Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Journal articles › Research › Not peer-reviewed
- Published
Wie teuer wird die Medizin im Wasser?
Kümmerer, K., 01.2018, In: Zweitausend50. 1, p. 70-73 4 p.Research output: Journal contributions › Journal articles › Research
- Journal articles › Research › Peer-reviewed
- Published
Abiotic and biotic degradation of five aromatic organosilicon compounds in aqueous media: Structure degradability relationships
Grabitz, E., Olsson, O., Amsel, A-K., Rummel, B., Mitzel, N. W. & Kümmerer, K., 15.06.2020, In: Journal of Hazardous Materials. 392, 15 p., 122429.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Acknowledging temporal diversity in sustainability transformations at the nexus of interconnected systems
Weiser, A., Lutz, L. M., Lang, D. J. & Kümmerer, K., 20.09.2017, In: Journal of Cleaner Production. 162, p. 273-285 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A comparative assessment of the transformation products of S-metolachlor and its commercial product Mercantor Gold® and their fate in the aquatic environment by employing a combination of experimental and in silico methods
Gutowski, L., Olsson, O., Leder, C. & Kümmerer, K., 15.02.2015, In: The Science of The Total Environment. 506-507, p. 369-379 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A comprehensive method for determination of fatty acids in the initial oral biofilm (pellicle)
Reich, M., Hannig, C., Al-Ahmad, A., Bolek, R. & Kuemmerer, K., 01.10.2012, In: Journal of Lipid Research. 53, 10, p. 2226-2230 5 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans
Scholtka, B., Schneider, M., Melcher, R., Katzenberger, T., Friedrich, D., Berghof-Jäger, K., Scheppach, W. & Steinberg, P., 08.2009, In: Cancer Epidemiology. 33, 2, p. 123-129 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A kinetic study of the photolysis of sulfamethoxazole with special emphasis on the photoisomer
Palm, W. U., Schmidt, N., Stahn, M. & Grimme, S., 01.03.2023, In: Photochemical and Photobiological Sciences. 22, 3, p. 615-630 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols
Lundberg, K., Roos, A-K., Pavlenko, M., Leder, C., Wehrum, D., Guevara-Patiño, J., Andersen, R. S. & Pisa, P., 04.03.2009, In: Vaccine. 27, 10, p. 1557-1565 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antibiotic residues in livestock manure: Does the EU risk assessment sufficiently protect against microbial toxicity and selection of resistant bacteria in the environment?
Menz, J., Olsson, O. & Kümmerer, K., 05.11.2019, In: Journal of Hazardous Materials. 379, 120807.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antibiotics and sweeteners in the aquatic environment: biodegradability, formation of phototransformation products, and in vitro toxicity
Bergheim, M., Gminski, R., Spangenberg, B., Debiak, M., Bürkle, A., Mersch-Sundermann, V., Kümmerer, K. & Gieré, R., 01.11.2015, In: Environmental Science and Pollution Research. 22, 22, p. 18017-18030 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antimicrobial activity of pharmaceutical cocktails in sewage treatment plant effluent: An experimental and predictive approach to mixture risk assessment
Menz, J., Baginska, E., Arrhenius, Å., Haiß, A., Backhaus, T. & Kümmerer, K., 01.12.2017, In: Environmental Pollution. 231, 2, p. 1507-1517 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Antineoplastic compounds in the environment: Substances of special concern
Kümmerer, K., Haiß, A., Schuster, A., Hein, A. & Ebert, I., 01.08.2016, In: Environmental Science and Pollution Research. 23, 15, p. 14791–14804 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Applicability of adapted reservoir operation for water stress mitigation under dry year conditions
Olsson, O., Ikramova, M., Bauer, M. & Froebrich, J., 01.2010, In: Water Resources Management. 24, 2, p. 277-297 21 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Approach for detecting mutagenicity of biodegraded and ozonated pharmaceuticals, metabolites and transformation products from a drinking water perspective
Gartiser, S., Hafner, C., Kronenberger-Schäfer, K., Happel, O., Trautwein, C. & Kümmerer, K., 09.2012, In: Environmental Science and Pollution Research. 19, 8, p. 3597-3609 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Aquatic photochemistry, abiotic and aerobic biodegradability of thalidomide: Identification of stable transformation products by LC-UV-MS(n.)
Mahmoud, W. M. M., Trautwein, C., Leder, C. & Kümmerer, K., 01.10.2013, In: The Science of The Total Environment. 463-464, p. 140-150 11 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Are Si-C bonds cleaved by microorganisms? A critical review on biodegradation of methylsiloxanes
Rücker, C., Grabitz, E. & Kümmerer, K., 01.04.2023, In: Chemosphere. 321, 137858.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Are Si–C bonds formed in the environment and/or in technical microbiological systems?
