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Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling

Research output: Journal contributions › Journal articles › Research › peer-review

Standard

Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling. / Hellwig, Veronika; Ju, Yu-Ming; Rogers, Jack D. et al.
In: Mycological Progress, Vol. 4, No. 1, 01.02.2005, p. 39-54.

Research output: Journal contributions › Journal articles › Research › peer-review

Harvard

Hellwig, V, Ju, Y-M, Rogers, JD, Fournier, J & Stadler, M 2005, 'Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling', Mycological Progress, vol. 4, no. 1, pp. 39-54. https://doi.org/10.1007/s11557-006-0108-6

APA

Hellwig, V., Ju, Y.-M., Rogers, J. D., Fournier, J., & Stadler, M. (2005). Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling. Mycological Progress, 4(1), 39-54. https://doi.org/10.1007/s11557-006-0108-6

Vancouver

Hellwig V, Ju YM, Rogers JD, Fournier J, Stadler M. Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling. Mycological Progress. 2005 Feb 1;4(1):39-54. doi: 10.1007/s11557-006-0108-6

Bibtex

@article{44996443ce83442e9b7f52f7b410572b,
title = "Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling",
abstract = "A novel azaphilone named hypomiltin was isolated by preparative reversed phase HPLC from the stromatal extract of the xylariaceous ascomycete Hypoxylon hypomiltum. Its chemical structure was determined by mass spectrometry and 2D nuclear magnetic resonance spectroscopy. Analytical HPLC profiling of stromatal crude extracts, using UV/visual (diode array) and mass spectrometric detection based on electrospray ionisation, revealed the presence of hypomiltin also in Hypoxylon intermedium, H. perforatum, H. trugodes, and Pulveria porrecta. In contrast, this compound was found neither in type ma- terial of H. hypomiltum var. lavandulocinereum nor in several further Hypoxylon species. Despite being chemically related to mitorubrin, hypomiltin never co-occurred with the latter compound and its derivatives. Characteristic secondary meta- bolite profiles of several further Hypoxylon species are correlated with the colours of their taxonomically significant KOH- extractable pigments. These species are divided into chemotypes, based on analytical HPLC data. The results point toward an extraordinary diversity of secondary metabolites in Hypoxylon.",
keywords = "Chemistry",
author = "Veronika Hellwig and Yu-Ming Ju and Rogers, {Jack D.} and Jacques Fournier and Marc Stadler",
year = "2005",
month = feb,
day = "1",
doi = "10.1007/s11557-006-0108-6",
language = "English",
volume = "4",
pages = "39--54",
journal = "Mycological Progress",
issn = "1617-416X",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling

AU - Hellwig, Veronika

AU - Ju, Yu-Ming

AU - Rogers, Jack D.

AU - Fournier, Jacques

AU - Stadler, Marc

PY - 2005/2/1

Y1 - 2005/2/1

N2 - A novel azaphilone named hypomiltin was isolated by preparative reversed phase HPLC from the stromatal extract of the xylariaceous ascomycete Hypoxylon hypomiltum. Its chemical structure was determined by mass spectrometry and 2D nuclear magnetic resonance spectroscopy. Analytical HPLC profiling of stromatal crude extracts, using UV/visual (diode array) and mass spectrometric detection based on electrospray ionisation, revealed the presence of hypomiltin also in Hypoxylon intermedium, H. perforatum, H. trugodes, and Pulveria porrecta. In contrast, this compound was found neither in type ma- terial of H. hypomiltum var. lavandulocinereum nor in several further Hypoxylon species. Despite being chemically related to mitorubrin, hypomiltin never co-occurred with the latter compound and its derivatives. Characteristic secondary meta- bolite profiles of several further Hypoxylon species are correlated with the colours of their taxonomically significant KOH- extractable pigments. These species are divided into chemotypes, based on analytical HPLC data. The results point toward an extraordinary diversity of secondary metabolites in Hypoxylon.

AB - A novel azaphilone named hypomiltin was isolated by preparative reversed phase HPLC from the stromatal extract of the xylariaceous ascomycete Hypoxylon hypomiltum. Its chemical structure was determined by mass spectrometry and 2D nuclear magnetic resonance spectroscopy. Analytical HPLC profiling of stromatal crude extracts, using UV/visual (diode array) and mass spectrometric detection based on electrospray ionisation, revealed the presence of hypomiltin also in Hypoxylon intermedium, H. perforatum, H. trugodes, and Pulveria porrecta. In contrast, this compound was found neither in type ma- terial of H. hypomiltum var. lavandulocinereum nor in several further Hypoxylon species. Despite being chemically related to mitorubrin, hypomiltin never co-occurred with the latter compound and its derivatives. Characteristic secondary meta- bolite profiles of several further Hypoxylon species are correlated with the colours of their taxonomically significant KOH- extractable pigments. These species are divided into chemotypes, based on analytical HPLC data. The results point toward an extraordinary diversity of secondary metabolites in Hypoxylon.

KW - Chemistry

UR - https://www.mendeley.com/catalogue/c0c6b041-0b6d-3b12-a573-b5766e78d89d/

U2 - 10.1007/s11557-006-0108-6

DO - 10.1007/s11557-006-0108-6

M3 - Journal articles

VL - 4

SP - 39

EP - 54

JO - Mycological Progress

JF - Mycological Progress

SN - 1617-416X

IS - 1

ER -

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DOI