Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Published
Water quantity and quality dynamics of the THC - Tuyamuyun hydroengineering complex - and implications for reservoir operation
Froebrich, J., Bauer, M., Ikramova, M. & Olsson, O., 09.2007, In: Environmental Science and Pollution Research. 14, 6, p. 435-442 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Reliving the past in a changed environment: Hydropower ambitions, opportunities and constraints in Tajikistan
Wegerich, K., Olsson, O. & Froebrich, J., 01.07.2007, In: Energy Policy. 35, 7, p. 3815-3825 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Jayhun - Grenzüberschreitendes Wasserressourcenmanagement des Amu Darya für eine nachhaltige Zukunft im Aralseebecken
Olsson, O., 08.2009, In: Hydrologie und Wasserbewirtschaftung. 53, 4, p. 271-272 2 p.Research output: Journal contributions › Journal articles › Research
- Published
Applicability of adapted reservoir operation for water stress mitigation under dry year conditions
Olsson, O., Ikramova, M., Bauer, M. & Froebrich, J., 01.2010, In: Water Resources Management. 24, 2, p. 277-297 21 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Late developers and the inequity of "equitable utilization" and the harm of "do no harm"
Wegerich, K. & Olsson, O., 11.2010, In: Water International. 35, 6, p. 707-717 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Synthesis of Room-Temperature Ionic Liquids with the Weakly Coordinating [Al(ORF)(4)](-) Anion (R-F = C(H)(CF3)(2)) and the Determination of Their Principal Physical Properties
Bulut, S., Klose, P., Huang, M-M., Weingartner, H., Dyson, P. J., Laurenczy, G., Friedrich, C., Menz, J., Kummerer, K. & Krossing, I., 22.11.2010, In: Chemistry - A European Journal. 16, 44, p. 13139-13154 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Neuartige Spurenstoffe im Wasser
Kümmerer, K., 12.2010, In: Hydrologie und Wasserbewirtschaftung. 54, 6, p. 349-359 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Chemische Stoffe in der Umwelt
Kümmerer, K. & Ruck, W., 2014, Nachhaltigkeitswissenschaften. Heinrichs, H. & Michelsen, G. (eds.). Berlin, Heidelberg: Springer Spektrum, p. 175-211 27 p.Research output: Contributions to collected editions/works › Contributions to collected editions/anthologies › Education › peer-review
- Published
Photodegradation, Photocatalytic and Aerobic Biodegradation of Sulfisomidine and Identification of Transformation Products By LC–UV-MS/MS
Sleman, F., Mahmoud, W. M. M., Schubert, R. & Kümmerer, K., 11.2012, In: Clean - Soil, Air, Water. 40, 11, p. 1244-1249 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The use of a monolithic column to improve the simultaneous determination of caffeine, paracetamol, pseudoephedrine, aspirin, dextromethorphan, chlorpheniramine in pharmaceutical formulations by HPLC-A comparison with a conventional reversed-phase silica-based column
Hadad, G. M. & Mahmoud, W. M. M., 01.12.2011, In: Journal of Liquid Chromatography and Related Technologies. 34, 20, p. 2516–2532 17 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Release of monomers from four different composite materials after halogen and LED curing
Polydorou, O., König, A., Altenburger, M. J., Wolkewitz, M., Hellwig, E. & Kümmerer, K., 01.10.2011, In: American Journal of Dentistry. 24, 5, p. 315-321 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Genotoxic effect of ciprofloxacin during photolytic decomposition monitored by the in vitro micronucleus test (MNvit) in HepG2 cells
Garcia-Käufer, M., Bergheim, M., Gminski, R., Gupta, P., Mathur, N., Kümmerer, K., Mersch-Sundermann, V. & Haddad, T., 06.2012, In: Environmental Science and Pollution Research. 19, 5, p. 1719-1727 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Assessment of pharmaceutical waste management at selected hospitals and homes in Ghana
Sasu, S., Kümmerer, K. & Kranert, M., 06.2012, In: Waste Management & Research. 30, 6, p. 625-630 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes: Degradation, elucidation of byproducts and assessment of their biological potency
Fatta-Kassinos, D., Vasquez, M. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 693-709 17 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Biodegradability and ecotoxicitiy of tramadol, ranitidine, and their photoderivatives in the aquatic environment: Biologische Abbaubarkeit und Ökotoxizität von Tramadol, Ranitidin sowie ihren Photoderivate in der aquatischen Umwelt
Bergheim, M., Gieré, R. & Kümmerer, K., 01.2012, In: Environmental Science and Pollution Research. 19, 1, p. 72-85 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