Rücker, C., Winkelmann, M. & Kümmerer, K., 08.2023, In: Environmental Science and Pollution Research. 30, 39, p. 91492-91500 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A scale-up procedure to dialkyl carbonates; evaluation of their properties, biodegradability, and toxicity
Trapasso, G., Salaris, C., Reich, M., Logunova, E., Salata, C., Kümmerer, K., Figoli, A. & Aricò, F., 01.05.2022, In: Sustainable Chemistry and Pharmacy. 26, 100639.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Assessing the environmental fate of S-metolachlor, its commercial product Mercantor Gold® and their photoproducts using a water-sediment test and in silico methods
Gutowski, L., Baginska, E., Olsson, O., Leder, C. & Kümmerer, K., 01.11.2015, In: Chemosphere. 138, p. 847-855 9 p., 16405.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Assessment of pharmaceutical waste management at selected hospitals and homes in Ghana
Sasu, S., Kümmerer, K. & Kranert, M., 06.2012, In: Waste Management & Research. 30, 6, p. 625-630 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Assessment of the biotic and abiotic elimination processes of five micropollutants during cultivation of the green microalgae Acutodesmus obliquus
Reymann, T., Kerner, M. & Kümmerer, K., 09.2020, In: Bioresource Technology Reports. 11, 100512.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A strategy for an initial assessment of the ecotoxicological effects of transformation products of pesticides in aquatic systems following a tiered approach
Hensen, B., Olsson, O. & Kümmerer, K., 01.04.2020, In: Environment international. 137, 12 p., 105533.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol
Rastogi, T., Leder, C. & Kummerer, K., 2015, In: RSC Advances. 5, 1, p. 27-32 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
B7-H1 Selectively Controls TH17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway
Herold, M., Posevitz, V., Chudyka, D., Hucke, S., Groß, C., Kurth, F., Leder, C., Loser, K., Kurts, C., Knolle, P., Klotz, L. & Wiendl, H., 15.10.2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 8, p. 3584-3595 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Basin efficiency approach and its effect on streamflow quality, Zerafshan River Uzbekistan
Olsson, O., Gassmann, M., Manig, N., Ikramova, M. & Wegerich, K., 07.01.2013, In: Journal of Hydrology. 476, 7, p. 128–135 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Bioavailability of Antibiotics at Soil-Water Interfaces: A Comparison of Measured Activities and Equilibrium Partitioning Estimates
Menz, J., Müller, J., Olsson, O. & Kümmerer, K., 05.06.2018, In: Environmental Science & Technology. 52, 11, p. 6555-6564 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradability and ecotoxicitiy of tramadol, ranitidine, and their photoderivatives in the aquatic environment: Biologische Abbaubarkeit und Ökotoxizität von Tramadol, Ranitidin sowie ihren Photoderivate in der aquatischen Umwelt
Bergheim, M., Gieré, R. & Kümmerer, K., 01.2012, In: Environmental Science and Pollution Research. 19, 1, p. 72-85 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradability of organic nanoparticles in the aqueous environment
Kümmerer, K., Menz, J., Schubert, T. & Thielemans, W., 03.2011, In: Chemosphere. 82, 10, p. 1387-1392 6 p.Research output: Journal contributions › Journal articles › Research › peer-review
- E-pub ahead of print
Biodegradation of Flavonoids – Influences of structural features
Schnarr, L., Olsson, O. & Kümmerer, K., 01.07.2024, In: Chemosphere. 359, 11 p., 142234.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradation of the Antituberculosis Drug Isoniazid in the Aquatic Environment
Sasu, S., Metzger, J., Kranert, M. & Kümmerer, K., 01.02.2015, In: Clean - Soil, Air, Water. 43, 2, p. 166-172 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradation potential of ofloxacin and its resulting transformation products during photolytic and photocatalytic treatment
Vasquez, M., Hapeshi, E., Fatta-Kassinos, D. & Kümmerer, K., 03.2013, In: Environmental Science and Pollution Research. 20, 3, p. 1302-1309 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradation screening of chemicals in an artificial matrix simulating the water-sediment interface
Baginska, E., Haiß, A. & Kümmerer, K., 01.01.2015, In: Chemosphere. 119, p. 1240-1246 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biodegradation tests of mercaptocarboxylic acids, their esters, related divalent sulfur compounds and mercaptans
Rücker, C., Mahmoud, W. M. M., Schwartz, D. & Kümmerer, K., 01.07.2018, In: Environmental Science and Pollution Research. 25, 19, p. 18393-18411 19 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biomass derived ionic liquids: synthesis from natural organic acids, characterization, toxicity, biodegradation and use as solvents for catalytic hydrogenation processes
Ferlin, N., Courty, M., Gatard, S., Spulak, M., Quilty, B., Beadham, I. G., Ghavre, M., Haiß, A., Kümmerer, K., Gathergood, N. & Bouquillon, S., 29.07.2013, In: Tetrahedron. 69, 30, p. 6150 - 6161 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Biomonitoring Hospital Effluents by the Allium cepa L. Test
