A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol
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In: RSC Advances, Vol. 5, No. 1, 2015, p. 27-32.
Research output: Journal contributions › Journal articles › Research › peer-review
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TY - JOUR
T1 - A sustainable chemistry solution to the presence of pharmaceuticals and chemicals in the aquatic environment-the example of re-designing β-blocker Atenolol
AU - Rastogi, Tushar
AU - Leder, Christoph
AU - Kummerer, Klaus
N1 - Publisher Copyright: © 2015 The Royal Society of Chemistry.
PY - 2015
Y1 - 2015
N2 - Micro-pollutants in general as well as pharmaceuticals in the environment (PIE) in particular are obstacles for sustainable chemistry and can be seen as one of the major challenges of the sustainable management of water resources and a threat to health, water and food safety. Recent research has shown that this problem cannot be solved with advanced effluent treatment. Therefore, new approaches are urgently needed. This includes the new design of molecules or the re-design of existing molecules that present the functionality needed for their application and that are improved with regards to their biodegradability in the environment after their intended use. This paper presents a new approach for generating, identifying and testing biodegradable and drug-like molecules.
AB - Micro-pollutants in general as well as pharmaceuticals in the environment (PIE) in particular are obstacles for sustainable chemistry and can be seen as one of the major challenges of the sustainable management of water resources and a threat to health, water and food safety. Recent research has shown that this problem cannot be solved with advanced effluent treatment. Therefore, new approaches are urgently needed. This includes the new design of molecules or the re-design of existing molecules that present the functionality needed for their application and that are improved with regards to their biodegradability in the environment after their intended use. This paper presents a new approach for generating, identifying and testing biodegradable and drug-like molecules.
KW - Chemistry
KW - Atenolol
KW - Benign by design
KW - Antenolol
KW - Sustainable chemistry
KW - Benign by design
KW - Sustainability Science
UR - http://www.scopus.com/inward/record.url?scp=84915821087&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/bf034beb-913a-3313-b3e8-71a4e9649c9b/
U2 - 10.1039/C4RA10294K
DO - 10.1039/C4RA10294K
M3 - Journal articles
VL - 5
SP - 27
EP - 32
JO - RSC Advances
JF - RSC Advances
SN - 2046-2069
IS - 1
ER -