Trautwein, C. & Kümmerer, K., 10.2011, In: Chemosphere. 85, 5, p. 765-773 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols
Lundberg, K., Roos, A-K., Pavlenko, M., Leder, C., Wehrum, D., Guevara-Patiño, J., Andersen, R. S. & Pisa, P., 04.03.2009, In: Vaccine. 27, 10, p. 1557-1565 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Development and validation of a stability-indicating RP-HPLC method for the determination of paracetamol with dantrolene or/and cetirizine and pseudoephedrine in two pharmaceutical dosage forms
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 15.10.2009, In: Talanta. 79, 5, p. 1360-1367 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biomonitoring Hospital Effluents by the Allium cepa L. Test
Bagatini, M. D., Vasconcelos, T. G., Laughinghouse IV, H. D. & Martins, A. F., 05.2009, In: Bulletin of Environmental Contamination and Toxicology. 82, 5, p. 590-592 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inhibition of foam cell formation using a soluble CD68-Fc fusion protein
Daub, K., Siegel-Axel, D., Schönberger, T., Leder, C., Seizer, P., Müller, K., Schaller, M., Penz, S., Menzel, D., Buchele, B., Bültmann, A., Münch, G., Lindemann, S., Simmet, T. & Gawaz, M., 09.2010, In: Journal of Molecular Medicine. 88, 9, p. 909-920 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Modulating immune responses and inflammation
Leder, C., Ziegler, M. & Gawaz, M., 03.2010, In: Seminars in Thrombosis and Hemostasis. 36, 2, p. 219-222 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies
Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T. G., Gueutin, C., Guterres, S. S., Pohlmann, A. R. & Fattal, E., 21.08.2011, In: Soft Matter. 7, 16, p. 7304-7312 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine
Hadad, G. M., Emara, S. & Mahmoud, W. M. M., 12.2009, In: Chromatographia. 70, 11/12, p. 1593–1598 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Response to David B. Brooks
Wegerich, K. & Olsson, O., 05.2011, In: Water International. 36, 3, p. 410-413 4 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A Glance at the World
Sasu, S., Metzger, J., Kranert, M. & Kümmerer, K., 11.2011, In: Waste Management. 31, 11, p. 2361-2364 4 p.Research output: Journal contributions › Other (editorial matter etc.) › Research
- Published
The effect of storage medium on the elution of monomers from composite materials
Polydorou, O., Huberty, C., Wolkewitz, M., Bolek, R., Hellwig, E. & Kümmerer, K., 27.01.2012, In: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 100B, 1, p. 68-74 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The Role Of The Amu Darya Dams And Reservoirs In Future Water Supply In The Amu Darya Basin
Olsson, O., Bauer, M., Ikramova, M. & Froebrich, J., 2008, Environmental Problems of Central Asia and their Economic, Social and Security Impacts. Qi, J. & Evered, K. T. (eds.). Dordrecht: Springer, p. 277-292 16 p. (NATO science for peace and security series, Series C: Environmental security).Research output: Contributions to collected editions/works › Contributions to collected editions/anthologies › Research
- Published
Interstate Water Resource Risk Management: Towards a Sustainable Future for the Aral Basin (JAYHUN)
Olsson, O. (ed.) & Bauer, M. (ed.), 2010, London: IWA Publishing. 121 p.Research output: Books and anthologies › Collected editions and anthologies › Research
- Published
Modelling scenarios to identify a combined sediment-water management strategy for the large reservoirs of the Tuyamuyun hydro-complex
Olsson, O., Sorokin, A. & Ikramova, M., 03.2011, In: Irrigation and Drainage Systems. 25, 1, p. 1-18 18 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradability of organic nanoparticles in the aqueous environment
Kümmerer, K., Menz, J., Schubert, T. & Thielemans, W., 03.2011, In: Chemosphere. 82, 10, p. 1387-1392 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Effect of safflower oil on the protective properties of the in situ formed salivary pellicle
Hannig, C., Wagenschwanz, C., Pötschke, S., Kümmerer, K., Kensche, A., Hoth-Hannig, W. & Hannig, M., 08.2012, In: Caries Research. 46, 5, p. 496-506 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Photolysis of sulfamethoxypyridazine in various aqueous media: Aerobic biodegradation and photoproducts identification by LC-UV-MS/MS
Khaleel, N. D. H., Mahmoud, W. M. M., Hadad, G. M., Abdel-Salam, R. A. & Kümmerer, K., 2012, In: Chemicke Listy. 106, S4, p. 904 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Photodegradation of thalidomide: Identification of transformation products by LC-UV-FL-MS/MS, assessment of biodegradability, cytotoxicity and mutagenicity.
