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Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution

Research output: Journal contributions › Scientific review articles › Research

Standard

Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution. / Akhrimenko, Vladimir; Kümmerer, Klaus; Malato, Sixto et al.
In: Trends in Biotechnology, 2025.

Research output: Journal contributions › Scientific review articles › Research

Harvard

Akhrimenko, V, Kümmerer, K, Malato, S, Lertxundi, U & Orive, G 2025, 'Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution', Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2025.11.015

APA

Akhrimenko, V., Kümmerer, K., Malato, S., Lertxundi, U., & Orive, G. (in press). Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2025.11.015

Vancouver

Akhrimenko V, Kümmerer K, Malato S, Lertxundi U, Orive G. Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution. Trends in Biotechnology. 2025. doi: 10.1016/j.tibtech.2025.11.015

Bibtex

@article{454a37eb915344f396dab1e935562e2c,
title = "Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution",
abstract = "Pharmaceutical pollution, defined as the presence of antibiotics, antidepressants, antidiabetics, and other pharmaceuticals in the environment, is a ubiquitous problem. Active pharmaceutical ingredients (APIs), along with their metabolites and excipients, pose a threat to public health, biodiversity, and ecosystems. In response to this environmental challenge, European legislation has been updated to include certain APIs as priority pollutants and to require the installation of advanced wastewater treatment facilities capable of eliminating them. To deliver an effective response to pharmaceutical pollution, we believe it is essential to implement a combination of at-source and end-of-pipe solutions. In addition, cutting-edge biotechnological tools such as gene engineering, omics analysis, biosensors, and microfluidics have yet to realize their full potential in tackling pharmaceutical pollution.",
keywords = "advanced wastewater treatment, benign by design, ecotoxicology, omics, pharmaceutical pollution, phytoremediation, Chemistry",
author = "Vladimir Akhrimenko and Klaus K{\"u}mmerer and Sixto Malato and Unax Lertxundi and Gorka Orive",
note = "Publisher Copyright: {\textcopyright} 2025 Elsevier Ltd",
year = "2025",
doi = "10.1016/j.tibtech.2025.11.015",
language = "English",
journal = "Trends in Biotechnology",
issn = "0167-7799",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution

AU - Akhrimenko, Vladimir

AU - Kümmerer, Klaus

AU - Malato, Sixto

AU - Lertxundi, Unax

AU - Orive, Gorka

N1 - Publisher Copyright: © 2025 Elsevier Ltd

PY - 2025

Y1 - 2025

N2 - Pharmaceutical pollution, defined as the presence of antibiotics, antidepressants, antidiabetics, and other pharmaceuticals in the environment, is a ubiquitous problem. Active pharmaceutical ingredients (APIs), along with their metabolites and excipients, pose a threat to public health, biodiversity, and ecosystems. In response to this environmental challenge, European legislation has been updated to include certain APIs as priority pollutants and to require the installation of advanced wastewater treatment facilities capable of eliminating them. To deliver an effective response to pharmaceutical pollution, we believe it is essential to implement a combination of at-source and end-of-pipe solutions. In addition, cutting-edge biotechnological tools such as gene engineering, omics analysis, biosensors, and microfluidics have yet to realize their full potential in tackling pharmaceutical pollution.

AB - Pharmaceutical pollution, defined as the presence of antibiotics, antidepressants, antidiabetics, and other pharmaceuticals in the environment, is a ubiquitous problem. Active pharmaceutical ingredients (APIs), along with their metabolites and excipients, pose a threat to public health, biodiversity, and ecosystems. In response to this environmental challenge, European legislation has been updated to include certain APIs as priority pollutants and to require the installation of advanced wastewater treatment facilities capable of eliminating them. To deliver an effective response to pharmaceutical pollution, we believe it is essential to implement a combination of at-source and end-of-pipe solutions. In addition, cutting-edge biotechnological tools such as gene engineering, omics analysis, biosensors, and microfluidics have yet to realize their full potential in tackling pharmaceutical pollution.

KW - advanced wastewater treatment

KW - benign by design

KW - ecotoxicology

KW - omics

KW - pharmaceutical pollution

KW - phytoremediation

KW - Chemistry

UR - http://www.scopus.com/inward/record.url?scp=105025587776&partnerID=8YFLogxK

U2 - 10.1016/j.tibtech.2025.11.015

DO - 10.1016/j.tibtech.2025.11.015

M3 - Scientific review articles

C2 - 41419349

AN - SCOPUS:105025587776

JO - Trends in Biotechnology

JF - Trends in Biotechnology

SN - 0167-7799

ER -

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DOI

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