This special issue introduces new crossdisciplinary, crosslevel, and cross-cultural perspectives on job design. The authors examine job design from the viewpoints of organizational behavior, sociology, economics, corporate strategy, entrepreneurship, and evolutionary psychology. They consider job design in the context of interpersonal interactions, teams, leadership, networks, occupations, organizational structures, national cultures, and institutional fields. They explore how employees take initiative to craft their jobs, negotiate idiosyncratic deals, and navigate entrepreneurial roles, corporate director roles, executive roles, and careers.