Disulfiram (Antabus ®) in der Suchtbehandlung
Research output: Journal contributions › Scientific review articles › Research
Authors
Aim: To review studies from 1996 through 2005 on the effectiveness of disulfiram in the treatment of alcohol and other kinds of substance abuse. Method: A systematic literature search using two databases. Results: With the selection criteria, ten studies were identified that used random assignment to groups and intent-to-treat analyses. Compared to a placebo, treatment with disulfiram led to a significant increase in number of days that patients were abstinent from alcohol. Similar results were observed with regard to cocaine use in cocaine-dependent patients. Conclusions: The effectiveness of disulfiram in alcohol-abuse treatment was confirmed in studies of high methodological standards. In addition, disulfiram has a new application in the treatment of cocaine dependence, but for the time being empirical support for it is limited.
| Translated title of the contribution | Using disulfiram (Antabuse®) in substance-abuse treatment |
|---|---|
| Original language | German |
| Journal | Sucht |
| Volume | 53 |
| Issue number | 2 |
| Pages (from-to) | 72-81 |
| Number of pages | 10 |
| ISSN | 0939-5911 |
| DOIs | |
| Publication status | Published - 01.04.2007 |
| Externally published | Yes |
- Sustainability sciences, Management & Economics