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Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine

Research output: Journal contributions › Journal articles › Research › peer-review

Standard

Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine. / Hadad, Ghada M.; Emara, Samy; Mahmoud, Waleed M. M.
In: Chromatographia, Vol. 70, No. 11/12, 12.2009, p. 1593–1598.

Research output: Journal contributions › Journal articles › Research › peer-review

Harvard

Hadad, GM, Emara, S & Mahmoud, WMM 2009, 'Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine', Chromatographia, vol. 70, no. 11/12, pp. 1593–1598. https://doi.org/10.1365/s10337-009-1365-8

APA

Hadad, G. M., Emara, S., & Mahmoud, W. M. M. (2009). Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine. Chromatographia, 70(11/12), 1593–1598. https://doi.org/10.1365/s10337-009-1365-8

Vancouver

Hadad GM, Emara S, Mahmoud WMM. Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine. Chromatographia. 2009 Dec;70(11/12):1593–1598. doi: 10.1365/s10337-009-1365-8

Bibtex

@article{1a72ac7d011b4f4db399b92271b512fe,
title = "Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine",
abstract = "A simple and reliable liquid chromatographic method has been developed and validated for the determination of cefdinir in human urine and capsule samples. A chromatographic separation was achieved on a C18 column using a mobile phase consisting of potassium dihydrogen phosphate (10 mM, pH 4.5)–acetonitrile (90:10, v/v). Quantitation was achieved with UV detection at 285 nm, based on peak area with linear calibration curve at a concentration range of 0.7–39 µg mL−1. This method was successfully applied for the establishment of an urinary excretion pattern after oral dose.",
keywords = "Chemistry, Column liquid chromatography, Urinary excretion pattern, Cefdinir",
author = "Hadad, {Ghada M.} and Samy Emara and Mahmoud, {Waleed M. M.}",
year = "2009",
month = dec,
doi = "10.1365/s10337-009-1365-8",
language = "English",
volume = "70",
pages = "1593–1598",
journal = "Chromatographia",
issn = "0009-5893",
publisher = "Springer",
number = "11/12",

}

RIS

TY - JOUR

T1 - Optimization and Validation of an LC Method for the Determination of Cefdinir in Dosage Form and Human Urine

AU - Hadad, Ghada M.

AU - Emara, Samy

AU - Mahmoud, Waleed M. M.

PY - 2009/12

Y1 - 2009/12

N2 - A simple and reliable liquid chromatographic method has been developed and validated for the determination of cefdinir in human urine and capsule samples. A chromatographic separation was achieved on a C18 column using a mobile phase consisting of potassium dihydrogen phosphate (10 mM, pH 4.5)–acetonitrile (90:10, v/v). Quantitation was achieved with UV detection at 285 nm, based on peak area with linear calibration curve at a concentration range of 0.7–39 µg mL−1. This method was successfully applied for the establishment of an urinary excretion pattern after oral dose.

AB - A simple and reliable liquid chromatographic method has been developed and validated for the determination of cefdinir in human urine and capsule samples. A chromatographic separation was achieved on a C18 column using a mobile phase consisting of potassium dihydrogen phosphate (10 mM, pH 4.5)–acetonitrile (90:10, v/v). Quantitation was achieved with UV detection at 285 nm, based on peak area with linear calibration curve at a concentration range of 0.7–39 µg mL−1. This method was successfully applied for the establishment of an urinary excretion pattern after oral dose.

KW - Chemistry

KW - Column liquid chromatography

KW - Urinary excretion pattern

KW - Cefdinir

UR - http://www.scopus.com/inward/record.url?scp=72349097752&partnerID=8YFLogxK

U2 - 10.1365/s10337-009-1365-8

DO - 10.1365/s10337-009-1365-8

M3 - Journal articles

VL - 70

SP - 1593

EP - 1598

JO - Chromatographia

JF - Chromatographia

SN - 0009-5893

IS - 11/12

ER -

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Research output: Journal contributions › Journal articles › Research › peer-review

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Research output: Journal contributions › Scientific review articles › Research

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