TY - JOUR

T1 - Homogenization for a non-local coupling model

AU - Hochmuth, Reinhard

PY - 2008/12

Y1 - 2008/12

N2 - In [P. Deuflhard and R. Hochmuth, On the thermoregulation in the human microvascular system, Proc. Appl. Math. Mech. 3 (2003), pp. 378–379; P. Deuflhard and R. Hochmuth, Multiscale analysis of thermoregulation in the human microsvascular system, Math. Meth. Appl. Sci. 27 (2004), pp. 971–989; R. Hochmuth and P. Deuflhard, Multiscale analysis for the bio-heat transfer equation–the nonisolated case, Math. Models Methods Appl. Sci. 14(11) (2004), pp. 1621–1634], homogenization techniques are applied to derive an anisotropic variant of the bio-heat transfer equation as asymptotic result of boundary value problems providing a microscopic description for microvascular tissue. In view of a future application on treatment planning in hyperthermia, we investigate here the homogenization limit for a coupling model, which takes additionally into account the influence of convective heat transfer in medium-size blood vessels. This leads to second-order elliptic boundary value problems with non-local boundary conditions on parts of the boundary. Moreover, we present asymptotic estimates for first-order correctors.

AB - In [P. Deuflhard and R. Hochmuth, On the thermoregulation in the human microvascular system, Proc. Appl. Math. Mech. 3 (2003), pp. 378–379; P. Deuflhard and R. Hochmuth, Multiscale analysis of thermoregulation in the human microsvascular system, Math. Meth. Appl. Sci. 27 (2004), pp. 971–989; R. Hochmuth and P. Deuflhard, Multiscale analysis for the bio-heat transfer equation–the nonisolated case, Math. Models Methods Appl. Sci. 14(11) (2004), pp. 1621–1634], homogenization techniques are applied to derive an anisotropic variant of the bio-heat transfer equation as asymptotic result of boundary value problems providing a microscopic description for microvascular tissue. In view of a future application on treatment planning in hyperthermia, we investigate here the homogenization limit for a coupling model, which takes additionally into account the influence of convective heat transfer in medium-size blood vessels. This leads to second-order elliptic boundary value problems with non-local boundary conditions on parts of the boundary. Moreover, we present asymptotic estimates for first-order correctors.

KW - Mathematics

KW - homogenization

KW - non-local boundary conditions

KW - Robin boundary

KW - conditions

KW - correctors

KW - heat transfer

KW - bio-heat equation

KW - hyperthermia

UR - http://www.scopus.com/inward/record.url?scp=85064779521&partnerID=8YFLogxK

U2 - 10.1080/00036810802555433

DO - 10.1080/00036810802555433

M3 - Journal articles

VL - 87

SP - 1311

EP - 1323

JO - Applicable Analysis

JF - Applicable Analysis

SN - 0003-6811

IS - 12

ER -