Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- 2024
- Published
Safe-and-sustainable-by-design roadmap: identifying research, competencies, and knowledge sharing needs
Apel, C., Sudheshwar, A., Kümmerer, K., Nowack, B., Midander, K., Strömberg, E. & Soeteman-Hernández, L. G., 19.08.2024, In: RSC Sustainability. 2, 10, p. 2833-2838 6 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Determination and risk assessment of UV filters and benzotriazole UV stabilizers in wastewater from a wastewater treatment plant in Lüneburg, Germany
Ajibola, A. S., Reich, M. & Kümmerer, K., 08.2024, In: Environmental Monitoring and Assessment. 196, 8, 19 p., 725.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
The urgent need for designing greener drugs
Brodin, T., Bertram, M. G., Arnold, K. E., Boxall, A. B. A., Brooks, B. W., Cerveny, D., Jörg, M., Kidd, K. A., Lertxundi, U., Martin, J. M., May, L. T., McCallum, E. S., Michelangeli, M., Tyler, C. R., Wong, B. B. M., Kümmerer, K. & Orive, G., 08.2024, In: Nature Sustainability. 7, 8, p. 949-951 3 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Biodegradation of Flavonoids – Influences of structural features
Schnarr, L., Olsson, O. & Kümmerer, K., 01.07.2024, In: Chemosphere. 359, 11 p., 142234.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Design of greener drugs: aligning parameters in pharmaceutical R&D and drivers for environmental impact
Vidaurre, R., Bramke, I., Puhlmann, N., Owen, S. F., Angst, D., Moermond, C., Venhuis, B., Lombardo, A., Kümmerer, K., Sikanen, T., Ryan, J., Häner, A., Janer, G., Roggo, S. & Perkins, A. N., 01.07.2024, In: Drug Discovery Today. 29, 7, 10 p., 104022.Research output: Journal contributions › Scientific review articles › Research
- E-pub ahead of print
Mainstreaming regenerative dynamics for sustainability
Fischer, J., Farny, S., Abson, D. J., Zuin Zeidler, V., von Salisch, M., Schaltegger, S., Martín-López, B., Temperton, V. M. & Kümmerer, K., 12.12.2024, In: Nature Sustainability. 7, p. 964–972Research output: Journal contributions › Scientific review articles › Research
- Published
Modelling biodegradability based on OECD 301D data for the design of mineralising ionic liquids
Amsel, A. K., Chakravarti, S., Olsson, O. & Kümmerer, K., 22.05.2024, In: Green Chemistry . 26, 12, p. 7363-7376 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Impact of green and blue-green light on the growth, pigment concentration, and fatty acid unsaturation in the microalga Monoraphidium braunii
Helamieh, M., Reich, M., Rohne, P., Riebesell, U., Kerner, M. & Kümmerer, K., 01.05.2024, In: Photochemistry and Photobiology. 100, 3, p. 587-595 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
How data on transformation products can support the redesign of sulfonamides towards better biodegradability in the environment
Puhlmann, N., Olsson, O. & Kümmerer, K., 15.04.2024, In: Science of the Total Environment. 921, 13 p., 171027.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Flavonoids as benign substitutes for more harmful synthetic chemicals - effects of flavonoids and their transformation products on algae
Schnarr, L., Olsson, O., Ohls, S., Webersinn, J., Mauch, T. & Kümmerer, K., 01.04.2024, In: Sustainable Chemistry and Pharmacy. 38, 19 p., 101473.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Analysis of environmental biodegradability of cellulose-based pharmaceutical excipients in aqueous media
Bading, M., Olsson, O. & Kümmerer, K., 01.03.2024, In: Chemosphere. 352, 8 p., 141298.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Safe-and-sustainable-by-design: State of the art approaches and lessons learned from value chain perspectives
Apel, C., Kümmerer, K., Sudheshwar, A., Nowack, B., Som, C., Colin, C., Walter, L., Breukelaar, J., Meeus, M., Ildefonso, B., Petrovykh, D., Elyahmadi, C., Huttunen-Saarivirta, E., Dierckx, A., Devic, A. C., Valsami-Jones, E., Brennan, M., Rocca, C., Scheper, J., Strömberg, E. & Soeteman-Hernández, L. G., 01.02.2024, In: Current Opinion in Green and Sustainable Chemistry. 45, 16 p., 100876.Research output: Journal contributions › Scientific review articles › Research
