Disabled populations are disproportionally affected by the current climate and environmental crises. However, they are hardly included and their knowledge is neglected in processes addressing these challenges. To achieve the UN Agenda 2030, societies should actively engage with the values, experiences and knowledge held by people with disabilities in science and policy contexts. In this paper, we suggest that addressing ‘deep’ leverage points by 1) recognising diverse valuations of and connections to nature by different social groups (i.e. re-connecting to nature), 2) including disabled populations in decision-making and knowledge creation (i.e. re-structuring institutions), and 3) promoting inclusive education and knowledge generation (i.e. re-thinking knowledge production) can facilitate the development of inclusive transformation pathways and foster sustainable human-nature relationships.