A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol

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A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol. / Rastogi, Tushar; Leder, Christoph; Kummerer, Klaus.
In: RSC Advances, Vol. 5, No. 1, 2015, p. 27-32.

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@article{b5dce93248774c4499087c0dcaa7d138,
title = "A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol",
abstract = "Micro-pollutants in general as well as pharmaceuticals in the environment (PIE) in particular are obstacles for sustainable chemistry and can be seen as one of the major challenges of the sustainable management of water resources and a threat to health, water and food safety. Recent research has shown that this problem cannot be solved with advanced effluent treatment. Therefore, new approaches are urgently needed. This includes the new design of molecules or the re-design of existing molecules that present the functionality needed for their application and that are improved with regards to their biodegradability in the environment after their intended use. This paper presents a new approach for generating, identifying and testing biodegradable and drug-like molecules.",
keywords = "Chemistry, Atenolol, Benign by design, Antenolol, Sustainable chemistry, Benign by design, Sustainability Science",
author = "Tushar Rastogi and Christoph Leder and Klaus Kummerer",
note = "Publisher Copyright: {\textcopyright} 2015 The Royal Society of Chemistry.",
year = "2015",
doi = "10.1039/C4RA10294K",
language = "English",
volume = "5",
pages = "27--32",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "1",

}

RIS

TY - JOUR

T1 - A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol

AU - Rastogi, Tushar

AU - Leder, Christoph

AU - Kummerer, Klaus

N1 - Publisher Copyright: © 2015 The Royal Society of Chemistry.

PY - 2015

Y1 - 2015

N2 - Micro-pollutants in general as well as pharmaceuticals in the environment (PIE) in particular are obstacles for sustainable chemistry and can be seen as one of the major challenges of the sustainable management of water resources and a threat to health, water and food safety. Recent research has shown that this problem cannot be solved with advanced effluent treatment. Therefore, new approaches are urgently needed. This includes the new design of molecules or the re-design of existing molecules that present the functionality needed for their application and that are improved with regards to their biodegradability in the environment after their intended use. This paper presents a new approach for generating, identifying and testing biodegradable and drug-like molecules.

AB - Micro-pollutants in general as well as pharmaceuticals in the environment (PIE) in particular are obstacles for sustainable chemistry and can be seen as one of the major challenges of the sustainable management of water resources and a threat to health, water and food safety. Recent research has shown that this problem cannot be solved with advanced effluent treatment. Therefore, new approaches are urgently needed. This includes the new design of molecules or the re-design of existing molecules that present the functionality needed for their application and that are improved with regards to their biodegradability in the environment after their intended use. This paper presents a new approach for generating, identifying and testing biodegradable and drug-like molecules.

KW - Chemistry

KW - Atenolol

KW - Benign by design

KW - Antenolol

KW - Sustainable chemistry

KW - Benign by design

KW - Sustainability Science

UR - http://www.scopus.com/inward/record.url?scp=84915821087&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/bf034beb-913a-3313-b3e8-71a4e9649c9b/

U2 - 10.1039/C4RA10294K

DO - 10.1039/C4RA10294K

M3 - Journal articles

VL - 5

SP - 27

EP - 32

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 1

ER -

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