L., Sneddon, H. F., Jones, L. C. & Clark, J. H. (eds.). Cambridge: Royal Society of Chemistry, p. 73-81 9 p. (RSC Green Chemistry; vol. 2016-January, no. 46).Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Enhanced reservoir operation as an instrument for supporting water stress mitigation: the Italian case study.
Bauer, M., Botti, P., Zaccolo, S. & Olsson, O., 10.06.2009, The Use of Economic Valuation in Environmental Policy: Providing Research Support for the Implementation of EU Water Policy Under Aquastress. Koundouri, P. (ed.). 1 ed. London: Routledge Taylor & Francis Group, p. 196-220 25 p. (Routledge explorations in environmental economics; no. 17).Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Green chemistry and its contribution to industrial biotechnology
Pleissner, D. & Kümmerer, K., 2020, Sustainability and Life Cycle Assessment in Industrial Biotechnology. Fröhling, M. & Hiete, M. (eds.). Cham: Springer International Publishing AG, p. 281-298 18 p. (Advances in Biochemical Engineering/Biotechnology; vol. 173).Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Metabolites and Transformation Products of Pharmaceuticals in the Aquatic Environment as Contaminants of Emerging Concern
Michael, I., Vasquez Hadjilyra, M. I., Hapeshi, E., Haddad, T., Baginska, E., Kümmerer, K. & Fatta-Kassinos, D., 01.01.2014, Transformation Products of Emerging Contaminants in the Environment: Analysis, Processes, Occurrence, Effects and Risks. Lambropoulou, D. A. & Nollet, L. M. (eds.). Chichester: Wiley-VCH Verlag, p. 413-458 46 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Presence, fate and risks of pharmaceuticals in the environment
Kümmerer, K., 14.03.2016, Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry. Summerton, L., Sneddon, H. F., Jones, L. C. & Clark, J. H. (eds.). Cambridge: Royal Society of Chemistry, p. 63-72 10 p. (RSC Green Chemistry; vol. 2016-January, no. 46).Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
Sustainable Chemistry - Path and Goal for a More Sustainable Textile Sector
Kümmerer, K. & Keßler, L., 25.10.2020, Sustainable Textile and Fashion Value Chains: Drivers, Concepts, Theories and Solutions. Matthes, A., Beyer, K., Cebulla, H., Arnold, M. G. & Schumann, A. (eds.). Cham: Springer Nature AG, p. 75-104 30 p.Research output: Contributions to collected editions/works › Chapter › peer-review
- Published
The Education, Research, Society, and Policy Nexus of Sustainable Water Use in Semiarid Regions - A Case Study from Tunisia
Mader, C., Mahjoub, B., Bressler, K., Jebari, S., Kümmerer, K., Bahadir, M. & Leitenberger, A-T., 2015, Sustainable Water Use and Management: examples of new approaches and perspectives. Leal Filho, W. & Sümer, V. (eds.). Cham: Springer International Publishing AG, p. 277-291 15 p. (Green Energy and Technology).Research output: Contributions to collected editions/works › Chapter › peer-review
- Comments / Debate / Reports › Research
- Published
Chemistry and materials science for a sustainable circular polymeric economy
Zuin Zeidler, V. G. & Kümmerer, K., 01.02.2022, In: Nature Reviews Materials. 7, 2, p. 76-78 3 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Comment on "nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty?"