Bagatini, M. D., Vasconcelos, T. G., Laughinghouse IV, H. D. & Martins, A. F., 05.2009, In: Bulletin of Environmental Contamination and Toxicology. 82, 5, p. 590-592 3 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Blue-green light is required for a maximized fatty acid unsaturation and pigment concentration in the microalga Acutodesmus obliquus
Helamieh, M., Reich, M., Bory, S., Rohne, P., Riebesell, U., Kerner, M. & Kümmerer, K., 01.07.2022, In: Lipids. 57, 4-5, p. 221-232 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Captopril and its dimer captopril disulfide: Photodegradation, aerobic biodegradation and identification of transformation products by HPLC-UV and LC-ion trap-MS(n)
Mahmoud, W. M. M. & Kümmerer, K., 01.08.2012, In: Chemosphere. 88, 10, p. 1170-1177 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Characterization of photo-transformation products of the antibiotic drug Ciprofloxacin with liquid chromatography-tandem mass spectrometry in combination with accurate mass determination using an LTQ-Orbitrap
Haddad, T. & Kümmerer, K., 11.2014, In: Chemosphere. 115, 1, p. 40-46 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Chronic ecotoxic effects to Pseudomonas putida and Vibrio fischeri, and cytostatic and genotoxic effects to the hepatoma cell line (HepG2) of ofloxacin photo(cata)lytically treated solutions
Vasquez, M., Garcia-Käufer, M., Hapeshi, E., Menz, J., Kostarelos, K., Fatta-Kassinos, D. & Kümmerer, K., 15.04.2013, In: The Science of The Total Environment. 450-451, p. 356-365 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Combination of experimental and in silico methods for the assessment of the phototransformation products of the antipsychotic drug/metabolite Mesoridazine
Wilde, M. L., Menz, J., Leder, C. & Kümmerer, K., 15.03.2018, In: The Science of The Total Environment. 618, p. 697-711 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Combining charcoal sediment and molecular markers to infer a Holocene fire history in the Maya Lowlands of Petén, Guatemala
Schüpbach, S., Kirchgeorg, T., Colombaroli, D., Beffa, G., Radaelli, M., Kehrwald, N. & Barbante, C., 01.05.2015, In: Quaternary Science Reviews. 115, p. 123-131 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Comparison of an Electrochemical and Luminescence-Based Oxygen Measuring System for Use in the Biodegradability Testing According to Closed Bottle Test (OECD 301D)
Friedrich, J., Längin, A. & Kümmerer, K., 03.2013, In: Clean - Soil, Air, Water. 41, 3, p. 251-257 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Comparison of PSA-specific CD8+ CTL responses and antitumor immunity generated by plasmid DNA vaccines encoding PSA-HSP chimeric proteins
Pavlenko, M., Roos, A-K., Leder, C., Hansson, L. O., Kiessling, R., Levitskaya, E. & Pisa, P., 12.2004, In: Cancer Immunology, Immunotherapy . 53, 12, p. 1085-1092 8 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Concentrations and sources of methylxanthines in a Northern German river system
Löher, F., Palm, W. U., Schaffer, M. & Olsson, O., 25.06.2021, In: Science of the Total Environment. 775, 145898.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Consumers' perceptions of biocidal products in households
Wieck, S., Olsson, O. & Kümmerer, K., 03.2018, In: International Journal of Hygiene and Environmental Health. 221, 2, p. 260-268 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Degradation of 5-FU by means of advanced (photo)oxidation processes: UV/H2O2, UV/Fe(2+)/H2O2 and UV/TiO2 - Comparison of transformation products, ready biodegradability and toxicity
Lutterbeck, C. A., Wilde, M. L., Baginska, E., Leder, C., Machado, Ê. L. & Kümmerer, K., 15.09.2015, In: The Science of The Total Environment. 527-528, p. 232-245 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Degradation of cyclophosphamide and 5-fluorouracil by UV and simulated sunlight treatments: Assessment of the enhancement of the biodegradability and toxicity
Lutterbeck, C. A., Wilde, M. L., Baginska, E., Leder, C., Machado, Ê. L. & Kümmerer, K., 01.01.2016, In: Environmental Pollution. 208, Part B, p. 467-476 10 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Degradation of the tricyclic antipsychotic drug chlorpromazine under environmental conditions, identification of its main aquatic biotic and abiotic transformation products by LC-MS n and their effects on environmental bacteria
Trautwein, C. & Kümmerer, K., 15.03.2012, In: Journal of Chromatography B. 889-890, p. 24-38 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Designing green derivatives of β-blocker Metoprolol: A tiered approach for green and sustainable pharmacy and chemistry
Rastogi, T., Leder, C. & Kümmerer, K., 01.09.2014, In: Chemosphere. 111, p. 493-499 7 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Designing greener active pharmaceutical ingredients: Insights from pharmaceutical industry into drug discovery and development
Puhlmann, N., Vidaurre, R. & Kümmerer, K., 01.01.2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106614.Research output: Journal contributions › Journal articles › Research › peer-review