Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Standard

Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial. / Schaub, Michael P.; Blankers, Matthijs; Lehr, Dirk et al.
in: BMJ Open, Jahrgang 6, Nr. 5, e011457, 01.05.2016.

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

Harvard

APA

Schaub, M. P., Blankers, M., Lehr, D., Boss, L., Riper, H., Dekker, J., Goudriaan, A. E., Maier, L. J., Haug, S., Amann, M., Dey, M., Wenger, A., & Ebert, D. D. (2016). Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial. BMJ Open, 6(5), Artikel e011457. https://doi.org/10.1136/bmjopen-2016-011457

Vancouver

Bibtex

@article{b46a5db023c04338a9822a3dde5e55a5,
title = "Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: Study protocol of a three-arm randomised controlled trial",
abstract = "Introduction: In the general population, alcohol use disorder and depression more often occur together than any other combination of a mental illness with a substance use disorder. It is important to have a cost-effective intervention that is able to reach at-risk individuals in the early stages of developing alcohol use disorders and depression disorders. Methods and analysis: This paper presents the protocol for a 3-arm multicentre randomised controlled trial (RCT) to test the efficacy and cost-effectiveness of the combined internet-based self-help intervention Take Care of You (TCOY) to reduce alcohol misuse and depression symptoms in comparison with a waiting list control group and a comparable intervention focusing on problematic alcohol use only. The active interventions consist of modules designed to reduce alcohol use, based on the principles of motivational interviewing and methods of cognitive behavioural therapy, together with additional modules in the combined study arm to reduce symptoms of depression. Data will be collected at baseline, as well as at 3 and 6 months postrandomisation. The primary outcome is the quantity of alcohol used in the past 7 days. A number of secondary outcome measures will be studied. These include the Centre of Epidemiologic Studies of Depression Scale (CES-D) and a combined measure with the criteria of values below the cut-off for severe alcohol use disorder and for CES-D. Data analysis will follow the intention-to-treat principle using (generalised) linear mixed models. In order to investigate the interventions' cost-utility and cost-effectiveness, a full economic evaluation will be performed. Ethics and dissemination: This RCT will be executed in compliance with the Helsinki Declaration and has been approved by 2 local Ethics Committees. Results will be reported at conferences and in peer-reviewed publications. Participant-friendly summaries of trial findings will be published on the TCOY websites. Trial registration number: ISRCTN10323951.",
keywords = "Health sciences, Psychology",
author = "Schaub, {Michael P.} and Matthijs Blankers and Dirk Lehr and Leif Boss and Heleen Riper and Jack Dekker and Goudriaan, {Anna E.} and Maier, {Larissa J.} and Severin Haug and Manuel Amann and Michelle Dey and Andreas Wenger and Ebert, {David D.}",
year = "2016",
month = may,
day = "1",
doi = "10.1136/bmjopen-2016-011457",
language = "English",
volume = "6",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "BMJ Publishing Group",
number = "5",

}

RIS

TY - JOUR

T1 - Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults

T2 - Study protocol of a three-arm randomised controlled trial

AU - Schaub, Michael P.

AU - Blankers, Matthijs

AU - Lehr, Dirk

AU - Boss, Leif

AU - Riper, Heleen

AU - Dekker, Jack

AU - Goudriaan, Anna E.

AU - Maier, Larissa J.

AU - Haug, Severin

AU - Amann, Manuel

AU - Dey, Michelle

AU - Wenger, Andreas

AU - Ebert, David D.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Introduction: In the general population, alcohol use disorder and depression more often occur together than any other combination of a mental illness with a substance use disorder. It is important to have a cost-effective intervention that is able to reach at-risk individuals in the early stages of developing alcohol use disorders and depression disorders. Methods and analysis: This paper presents the protocol for a 3-arm multicentre randomised controlled trial (RCT) to test the efficacy and cost-effectiveness of the combined internet-based self-help intervention Take Care of You (TCOY) to reduce alcohol misuse and depression symptoms in comparison with a waiting list control group and a comparable intervention focusing on problematic alcohol use only. The active interventions consist of modules designed to reduce alcohol use, based on the principles of motivational interviewing and methods of cognitive behavioural therapy, together with additional modules in the combined study arm to reduce symptoms of depression. Data will be collected at baseline, as well as at 3 and 6 months postrandomisation. The primary outcome is the quantity of alcohol used in the past 7 days. A number of secondary outcome measures will be studied. These include the Centre of Epidemiologic Studies of Depression Scale (CES-D) and a combined measure with the criteria of values below the cut-off for severe alcohol use disorder and for CES-D. Data analysis will follow the intention-to-treat principle using (generalised) linear mixed models. In order to investigate the interventions' cost-utility and cost-effectiveness, a full economic evaluation will be performed. Ethics and dissemination: This RCT will be executed in compliance with the Helsinki Declaration and has been approved by 2 local Ethics Committees. Results will be reported at conferences and in peer-reviewed publications. Participant-friendly summaries of trial findings will be published on the TCOY websites. Trial registration number: ISRCTN10323951.