Rücker, C., Meringer, M. & Wassermann, A., 13.04.2021, In: Journal of Chemical Education. 98, 4, p. 1465-1467 3 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Emerging Contaminants versus Micro-pollutants
Kümmerer, K., 10.2011, In: Clean - Soil, Air, Water. 39, 10, p. 889–890 2 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
One planet: one health. A call to support the initiative on a global science–policy body on chemicals and waste
Brack, W., Barcelo Culleres, D., Boxall, A. B. A., Budzinski, H., Castiglioni, S., Covaci, A., Dulio, V., Escher, B. I., Fantke, P., Kandie, F., Fatta-Kassinos, D., Hernández, F. J., Hilscherová, K., Hollender, J., Hollert, H., Jahnke, A., Kasprzyk-Hordern, B., Khan, S. J., Kortenkamp, A., Kümmerer, K., Lalonde, B., Lamoree, M. H., Levi, Y., Lara Martín, P. A., Montagner, C. C., Mougin, C., Msagati, T., Oehlmann, J., Posthuma, L., Reid, M., Reinhard, M., Richardson, S. D., Rostkowski, P., Schymanski, E., Schneider, F., Slobodnik, J., Shibata, Y., Snyder, S. A., Fabriz Sodré, F., Teodorovic, I., Thomas, K. V., Umbuzeiro, G. A., Viet, P. H., Yew-Hoong, K. G., Zhang, X. & Zuccato, E., 01.12.2022, In: Environmental Sciences Europe. 34, 1, 10 p., 21.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Repurposing chemical waste: Sustainable chemistry for circularity beyond artificial intelligence
Zuin, V. G. & Kümmerer, K., 21.07.2022, In: Cell. 185, 15, p. 2655-2656 2 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Towards more sustainable curricula
Zuin, V. G. & Kümmerer, K., 01.02.2021, In: Nature Reviews Chemistry. 5, 2, p. 76-77 2 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Book › Research
- Published
Mathematical Chemistry and Chemoinformatics: Structure Generation, Elucidation and Quantitative Structure-Property Relationships
Kerber, A., Laue, R., Meringer, M., Rücker, C. & Schymanski, E., 01.01.2014, 1 ed. Berlin: Walter de Gruyter GmbH. 521 p.Research output: Books and anthologies › Book
- Project reports › Transfer
- Published
Identifizierung und Bewertung ausgewählter Arzneimittel und ihrer Metaboliten (Ab- und Umbauprodukte) im Wasserkreislauf
Kümmerer, K., Schuster, A., Längin, A., Happel, O., Thoma, A., Schneider, K., Hassauer, M., Gartiser, S. & Hafner, C., 01.08.2011, Dessau-Roßlau: Umweltbundesamt, 195 p. (Texte; vol. 46/2011).Research output: Working paper › Project reports › Transfer
- Project reports › Research
- Published
REACH und QSAR: ein Leitfaden für kleine und mittlere Unternehmen
Rücker, C., Mahmoud, W. M. M., Kümmerer, K. & Zipperer, U. (ed.), 06.2015, Lüneburg: Leuphana Universität Lüneburg, 29 p.Research output: Working paper › Project reports › Research
- Expert opinions › Transfer
- Published
Arzneimittelrückstände in Trinkwasser und Gewässern: Endbericht zum TA-Projekt
Klauer, B., Aicher, C., Bratan, T., Eberle, U., Hillenbrand, T., Kümmerer, K., Reuter, W., Schiller, J., Schulte-Römer, N., Schramm, E., Tettenborn, F., Völker, C. & Walz, A., 09.01.2020, Köln: Bundesanzeiger Verlag, 146 p. (TAB-Arbeitsbericht ; no. 183)(Verhandlungen des Deutschen Bundestages. Drucksachen; no. 19/16430).Research output: Working paper › Expert opinions
- Patent › Transfer
- Published
Biologisch abbaubare Chinolon-Antibiotika
Kümmerer, K., Leder, C., Rastogi, T., Suk, M. & Menz, J., 11.04.2019, IPC No. A61K31/47 , A61P31/04 , C07D215/233, C07D215/38 , C07D403/12, C07D401/12, Y02A50/30, Europäisches Patentamt, Patent No. DE102017218114A1, 11.10.2017, Priority date 11.10.2017, Priority No. DE102017218114AResearch output: Patents › Patent
- Published
BIOLOGISCH ABBAUBARE CHINOLON-ANTIBIOTIKA
Kümmerer, K., Leder, C., Rastogi, T., Suk, M. & Menz, J., 19.08.2020, IPC No. A61K31/4709 , A61P31/04 , C07D401/12, Europäisches Patentamt, Patent No. EP3694516A1, 10.10.2018, Priority date 11.10.2017, Priority No. DE102017218114AResearch output: Patents › Patent
- Published
Fusionsprotein und dessen Verwendungen
Leder, C., Gawaz, M., Ziegler, M. & Stellos, K., 06.10.2011, IPC No. DE 102010013887A1, Deutsches Patent- und Markenamt, 30.03.2010Research output: Patents › Patent
- Published
Gremlin fusion products with immunoglobulin Fc domains and their use as antiinflammatories or immunomodulators
Gawaz, M., Müller, I., Leder, C. & Filzmayer, C., 24.05.2012, IPC No. DE 102010052941A1, Deutsches Patent- und Markenamt, 18.11.2010, Priority date 24.05.2012Research output: Patents › Patent
- Published
IN DER UMWELT ABBAUBARE CHINOLON-ANTIBIOTIKA MIT HEMIAMINAL-STRUKTUREINHEIT
Kümmerer, K., Leder, C., Rastogi, T., Suk, M. & Peifer, C., 18.04.2019, IPC No. A61K31/47, A61P31/04 , C07D405/06, Europäisches Patentamt, Patent No. WO2019072905A1, 10.10.2018, Priority date 11.10.2017, Priority No. DE102017218119AResearch output: Patents › Patent
- Published
Methods and compositions relating to a vaccine against prostate cancer
Leder, C., King, A. D., Pavlenko, M. & Pisa, P., 04.01.2007, IPC No. A61K39/00 (2006.01), Patent No. WO/2007/002149 A2, 21.06.2006Research output: Patents › Patent
- Published
Random peptide library displayed on AAV vectors targeting human primary coronary artery endothelial cells
Kleinschmidt, J., Müller, O., Trepel, M., Kaul, F. & Leder, C., 30.09.2004, IPC No. C12N 15/10 (2006.01), PCT/EP2004/002923 , WIPO - Weltorganisation für geistiges Eigentum, Patent No. WO 2004083441, 19.03.2004, Priority date 19.03.2003Research output: Patents › Patent
- Slides › Research
- Published
Environmental impacts of droughts: key challenges.
