Utilizing Synchrotron Radiation for the Characterization of Biodegradable Magnesium Alloys — From Alloy Development to the Application as Implant Material

Research output: Journal contributionsScientific review articlesResearch

Authors

  • Berit Zeller-Plumhoff
  • Domonkos Tolnai
  • Martin Wolff
  • Imke Greving
  • Norbert Hort
  • Regine Willumeit-Römer

Magnesium alloys are highly attractive for their application as structural materials as well as medical implants. A range of alloying systems exists which are investigated, e.g., in terms of alloy microstructure changes, in particular during different processing steps or mechanical testing, and in terms of the associated corrosion performance of the material. Synchrotron radiation and in particular synchrotron radiation microcomputed tomography and nanotomography yield a unique opportunity to investigate such changes and processes in 3D at high resolution and in situ, thus significantly broadening our knowledge base. Herein, the benefits of using synchrotron radiation for the investigation of magnesium alloys with particular respect to its application as a biodegradable implant are demonstrated. Advances in experimental environments for in situ testing are reviewed, and all stages of materials testing are covered in which synchrotron radiation has been used, i.e., from developing and processing of the material, to corrosion testing and assessing implant integration and stability ex vivo. This review incorporates advances both in micro- and nanotomographic imaging regimes and further includes complementary techniques, such as X-ray diffraction, small angle X-ray scattering, X-ray fluorescence, and diffraction tomography. Finally, an outlook into future developments is provided.

Original languageEnglish
Article number2100197
JournalAdvanced Engineering Materials
Volume23
Issue number11
Number of pages16
ISSN1438-1656
DOIs
Publication statusPublished - 11.2021

Bibliographical note

The authors thank Dr. Björn Wiese for providing the CAD rendering of the screw used in the graphical abstract. This project has received funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 811226. The authors acknowledge funding by the Röntgen-Ångström Cluster (RÅC), a bilateral research collaboration of the Swedish government and the German Federal Ministry of Education and Research (BMBF project number 05K16CGA), and BMBF-funded project MgBone (05K16CGB). I.G. gratefully acknowledges the financial support from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project number 192346071, SFB 986 (project Z2). Open access funding enabled and organized by Projekt DEAL.

Publisher Copyright:
© 2021 The Authors. Advanced Engineering Materials published by Wiley-VCH GmbH.

    Research areas

  • biodegradable magnesium implants, in situ testing, magnesium alloys, synchrotron radiation
  • Engineering

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