AB - Introduction: In the general population, alcohol use disorder and depression more often occur together than any other combination of a mental illness with a substance use disorder. It is important to have a cost-effective intervention that is able to reach at-risk individuals in the early stages of developing alcohol use disorders and depression disorders. Methods and analysis: This paper presents the protocol for a 3-arm multicentre randomised controlled trial (RCT) to test the efficacy and cost-effectiveness of the combined internet-based self-help intervention Take Care of You (TCOY) to reduce alcohol misuse and depression symptoms in comparison with a waiting list control group and a comparable intervention focusing on problematic alcohol use only. The active interventions consist of modules designed to reduce alcohol use, based on the principles of motivational interviewing and methods of cognitive behavioural therapy, together with additional modules in the combined study arm to reduce symptoms of depression. Data will be collected at baseline, as well as at 3 and 6 months postrandomisation. The primary outcome is the quantity of alcohol used in the past 7 days. A number of secondary outcome measures will be studied. These include the Centre of Epidemiologic Studies of Depression Scale (CES-D) and a combined measure with the criteria of values below the cut-off for severe alcohol use disorder and for CES-D. Data analysis will follow the intention-to-treat principle using (generalised) linear mixed models. In order to investigate the interventions' cost-utility and cost-effectiveness, a full economic evaluation will be performed. Ethics and dissemination: This RCT will be executed in compliance with the Helsinki Declaration and has been approved by 2 local Ethics Committees. Results will be reported at conferences and in peer-reviewed publications. Participant-friendly summaries of trial findings will be published on the TCOY websites. Trial registration number: ISRCTN10323951.

KW - Health sciences

KW - Psychology

UR - http://www.scopus.com/inward/record.url?scp=84971300453&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2016-011457

DO - 10.1136/bmjopen-2016-011457

M3 - Journal articles

C2 - 27225652

AN - SCOPUS:84971300453

VL - 6

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 5

M1 - e011457

ER -

Dokumente

DOI

Zuletzt angesehen

Publikationen

  1. Exports, foreign direct investment, and productivity
  2. Impact of an acceptance facilitating intervention on diabetes patients' acceptance of Internet-based interventions for depression
  3. Drawing blanks and winning
  4. The Influence Of Product Reuse On Production Planning and Control
  5. Multifractality of overlapping non-uniform self-similar measures
  6. Grain refinement of Mg-Al alloys by carbon inoculation
  7. Learning the hard way
  8. On the Problems of Honorary Work in German Sports Clubs – A Qualitative-Dominated Crossover Mixed Methods Study
  9. Development of recyclable Mg-based alloys
  10. Creep and hot working behavior of a new magnesium alloy Mg-3Sn-2Ca
  11. Meta-analytic cointegrating rank tests for dependent panels
  12. Measurement approaches for inigrated reporting adoption and quality
  13. Ablauforganisation in Arztpraxen
  14. Investigations on microstructure and properties of Mg-Sn-Ca alloys with 3% Al additions
  15. Evaluating a web-based PPGIS for the rehabilitation of urban riparian corridors
  16. Multiscale performance of landscape metrics as indicators of species richness of plants, insects and vertebrates
  17. Mechanical behaviors of extruded Mg alloys with high Gd and Nd content
  18. Policy schemes, operational strategies and system integration of residential co-generation fuel cells.
  19. Is there an excess of significant findings in published studies of psychotherapy for depression?
  20. Organic farming affects the biological control of hemipteran pests and yields in spring barley independent of landscape complexity
  21. Assessing Trust by Disclosure in Online Social Networks
  22. Product diversification and stability of employment and sales
  23. Dynamische Modellierung der Sorption von Substanzen in einem hydrologischen Einzugsgebietsmodell anhand des Beispiels Phosphor
  24. Macroeconomic shocks and banks’ foreign assets
  25. Improving compliance with COVID-19 guidance
  26. Predicting expatriate job performance
  27. Alcohol intake can reduce gambling behavior
  28. Statistical Learning and Inference Is Impaired in the Nonclinical Continuum of Psychosis
  29. Schulbezogenes mathematisches Vorwissen von Bewerber*innen auf ein Mathematik-Lehramtsstudium
  30. Plastics in our ocean as transdisciplinary challenge
  31. Investigation On The Influence Of Remanufacturing On Production Planning And Control – A Systematic Literature Review
  32. Stock price reactions to climate science information from the Intergovernmental Panel on Climate Change
  33. Effects of elevated atmospheric CO2 concentrations on barley, sugar beet and wheat in a rotation
  34. Toward “hardened” accountability?
  35. New evidence for vegetation development and timing of Upper Middle Pleistocene interglacials in Northern Germany and tentative correlations
  36. Intermetallic phase characteristics in the Mg–Nd–Zn system
  37. Does Internet-based guided self-help for depression cause harm?
  38. Print exposure across the reading life span
  39. Reaching for the (Product) Stars
  40. Influence of cerium on stress corrosion cracking in AZ91D
  41. Elution of Monomers from Two Conventional Dental Composite Materials
  42. Effects of introspective vs. extraspective instruction in scaling of hedonic properties of flavouring ingredients by Chinese and German subjects
  43. Simulation of the quench sensitivity of the aluminum alloy 6082
  44. Generalising IRT to Discriminate Between Examinees
  45. Systematic study of the effect of non-uniform seal stiffness on the contact stress in flat-faced soft-seated spring operated pressure relief valves
  46. Accurate welding line prediction in extrusion processes