- Published
Designing greener active pharmaceutical ingredients: Insights from pharmaceutical industry into drug discovery and development
Puhlmann, N., Vidaurre, R. & Kümmerer, K., 01.01.2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106614.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Learning from Safe-by-Design for Safe-and-Sustainable-by-Design: Mapping the Current Landscape of Safe-by-Design Reviews, Case Studies, and Frameworks
Sudheshwar, A., Apel, C., Kümmerer, K., Wang, Z., Soeteman-Hernández, L. G., Valsami-Jones, E., Som, C. & Nowack, B., 01.01.2024, In: Environment international. 183, 13 p., 108305.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa
Nantaba, F., Wasswa, J., Kylin, H., Bouwman, H., Palm, W-U. & Kümmerer, K., 01.01.2024, In: Science of the Total Environment. 906, 10 p., 167348.Research output: Journal contributions › Journal articles › Research › peer-review
- 2023
- Published
Nile Red as a Fluorescence Marker and Antioxidant for Regenerative Fuels
Lichtinger, A., Poller, M. J., Türck, J., Schröder, O., Garbe, T., Krahl, J., Singer, A., Jakob, M. & Albert, J., 11.2023, In: Energy Technology. 11, 11, 9 p., 2300260.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Status quo on identified transformation products of organic ultraviolet filters and their persistence
Jentzsch, F., Kümmerer, K. & Olsson, O., 10.2023, In: International Journal of Cosmetic Science. 45, S1, p. 101-126 26 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Identification of structure-biodegradability relationships for ionic liquids - clustering of a dataset based on structural similarity
Amsel, A. K., Olsson, O. & Kümmerer, K., 29.09.2023, In: Green Chemistry . 25, 22, p. 9226-9250 25 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Are Si–C bonds formed in the environment and/or in technical microbiological systems?
Rücker, C., Winkelmann, M. & Kümmerer, K., 08.2023, In: Environmental Science and Pollution Research. 30, 39, p. 91492-91500 9 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methods
Escher, B. I., Altenburger, R., Blüher, M., Colbourne, J. K., Ebinghaus, R., Fantke, P., Hein, M., Köck, W., Kümmerer, K., Leipold, S., Li, X., Scheringer, M., Scholz, S., Schloter, M., Schweizer, P. J., Tal, T., Tetko, I., Traidl-Hoffmann, C., Wick, L. Y. & Fenner, K., 01.05.2023, In: Archives of Toxicology. 97, 5, p. 1267-1283 17 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Are Si-C bonds cleaved by microorganisms? A critical review on biodegradation of methylsiloxanes
Rücker, C., Grabitz, E. & Kümmerer, K., 01.04.2023, In: Chemosphere. 321, 137858.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Identification of environmentally biodegradable scaffolds for the benign design of quinolones and related substances
Suk, M., Lorenz, S. & Kümmerer, K., 01.04.2023, In: Sustainable Chemistry and Pharmacy. 31, 100947.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
A kinetic study of the photolysis of sulfamethoxazole with special emphasis on the photoisomer
Palm, W. U., Schmidt, N., Stahn, M. & Grimme, S., 01.03.2023, In: Photochemical and Photobiological Sciences. 22, 3, p. 615-630 16 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Environmental degradation of human metabolites of cyclophosphamide leads to toxic and non-biodegradable transformation products
Suk, M. & Kümmerer, K., 20.01.2023, In: Science of the Total Environment. 857, Part 3, 159454.Research output: Journal contributions › Journal articles › Research
- Published
Towards greener and sustainable ionic liquids using naturally occurring and nature-inspired pyridinium structures
Suk, M. & Kümmerer, K., 07.01.2023, In: Green Chemistry . 25, 1, p. 365-374 10 p., 25.Research output: Journal contributions › Journal articles › Research › peer-review
- 2022
- Published