Mahmoud, W. M. M., Toolaram, A. P., Schneider, M. & Kümmerer, K., 2012, 4th EuCheMS Chemistry Congress: Abstract book. Association of Czech Chemical Societies, Vol. 106. p. 650 1 p. (Chemické listy; vol. 106, no. S4).Research output: Contributions to collected editions/works › Published abstract in conference proceedings › Research › peer-review
- Published
Photolysis of sulfamethoxypyridazine in various aqueous media: Aerobic biodegradation and identification of photoproducts by LC-UV-MS/MS
Khaleel, N. D. H., Mahmoud, W. M. M., Hadad, G. M., Abdel-Salam, R. A. & Kümmerer, K., 15.01.2013, In: Journal of Hazardous Materials. 244-245, p. 654-661 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Wissen Kompakt: Zur Funktion didaktischer Erklärungsmodelle
Bolek, R. & Landwehr, B., 10.2012, In: Grundschule Sachunterricht. 56, p. 6-7 2 p.Research output: Journal contributions › Journal articles › Transfer › peer-review
- Published
Wissen Kompakt: Kunststoffe und ihre Entstehung
Bolek, R., 10.2012, In: Grundschule Sachunterricht. 56, p. 4-5 2 p.Research output: Journal contributions › Journal articles › Transfer › peer-review
- Published
Lipids in preventive dentistry
Kensche, A., Reich, M., Kümmerer, K., Hannig, M. & Hannig, C., 04.2013, In: Clinical Oral Investigations. 17, 3, p. 669-685 17 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Biodegradation potential of ofloxacin and its resulting transformation products during photolytic and photocatalytic treatment
Vasquez, M., Hapeshi, E., Fatta-Kassinos, D. & Kümmerer, K., 03.2013, In: Environmental Science and Pollution Research. 20, 3, p. 1302-1309 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
aCD133-GPVI: A bifunctional protein for imroved stent performance and endothelial regeneration
Baumer, Y., Leder, C., Schönberger, T., Ziegler, M., Filzmayer, C., Bühring, H-J. & Gawaz, M., 2011, In: Tissue Engineering Part A. 17, 3/4, p. 554 1 p.Research output: Journal contributions › Conference abstract in journal › Research
- Published
Multivariate Optimization of Analytical Methodology and a First Attempt to an Environmental Risk Assessment of β-Blockers in Hospital Wastewater
Wilde, M. L., Kümmerer, K. & Martins, A. F., 25.09.2012, In: Journal of the Brazilian Chemical Society. 23, 9, p. 1732-1740 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Das Fettsäureprofil des initialen oralen Biofilms (Pellikel) - eine In-situ-Studie
Reich, M., Hannig, C., Al-Ahmad, A. & Kümmerer, K., 04.2012, In: Deutsche Zahnärztliche Zeitschrift. 67, 4, p. D18 1 p.Research output: Journal contributions › Conference abstract in journal › Research › peer-review
- Published
Modification of the umu-assay (ISO 13829) accounting for cytotoxicity in genotoxicity assessment: A preliminary study
Toolaram, A. P., Gutiérrez, I. R. & Ahlf, W., 18.09.2012, In: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 747, 2, p. 190-196 7 p.Research output: Journal contributions › Journal articles › Research
- Published
Basin efficiency approach and its effect on streamflow quality, Zerafshan River Uzbekistan
Olsson, O., Gassmann, M., Manig, N., Ikramova, M. & Wegerich, K., 07.01.2013, In: Journal of Hydrology. 476, 7, p. 128–135 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Fate of Pesticides and Their Transformation Products: First Flush Effects in a Semi-Arid Catchment
Olsson, O., Khodorkovsky, M., Gassmann, M., Friedler, E., Schneider, M. & Dubowski, Y., 02.2013, In: Clean - Soil, Air, Water. 41, 2, p. 134-142 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Hydraulic Fracturing: Zusammensetzung und Entsorgung anfallender Abwässer
Olsson, O., Weichgrebe, D. & Rosenwinkel, K-H., 09.2012, In: Wasser und Abfall. 14, 9, p. 10-15 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A comprehensive method for determination of fatty acids in the initial oral biofilm (pellicle)
Reich, M., Hannig, C., Al-Ahmad, A., Bolek, R. & Kuemmerer, K., 01.10.2012, In: Journal of Lipid Research. 53, 10, p. 2226-2230 5 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Random peptide library displayed on AAV vectors targeting human primary coronary artery endothelial cells
Kleinschmidt, J., Müller, O., Trepel, M., Kaul, F. & Leder, C., 30.09.2004, IPC No. C12N 15/10 (2006.01), PCT/EP2004/002923 , WIPO - Weltorganisation für geistiges Eigentum, Patent No. WO 2004083441, 19.03.2004, Priority date 19.03.2003Research output: Patents › Patent
- Published
Methods and compositions relating to a vaccine against prostate cancer
Leder, C., King, A. D., Pavlenko, M. & Pisa, P., 04.01.2007, IPC No. A61K39/00 (2006.01), Patent No. WO/2007/002149 A2, 21.06.2006Research output: Patents › Patent
- Published
Fusionsprotein und dessen Verwendungen
Leder, C., Gawaz, M., Ziegler, M. & Stellos, K., 06.10.2011, IPC No. DE 102010013887A1, Deutsches Patent- und Markenamt, 30.03.2010Research output: Patents › Patent
- Published
Gremlin fusion products with immunoglobulin Fc domains and their use as antiinflammatories or immunomodulators
Gawaz, M., Müller, I., Leder, C. & Filzmayer, C., 24.05.2012, IPC No. DE 102010052941A1, Deutsches Patent- und Markenamt, 18.11.2010, Priority date 24.05.2012Research output: Patents › Patent