Verhalten von Arzneimitteln in der Wasseraufbereitung: Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika
Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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Verhalten von Arzneimitteln in der Wasseraufbereitung : Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika. / Brückner-Nieder, Uta; Frimmel, Fritz H.; Hüttig, Jana et al.
in: Vom Wasser, Jahrgang 100, 2003, S. 155-168.Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet
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TY - JOUR
T1 - Verhalten von Arzneimitteln in der Wasseraufbereitung
T2 - Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika
AU - Brückner-Nieder, Uta
AU - Frimmel, Fritz H.
AU - Hüttig, Jana
AU - Kümmerer, Klaus
N1 - Editors(s):Wasserschemische Gesellschaft, Fachgruppe in der Gesellschaft Deutscher ChemikerProf. Dr. Martin Jekel First published:15 July 2003 Print ISBN:9783527305667 |Online ISBN:9783527600892 |DOI:10.1002/3527600892 Copyright © 2003 Wiley‐VCH Verlag GmbH & Co. KGaA
PY - 2003
Y1 - 2003
N2 - The elimination potential of two classes of pharmaceuticals in water treatment was examined. Substances representative for the fluoroquinolones, ofloxacine and levofloxacine, showed no reduction in concentration during passage through a model sewage plant working with sewage sludge from a municipal waste water treatment plant. Formation of metabolites, also produced by humans, was found only to a minor extent. However, adsorption on activated carbon showed convenient isotherms for water treatment. As expected, results were better with powdered activated carbon compared to granulous F300. Only poor adsorption was found for the technical polymer Lewatit EP63 as sorbent.The cytotoxic substances carboplatinum und cisplatinum had been eliminated considerably by the experimental sewage plant, though in very variable amounts (elimination between 17 und 83% of initial concentration). Flocculation, reduced the initial concentration by only 12%. Similar to the fluoroquinolones, the platinum compounds where sorbed on activated carbon. This seems to be the best way for their elimination, while the technical polymer Lewatit‐EP63 showed no adsorption at all.
AB - The elimination potential of two classes of pharmaceuticals in water treatment was examined. Substances representative for the fluoroquinolones, ofloxacine and levofloxacine, showed no reduction in concentration during passage through a model sewage plant working with sewage sludge from a municipal waste water treatment plant. Formation of metabolites, also produced by humans, was found only to a minor extent. However, adsorption on activated carbon showed convenient isotherms for water treatment. As expected, results were better with powdered activated carbon compared to granulous F300. Only poor adsorption was found for the technical polymer Lewatit EP63 as sorbent.The cytotoxic substances carboplatinum und cisplatinum had been eliminated considerably by the experimental sewage plant, though in very variable amounts (elimination between 17 und 83% of initial concentration). Flocculation, reduced the initial concentration by only 12%. Similar to the fluoroquinolones, the platinum compounds where sorbed on activated carbon. This seems to be the best way for their elimination, while the technical polymer Lewatit‐EP63 showed no adsorption at all.
KW - Carboplatin
KW - Cisplatin
KW - elimination
KW - Levofloxacin
KW - pharmazeutische Stoffe
KW - Ofloxacin
KW - Wasseraufbereitung
KW - Zytostatikum
KW - Verhalten
KW - Chemie
UR - https://www.mendeley.com/catalogue/58870f68-a999-34b5-bd0c-6dc19d810f77/
U2 - 10.1002/3527600892.ch9
DO - 10.1002/3527600892.ch9
M3 - Zeitschriftenaufsätze
VL - 100
SP - 155
EP - 168
JO - Vom Wasser
JF - Vom Wasser
SN - 0083-6915
ER -