Für eine neue Ganzheitlichkeit: Nachhaltige Chemie
Kümmerer, K. & Große Ophoff, M., 28.12.2022, In: Politische Ökologie. 40, 171, p. 90 - 96 7 p.Research output: Journal contributions › Journal articles › Transfer
- Published
Designing benign molecules: The influence of O-acetylated glucosamine-substituents on the environmental biodegradability of fluoroquinolones
Lorenz, S., Suaifan, G. & Kümmerer, K., 01.12.2022, In: Chemosphere. 309, Part 2, 136724.Research output: Journal contributions › Journal articles › Research
- Published
One planet: one health. A call to support the initiative on a global science–policy body on chemicals and waste
Brack, W., Barcelo Culleres, D., Boxall, A. B. A., Budzinski, H., Castiglioni, S., Covaci, A., Dulio, V., Escher, B. I., Fantke, P., Kandie, F., Fatta-Kassinos, D., Hernández, F. J., Hilscherová, K., Hollender, J., Hollert, H., Jahnke, A., Kasprzyk-Hordern, B., Khan, S. J., Kortenkamp, A., Kümmerer, K., Lalonde, B., Lamoree, M. H., Levi, Y., Lara Martín, P. A., Montagner, C. C., Mougin, C., Msagati, T., Oehlmann, J., Posthuma, L., Reid, M., Reinhard, M., Richardson, S. D., Rostkowski, P., Schymanski, E., Schneider, F., Slobodnik, J., Shibata, Y., Snyder, S. A., Fabriz Sodré, F., Teodorovic, I., Thomas, K. V., Umbuzeiro, G. A., Viet, P. H., Yew-Hoong, K. G., Zhang, X. & Zuccato, E., 01.12.2022, In: Environmental Sciences Europe. 34, 1, 10 p., 21.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Discharge and fate of biocide residuals to ephemeral stormwater retention pond sediments
Linke, F., Olsson, O., Schnarr, L., Kümmerer, K., Preusser, F., Bork, M., Leistert, H. & Lange, J., 01.11.2022, In: Hydrology Research. 53, 11, p. 1441-1453 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Quantum chemical calculation of the vapor pressure of volatile and semi volatile organic compounds
Stahn, M., Grimme, S., Salthammer, T., Hohm, U. & Palm, W-U., 03.10.2022, In: Environmental Sciences: Processes & Impacts. 24, 11, p. 2153-2166 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Improving the end-of-life management of solar panels in Germany
El-Khawad, L., Bartkowiak, D. & Kümmerer, K., 01.10.2022, In: Renewable and Sustainable Energy Reviews. 168, 112678.Research output: Journal contributions › Journal articles › Research
- Published
The lipid composition of the in situ pellicle
Reich, M., Hannig, C., Hannig, M., Kümmerer, K. & Kensche, A., 01.10.2022, In: Archives of Oral Biology. 142, 105493.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Ionic liquids vs. ethanol as extraction media of algicidal compounds from mango processing waste
Segatto, M. L., Schnarr, L., Olsson, O., Kümmerer, K. & Zuin, V. G., 16.09.2022, In: Frontiers in Chemistry. 10, 13 p., 986987.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
GREENER Pharmaceuticals for More Sustainable Healthcare
Moermond, C. T. A., Puhlmann, N., Brown, A. R., Owen, S. F., Ryan, J., Snape, J., Venhuis, B. J. & Kümmerer, K., 13.09.2022, In: Environmental Science and Technology Letters. 9, 9, p. 699-705 7 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Repurposing chemical waste: Sustainable chemistry for circularity beyond artificial intelligence
Zuin, V. G. & Kümmerer, K., 21.07.2022, In: Cell. 185, 15, p. 2655-2656 2 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Transformation products of sulfonamides in aquatic systems: Lessons learned from available environmental fate and behaviour data
Puhlmann, N., Olsson, O. & Kümmerer, K., 15.07.2022, In: Science of the Total Environment. 830, 16 p., 154744.Research output: Journal contributions › Scientific review articles › Research
- Published
Blue-green light is required for a maximized fatty acid unsaturation and pigment concentration in the microalga Acutodesmus obliquus
Helamieh, M., Reich, M., Bory, S., Rohne, P., Riebesell, U., Kerner, M. & Kümmerer, K., 01.07.2022, In: Lipids. 57, 4-5, p. 221-232 12 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Inventory of biodegradation data of ionic liquids
