Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies

Research output: Journal contributionsJournal articlesResearchpeer-review

Standard

Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies. / Reynaud, Franceline; Tsapis, Nicolas ; Deyme, Michel et al.
In: Soft Matter, Vol. 7, No. 16, 21.08.2011, p. 7304-7312.

Research output: Journal contributionsJournal articlesResearchpeer-review

Harvard

Reynaud, F, Tsapis, N, Deyme, M, Vasconcelos, TG, Gueutin, C, Guterres, SS, Pohlmann, AR & Fattal , E 2011, 'Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies', Soft Matter, vol. 7, no. 16, pp. 7304-7312. https://doi.org/10.1039/C1SM05509G

APA

Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T. G., Gueutin, C., Guterres, S. S., Pohlmann, A. R., & Fattal , E. (2011). Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies. Soft Matter, 7(16), 7304-7312. https://doi.org/10.1039/C1SM05509G

Vancouver

Reynaud F, Tsapis N, Deyme M, Vasconcelos TG, Gueutin C, Guterres SS et al. Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies. Soft Matter. 2011 Aug 21;7(16):7304-7312. doi: 10.1039/C1SM05509G

Bibtex

@article{4de1597e453145f2a7201d1081cd8011,
title = "Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies",
abstract = "Chitosan, a natural polysaccharide obtained from chitin deacetylation, complexes with metal ions by coordination with the free electron pairs of amine groups. Based on this complexation mechanism, cross-linked chitosan-metal microparticles were prepared by spray drying using iron (II or III) or zinc ions and characterized in terms of size distribution and capacity to specifically adsorb ciprofloxacin. Chitosan-Zn(II) and chitosan-Fe(III) microparticles appear to adsorb more ciprofloxacin than plain chitosan or chitosan-Fe(II) microparticles. Adsorption isotherms for CH and CH–Fe(II) microparticles can be fitted by a single logarithm model (slope 1) with one ciprofloxacin per adsorption site, whereas for CH–Fe(II) and CH–Zn(II) microparticles, isotherms are bilogarithmic with an initial slope of 2, suggesting that a single adsorption site can bind two molecules of ciprofloxacin. In addition, the pseudo second order kinetic model fits well experimental data, proving that adsorption is mediated by a chemical reaction. CH–Fe(II) and CH–Zn(II) appear very promising for drug elimination, either from hospital waste water or from the gastrointestinal tract to prevent the emergence of antibiotic resistance.",
keywords = "Chemistry, Biology, Ciprofoloxacin, Sustainability Science",
author = "Franceline Reynaud and Nicolas Tsapis and Michel Deyme and Vasconcelos, {Tibiri{\c c}a G.} and Claire Gueutin and Guterres, {S{\'i}lvia S.} and Pohlmann, {Adriana R.} and Elias Fattal",
year = "2011",
month = aug,
day = "21",
doi = "10.1039/C1SM05509G",
language = "English",
volume = "7",
pages = "7304--7312",
journal = "Soft Matter",
issn = "1744-6848",
publisher = "Royal Society of Chemistry Publishing",
number = "16",

}

RIS

TY - JOUR

T1 - Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption

T2 - Kinetic and equilibrium studies

AU - Reynaud, Franceline

AU - Tsapis, Nicolas

AU - Deyme, Michel

AU - Vasconcelos, Tibiriça G.

AU - Gueutin, Claire

AU - Guterres, Sílvia S.

AU - Pohlmann, Adriana R.

AU - Fattal , Elias

PY - 2011/8/21

Y1 - 2011/8/21

N2 - Chitosan, a natural polysaccharide obtained from chitin deacetylation, complexes with metal ions by coordination with the free electron pairs of amine groups. Based on this complexation mechanism, cross-linked chitosan-metal microparticles were prepared by spray drying using iron (II or III) or zinc ions and characterized in terms of size distribution and capacity to specifically adsorb ciprofloxacin. Chitosan-Zn(II) and chitosan-Fe(III) microparticles appear to adsorb more ciprofloxacin than plain chitosan or chitosan-Fe(II) microparticles. Adsorption isotherms for CH and CH–Fe(II) microparticles can be fitted by a single logarithm model (slope 1) with one ciprofloxacin per adsorption site, whereas for CH–Fe(II) and CH–Zn(II) microparticles, isotherms are bilogarithmic with an initial slope of 2, suggesting that a single adsorption site can bind two molecules of ciprofloxacin. In addition, the pseudo second order kinetic model fits well experimental data, proving that adsorption is mediated by a chemical reaction. CH–Fe(II) and CH–Zn(II) appear very promising for drug elimination, either from hospital waste water or from the gastrointestinal tract to prevent the emergence of antibiotic resistance.

AB - Chitosan, a natural polysaccharide obtained from chitin deacetylation, complexes with metal ions by coordination with the free electron pairs of amine groups. Based on this complexation mechanism, cross-linked chitosan-metal microparticles were prepared by spray drying using iron (II or III) or zinc ions and characterized in terms of size distribution and capacity to specifically adsorb ciprofloxacin. Chitosan-Zn(II) and chitosan-Fe(III) microparticles appear to adsorb more ciprofloxacin than plain chitosan or chitosan-Fe(II) microparticles. Adsorption isotherms for CH and CH–Fe(II) microparticles can be fitted by a single logarithm model (slope 1) with one ciprofloxacin per adsorption site, whereas for CH–Fe(II) and CH–Zn(II) microparticles, isotherms are bilogarithmic with an initial slope of 2, suggesting that a single adsorption site can bind two molecules of ciprofloxacin. In addition, the pseudo second order kinetic model fits well experimental data, proving that adsorption is mediated by a chemical reaction. CH–Fe(II) and CH–Zn(II) appear very promising for drug elimination, either from hospital waste water or from the gastrointestinal tract to prevent the emergence of antibiotic resistance.

KW - Chemistry

KW - Biology

KW - Ciprofoloxacin

KW - Sustainability Science

UR - http://www.scopus.com/inward/record.url?scp=79961132289&partnerID=8YFLogxK

U2 - 10.1039/C1SM05509G

DO - 10.1039/C1SM05509G

M3 - Journal articles

VL - 7

SP - 7304

EP - 7312

JO - Soft Matter

JF - Soft Matter

SN - 1744-6848

IS - 16

ER -

DOI