Is a severe clinical profile an effect modifier in a web-based depression treatment for adults with type 1 or type 2 diabetes ? Secondary analyses from a randomized controlled trial
Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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in: Journal of Medical Internet Research, Jahrgang 14, Nr. 1, e2, 05.01.2012.
Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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TY - JOUR
T1 - Is a severe clinical profile an effect modifier in a web-based depression treatment for adults with type 1 or type 2 diabetes ?
T2 - Secondary analyses from a randomized controlled trial
AU - Van Bastelaar, K.M.P.
AU - Pouwer, F.
AU - Cuijpers, P.
AU - Riper, H.
AU - Twisk, J.W.R.
AU - Snoek, F.J.
N1 - Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/1/5
Y1 - 2012/1/5
N2 - Background: Depression and diabetes are two highly prevalent and co-occurring health problems. Web-based, diabetes-specific cognitive behavioral therapy (CBT) depression treatment is effective in diabetes patients, and has the potential to be cost effective and to have large reach. A remaining question is whether the effectiveness differs between patients with seriously impaired mental health and patients with less severe mental health problems. Objective: To test whether the effectiveness of an eight-lesson Web-based, diabetes-specific CBT for depression, with minimal therapist support, differs in patients with or without diagnosed major depressive disorder (MDD), diagnosed anxiety disorder, or elevated diabetes-specific emotional distress (DM-distress). Methods: We used data of 255 patients with diabetes with elevated depression scores, who were recruited via an open access website for participation in a randomized controlled trial, conducted in 2008-2009, comparing a diabetes-specific, Web-based, therapist-supported CBT with a 12-week waiting-list control group. We performed secondary analyses on these data to study whether MDD or anxiety disorder (measured using a telephone-administered diagnostic interview) and elevated DM-distress (online self-reported) are effect modifiers in the treatment of depressive symptoms (online self-reported) with Web-based diabetes-specific CBT. Results: MDD, anxiety disorder, and elevated DM-distress were not significant effect modifiers in the treatment of self-assessed depressive symptoms with Web-based diabetes-specific CBT. Conclusions: This Web-based diabetes-specific CBT depression treatment is suitable for use in patients with severe mental health problems and those with a less severe clinical profile.
AB - Background: Depression and diabetes are two highly prevalent and co-occurring health problems. Web-based, diabetes-specific cognitive behavioral therapy (CBT) depression treatment is effective in diabetes patients, and has the potential to be cost effective and to have large reach. A remaining question is whether the effectiveness differs between patients with seriously impaired mental health and patients with less severe mental health problems. Objective: To test whether the effectiveness of an eight-lesson Web-based, diabetes-specific CBT for depression, with minimal therapist support, differs in patients with or without diagnosed major depressive disorder (MDD), diagnosed anxiety disorder, or elevated diabetes-specific emotional distress (DM-distress). Methods: We used data of 255 patients with diabetes with elevated depression scores, who were recruited via an open access website for participation in a randomized controlled trial, conducted in 2008-2009, comparing a diabetes-specific, Web-based, therapist-supported CBT with a 12-week waiting-list control group. We performed secondary analyses on these data to study whether MDD or anxiety disorder (measured using a telephone-administered diagnostic interview) and elevated DM-distress (online self-reported) are effect modifiers in the treatment of depressive symptoms (online self-reported) with Web-based diabetes-specific CBT. Results: MDD, anxiety disorder, and elevated DM-distress were not significant effect modifiers in the treatment of self-assessed depressive symptoms with Web-based diabetes-specific CBT. Conclusions: This Web-based diabetes-specific CBT depression treatment is suitable for use in patients with severe mental health problems and those with a less severe clinical profile.
KW - Health sciences
KW - Adults
KW - Behavior therapy
KW - Cognitive therapy
KW - Depression
KW - Depressive disorder
KW - Diabetes mellitus type 1
KW - Diabetes mellitus type 2
KW - Psychology
KW - Psychology
UR - http://www.scopus.com/inward/record.url?scp=84856238978&partnerID=8YFLogxK
U2 - 10.2196/jmir.1657
DO - 10.2196/jmir.1657
M3 - Journal articles
C2 - 22262728
AN - SCOPUS:84856238978
VL - 14
JO - Journal of Medical Internet Research
JF - Journal of Medical Internet Research
SN - 1438-8871
IS - 1
M1 - e2
ER -