Amsel, A. K., Olsson, O. & Kümmerer, K., 01.07.2022, In: Chemosphere. 299, 134385.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Flavonoids as biopesticides – Systematic assessment of sources, structures, activities and environmental fate
Schnarr, L., Segatto, M. L., Olsson, O., Zuin, V. G. & Kümmerer, K., 10.06.2022, In: Science of the Total Environment. 824, 153781.Research output: Journal contributions › Scientific review articles › Research
- Published
A scale-up procedure to dialkyl carbonates; evaluation of their properties, biodegradability, and toxicity
Trapasso, G., Salaris, C., Reich, M., Logunova, E., Salata, C., Kümmerer, K., Figoli, A. & Aricò, F., 01.05.2022, In: Sustainable Chemistry and Pharmacy. 26, 100639.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
In search of the Holy Grail of Rodent control: Step-by-step implementation of safe and sustainable-by-design principles on the example of rodenticides
Hohenberger, J., Friesen, A., Wieck, S. & Kümmerer, K., 01.04.2022, In: Sustainable Chemistry and Pharmacy. 25, 19 p., 100602.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Chemistry and materials science for a sustainable circular polymeric economy
Zuin Zeidler, V. G. & Kümmerer, K., 01.02.2022, In: Nature Reviews Materials. 7, 2, p. 76-78 3 p.Research output: Journal contributions › Comments / Debate / Reports › Research
- Published
Quantum Chemical Calculation and Evaluation of Partition Coefficients for Classical and Emerging Environmentally Relevant Organic Compounds
Salthammer, T., Grimme, S., Stahn, M., Hohm, U. & Palm, W. U., 04.01.2022, In: Environmental Science and Technology. 56, 1, p. 379-391 13 p.Research output: Journal contributions › Journal articles › Research › peer-review
- 2021
- Published
The contribution of material circularity to sustainability—Recycling and reuse of textiles
Keßler, L., Matlin, S. A. & Kümmerer, K., 01.12.2021, In: Current Opinion in Green and Sustainable Chemistry. 32, 10 p., 100535.Research output: Journal contributions › Scientific review articles › Research
- Published
Toward Application and Implementation of in Silico Tools and Workflows within Benign by Design Approaches
Lorenz, S., Amsel, A. K., Puhlmann, N., Reich, M., Olsson, O. & Kümmerer, K., 20.09.2021, In: ACS Sustainable Chemistry and Engineering. 9, 37, p. 12461-12475 15 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Towards the design of organosilicon compounds for environmental degradation by using structure biodegradability relationships
Grabitz, E., Olsson, O. & Kümmerer, K., 01.09.2021, In: Chemosphere. 279, 12 p., 130442.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Growth and fatty acid composition of Acutodesmus obliquus under different light spectra and temperatures
Helamieh, M., Gebhardt, A., Reich, M., Kuhn, F., Kerner, M. & Kümmerer, K., 09.2021, In: Lipids. 56, 5, p. 485-498 14 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Sources and pathways of biocides and their transformation products in urban storm water infrastructure of a 2 ha urban district
Linke, F., Olsson, O., Preusser, F., Kümmerer, K., Schnarr, L., Bork, M. & Lange, J., 20.08.2021, In: Hydrology and Earth System Sciences. 25, 8, p. 4495-4512 18 p.Research output: Journal contributions › Journal articles › Research › peer-review
- Published
Towards the design of active pharmaceutical ingredients mineralizing readily in the environment
Puhlmann, N., Mols, R., Olsson, O., Slootweg, J. C. & Kümmerer, K., 21.07.2021, In: Green Chemistry . 23, 14, p. 5006-5023 18 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Reducing Environmental Pollution by Antibiotics through Design for Environmental Degradation
Leder, C., Suk, M., Lorenz, S., Rastogi, T., Pfeifer, C., Kietzmann, M., Jonas, D., Buck, M., Pahl, A. & Kümmerer, K., 19.07.2021, In: ACS Sustainable Chemistry & Engineering. 9, 28, p. 9358–9368 11 p.Research output: Journal contributions › Journal articles › Research › peer-review