Verhalten von Arzneimitteln in der Wasseraufbereitung: Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika

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Verhalten von Arzneimitteln in der Wasseraufbereitung: Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika. / Brückner-Nieder, Uta; Frimmel, Fritz H.; Hüttig, Jana et al.
in: Vom Wasser, Jahrgang 100, 2003, S. 155-168.

Publikation: Beiträge in ZeitschriftenZeitschriftenaufsätzeForschungbegutachtet

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@article{a8a116ffd93b4dd5bf9994eda42fb9ef,
title = "Verhalten von Arzneimitteln in der Wasseraufbereitung: Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika",
abstract = "The elimination potential of two classes of pharmaceuticals in water treatment was examined. Substances representative for the fluoroquinolones, ofloxacine and levofloxacine, showed no reduction in concentration during passage through a model sewage plant working with sewage sludge from a municipal waste water treatment plant. Formation of metabolites, also produced by humans, was found only to a minor extent. However, adsorption on activated carbon showed convenient isotherms for water treatment. As expected, results were better with powdered activated carbon compared to granulous F300. Only poor adsorption was found for the technical polymer Lewatit EP63 as sorbent.The cytotoxic substances carboplatinum und cisplatinum had been eliminated considerably by the experimental sewage plant, though in very variable amounts (elimination between 17 und 83% of initial concentration). Flocculation, reduced the initial concentration by only 12%. Similar to the fluoroquinolones, the platinum compounds where sorbed on activated carbon. This seems to be the best way for their elimination, while the technical polymer Lewatit‐EP63 showed no adsorption at all.",
keywords = "Carboplatin, Cisplatin, elimination, Levofloxacin, pharmazeutische Stoffe, Ofloxacin, Wasseraufbereitung, Zytostatikum, Verhalten, Chemie",
author = "Uta Br{\"u}ckner-Nieder and Frimmel, {Fritz H.} and Jana H{\"u}ttig and Klaus K{\"u}mmerer",
note = "Editors(s):Wasserschemische Gesellschaft, Fachgruppe in der Gesellschaft Deutscher ChemikerProf. Dr. Martin Jekel First published:15 July 2003 Print ISBN:9783527305667 |Online ISBN:9783527600892 |DOI:10.1002/3527600892 Copyright {\textcopyright} 2003 Wiley‐VCH Verlag GmbH & Co. KGaA",
year = "2003",
doi = "10.1002/3527600892.ch9",
language = "Deutsch",
volume = "100",
pages = "155--168",
journal = "Vom Wasser",
issn = "0083-6915",
publisher = "Wiley-VCH Verlag",

}

RIS

TY - JOUR

T1 - Verhalten von Arzneimitteln in der Wasseraufbereitung

T2 - Untersuchuchungen zur Elimination von Fluorchinolonen und platinhaltigen Zytostatika

AU - Brückner-Nieder, Uta

AU - Frimmel, Fritz H.

AU - Hüttig, Jana

AU - Kümmerer, Klaus

N1 - Editors(s):Wasserschemische Gesellschaft, Fachgruppe in der Gesellschaft Deutscher ChemikerProf. Dr. Martin Jekel First published:15 July 2003 Print ISBN:9783527305667 |Online ISBN:9783527600892 |DOI:10.1002/3527600892 Copyright © 2003 Wiley‐VCH Verlag GmbH & Co. KGaA

PY - 2003

Y1 - 2003

N2 - The elimination potential of two classes of pharmaceuticals in water treatment was examined. Substances representative for the fluoroquinolones, ofloxacine and levofloxacine, showed no reduction in concentration during passage through a model sewage plant working with sewage sludge from a municipal waste water treatment plant. Formation of metabolites, also produced by humans, was found only to a minor extent. However, adsorption on activated carbon showed convenient isotherms for water treatment. As expected, results were better with powdered activated carbon compared to granulous F300. Only poor adsorption was found for the technical polymer Lewatit EP63 as sorbent.The cytotoxic substances carboplatinum und cisplatinum had been eliminated considerably by the experimental sewage plant, though in very variable amounts (elimination between 17 und 83% of initial concentration). Flocculation, reduced the initial concentration by only 12%. Similar to the fluoroquinolones, the platinum compounds where sorbed on activated carbon. This seems to be the best way for their elimination, while the technical polymer Lewatit‐EP63 showed no adsorption at all.

AB - The elimination potential of two classes of pharmaceuticals in water treatment was examined. Substances representative for the fluoroquinolones, ofloxacine and levofloxacine, showed no reduction in concentration during passage through a model sewage plant working with sewage sludge from a municipal waste water treatment plant. Formation of metabolites, also produced by humans, was found only to a minor extent. However, adsorption on activated carbon showed convenient isotherms for water treatment. As expected, results were better with powdered activated carbon compared to granulous F300. Only poor adsorption was found for the technical polymer Lewatit EP63 as sorbent.The cytotoxic substances carboplatinum und cisplatinum had been eliminated considerably by the experimental sewage plant, though in very variable amounts (elimination between 17 und 83% of initial concentration). Flocculation, reduced the initial concentration by only 12%. Similar to the fluoroquinolones, the platinum compounds where sorbed on activated carbon. This seems to be the best way for their elimination, while the technical polymer Lewatit‐EP63 showed no adsorption at all.

KW - Carboplatin

KW - Cisplatin

KW - elimination

KW - Levofloxacin

KW - pharmazeutische Stoffe

KW - Ofloxacin

KW - Wasseraufbereitung

KW - Zytostatikum

KW - Verhalten

KW - Chemie

UR - https://www.mendeley.com/catalogue/58870f68-a999-34b5-bd0c-6dc19d810f77/

U2 - 10.1002/3527600892.ch9

DO - 10.1002/3527600892.ch9

M3 - Zeitschriftenaufsätze

VL - 100

SP - 155

EP - 168

JO - Vom Wasser

JF - Vom Wasser

SN - 0083-6915

ER -

DOI