Olsson, O., 23.02.2010, BrüsselResearch output: other publications › Slides › Research
- Published
Stand der Technik und fortschrittliche Ansätze in der Entsorgung des Flowback
Rosenwinkel, K-H., Weichgrebe, D. & Olsson, O., 07.03.2012, BerlinResearch output: other publications › Slides › Research
- Conference article in journal › Research › Peer-reviewed
- Published
Reaction of Calcium Chloride and Magnesium Chloride and their Mixed Salts with Ethanol for Thermal Energy Storage
Korhammer, K., Apel, C., Osterland, T. & Ruck, W. K. L., 01.06.2016, In: Energy Procedia. 91, p. 161-171 11 p., 125043.Research output: Journal contributions › Conference article in journal › Research › peer-review
- Conference abstract in journal › Research › Peer-reviewed
- Published
1002 Pharmacokinetic studies on a novel HBV entry inhibitor Myrcludex B demonstrate HBV-receptor expression in rodents and dogs but not in cynomolgus monkeys
Schieck, A., Meier, A., Alexandrov, A., Leder, C., Romeis, P., Haberkorn, U., Mier, J. W. & Urban, S., 01.04.2010, In: Journal of Hepatology. 51, 1, p. S387 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Das Fettsäureprofil des initialen oralen Biofilms (Pellikel) - eine In-situ-Studie
Reich, M., Hannig, C., Al-Ahmad, A. & Kümmerer, K., 04.2012, In: Deutsche Zahnärztliche Zeitschrift. 67, 4, p. D18 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Ecotoxicological evaluation of selected anticancer drugs
Lutterbeck, C., Kern, D. I., Machado, Ê. L. & Kümmerer, K., 10.09.2014, In: Toxicology Letters. 229, Supplement, p. S71-S72 2 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Evaluation of the effects of four cytotoxic compounds against plant seedlings
Lutterbeck, C., Kern, D. I., Machado, Ê. L. & Kümmerer, K., 10.09.2014, In: Toxicology Letters. 229, Supplement, p. S71-S71 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Intentionelle Modifizierung des Lipidprofils des initialen oralen Biofilms durch Mundspülung mit Leinöl
Reich, M., Kümmerer, K., Robertson, J., Hannig, M. & Hannig, C., 2017, In: Deutsche Zahnärztliche Zeitschrift. 72, S, p. D8 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Photolysis of sulfamethoxypyridazine in various aqueous media: Aerobic biodegradation and photoproducts identification by LC-UV-MS/MS
Khaleel, N. D. H., Mahmoud, W. M. M., Hadad, G. M., Abdel-Salam, R. A. & Kümmerer, K., 2012, In: Chemicke Listy. 106, S4, p. 904 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Rapid Identification of Bacteria in Clinical Microbiology Routiine Diagnostics using MALDI-TOF mass spectrometry
Reich, M., Stark, M., Huesgen, G., Beyser, K. & Borgmann, S., 01.09.2009, In: International Journal of Medical Microbiology. 299, Supplement 1, p. 3 1 p., DVP 11.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Conference abstract in journal › Research › Not peer-reviewed
- Published
aCD133-GPVI: A bifunctional protein for imroved stent performance and endothelial regeneration
Baumer, Y., Leder, C., Schönberger, T., Ziegler, M., Filzmayer, C., Bühring, H-J. & Gawaz, M., 2011, In: Tissue Engineering Part A. 17, 3/4, p. 554 1 p.Research output: Journal contributions › Conference abstract in journal › Research
- Scientific review articles › Research
- Published
A path to clean water: Reduced chemicals input must complement wastewater treatment to ensure the safety of water resources
Kümmerer, K., Dionysiou, D. D., Olsson, O. & Fatta-Kassinos, D., 20.07.2018, In: Science. 361, 6399, p. 222 - 224 3 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Application of titanium dioxide nanoparticles as a photocatalyst for the removal of micropollutants such as pharmaceuticals from water
Mahmoud, W. M. M., Rastogi, T. & Kümmerer, K., 01.08.2017, In: Current Opinion in Green and Sustainable Chemistry. 6, p. 1-10 10 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Consequences of nuclear accidents for biodiversity and ecosystem services
von Wehrden, H., Fischer, J., Brandt, P., Wagner, V., Kümmerer, K., Kuemmerle, T., Nagel, A., Olsson, O. & Hostert, P., 01.04.2012, In: Conservation Letters. 5, 2, p. 81-89 9 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Emerging risks from ballast water treatment: The run-up to the International Ballast Water Management Convention
Werschkun, B., Banerji, S., Basurko, O. C., David, M., Fuhr, F., Gollasch, S., Grummt, T., Haarich, M., Jha, A. N., Kacan, S., Kehrer, A., Linders, J., Mesbahi, E., Pughiuc, D., Richardson, S. D., Schwarz-Schulz, B., Shah, A., Theobald, N., von Gunten, U., Wieck, S. & Höfer, T., 01.10.2014, In: Chemosphere. 112, p. 256-266 11 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental chemistry of organosiloxanes
Rücker, C. & Kümmerer, K., 14.01.2015, In: Chemical Reviews. 115, 1, p. 466-524 59 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental risk assessment of anti-cancer drugs and their transformation products: a focus on their genotoxicity characterization-state of knowledge and short comings
Toolaram, A. P., Kümmerer, K. & Schneider, M., 04.2014, In: Mutation Research. 760, p. 18-35 18 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental side effects of pharmaceutical cocktails: What we know and what we should know
Vasquez, M. I., Lambrianides, A., Schneider, M., Kümmerer, K. & Fatta-Kassinos, D., 30.08.2014, In: Journal of Hazardous Materials. 279, p. 169-189 21 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Flavonoids as biopesticides – Systematic assessment of sources, structures, activities and environmental fate
Schnarr, L., Segatto, M. L., Olsson, O., Zuin, V. G. & Kümmerer, K., 10.06.2022, In: Science of the Total Environment. 824, 153781.Research output: Journal contributions › Scientific review articles › Research
- Published
From a problem to a business opportunity-design of pharmaceuticals for environmental biodegradability
Kümmerer, K., 06.2019, In: Sustainable Chemistry and Pharmacy. 12, 4 p., 100136.Research output: Journal contributions › Scientific review articles › Research
- Published
GREENER Pharmaceuticals for More Sustainable Healthcare
Moermond, C. T. A., Puhlmann, N., Brown, A. R., Owen, S. F., Ryan, J., Snape, J., Venhuis, B. J. & Kümmerer, K., 13.09.2022, In: Environmental Science and Technology Letters. 9, 9, p. 699-705 7 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Lipids in preventive dentistry
Kensche, A., Reich, M., Kümmerer, K., Hannig, M. & Hannig, C., 04.2013, In: Clinical Oral Investigations. 17, 3, p. 669-685 17 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Material circularity and the role of the chemical sciences as a key enabler of a sustainable post-trash age
Matlin, S. A., Mehta, G., Hopf, H., Krief, A., Keßler, L. & Kümmerer, K., 01.09.2020, In: Sustainable Chemistry and Pharmacy. 17, 11 p., 100312.Research output: Journal contributions › Scientific review articles › Research
- Published
Modeling and predicting aquatic aerobic biodegradation: a review from a user’s perspective.
Rücker, C. & Kümmerer, K., 04.2012, In: Green Chemistry . 14, 4, p. 875-887 13 p.Research output: Journal contributions › Scientific review articles › Research