Professorship for Sustainable Chemistry and Material Resources
Organisational unit: Section
Organisation profile
RESEARCH AND TEACHING
Chair for Sustainable Chemistry and Material Resources
We research and train in the field of sustainable chemistry and pharmacy.
We focus on environmental questions as well as on sustainable questions going beyond that such as social and ecological aspects in the context of the life cycle of chemical substances and products. This includes the extraction of raw material, its use as well as the fate after its use. We are also interested in the material flow associated with the extraction and use of the raw material. On top of the experimental work and modeling, we also develop concepts as for example Benign by Design intended dissipation.
Our research and teaching is carried out on an intra- and transdisciplinary scale within the Faculty of Sustainability together with national and international co-operations.
Topics
We are interested in environmental affairs and all questions concerning the sustainability within the context of the life cycle of chemicals, starting with the raw material itself and going on to the synthesis, the use to end up with the environmental fate of chemical substances and products after their use. Beyond the chemical substances and products themselves, we are also interested in the associated material flows, especially when it comes to the so-called strategic resources (e. g. phosphate, seldom metals).
We investigate the fate (e. g. identification of relevant sources) in the environment as well as the spread and the behavior of chemicals (e. g. spread, biological and photochemical degradation) in the aquatic environment in the sense of a sustainable water management. This is why we want to record their effects (e. g. genotoxicity, mutagenity, and bacteria toxicity).At present we are focusing on pesticides, pharmaceuticals, textile auxiliary agents and nanoparticles.
Service offers
Examination of (bio)-degradability of chemicals and pharmaceuticals
according to OECD/DIN/ISO and others:
• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test
• Photochemical degradation
• Photocatalytic degradation
• Electro coalugation
• and other
Toxicity
Acute and chronic toxicity in bacteria:
• Luminescent bacteria test with Vibrio fischeri (30 minutes and 20h)
• Growth-inhibition test with Pseudomonas putida (16h) and Vibrio fischeri (20h)
• Growth-inhibition test with Enteroccus faecalis
Genotoxicity:
• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis
• Green Screen-Assay with TK6-cells
Chemical informatics
Structure property relationships
• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and mutagenicity
• Calculation of the biological degradation
• Calculation of metabolites (mammalia bacteria)
• Targeted design of chemicals and pharmaceuticals
• Support in purchasing decisions
• Product optimization
• REACH
Water flux based reactive mass transport modelling and assessment
• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation product discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water ressources management
Analytics
• Liquid chromatography coupled to ion trap mass spectrometry
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
- Scientific review articles › Research
- Published
A path to clean water: Reduced chemicals input must complement wastewater treatment to ensure the safety of water resources
Kümmerer, K., Dionysiou, D. D., Olsson, O. & Fatta-Kassinos, D., 20.07.2018, In: Science. 361, 6399, p. 222 - 224 3 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Application of titanium dioxide nanoparticles as a photocatalyst for the removal of micropollutants such as pharmaceuticals from water
Mahmoud, W. M. M., Rastogi, T. & Kümmerer, K., 01.08.2017, In: Current Opinion in Green and Sustainable Chemistry. 6, p. 1-10 10 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Consequences of nuclear accidents for biodiversity and ecosystem services
von Wehrden, H., Fischer, J., Brandt, P., Wagner, V., Kümmerer, K., Kuemmerle, T., Nagel, A., Olsson, O. & Hostert, P., 01.04.2012, In: Conservation Letters. 5, 2, p. 81-89 9 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Design of greener drugs: aligning parameters in pharmaceutical R&D and drivers for environmental impact
Vidaurre, R., Bramke, I., Puhlmann, N., Owen, S. F., Angst, D., Moermond, C., Venhuis, B., Lombardo, A., Kümmerer, K., Sikanen, T., Ryan, J., Häner, A., Janer, G., Roggo, S. & Perkins, A. N., 01.07.2024, In: Drug Discovery Today. 29, 7, 10 p., 104022.Research output: Journal contributions › Scientific review articles › Research
- Published
Emerging risks from ballast water treatment: The run-up to the International Ballast Water Management Convention
Werschkun, B., Banerji, S., Basurko, O. C., David, M., Fuhr, F., Gollasch, S., Grummt, T., Haarich, M., Jha, A. N., Kacan, S., Kehrer, A., Linders, J., Mesbahi, E., Pughiuc, D., Richardson, S. D., Schwarz-Schulz, B., Shah, A., Theobald, N., von Gunten, U., Wieck, S. & Höfer, T., 01.10.2014, In: Chemosphere. 112, p. 256-266 11 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental chemistry of organosiloxanes
Rücker, C. & Kümmerer, K., 14.01.2015, In: Chemical Reviews. 115, 1, p. 466-524 59 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental risk assessment of anti-cancer drugs and their transformation products: a focus on their genotoxicity characterization-state of knowledge and short comings
Toolaram, A. P., Kümmerer, K. & Schneider, M., 04.2014, In: Mutation Research. 760, p. 18-35 18 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Environmental side effects of pharmaceutical cocktails: What we know and what we should know
Vasquez, M. I., Lambrianides, A., Schneider, M., Kümmerer, K. & Fatta-Kassinos, D., 30.08.2014, In: Journal of Hazardous Materials. 279, p. 169-189 21 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Flavonoids as biopesticides – Systematic assessment of sources, structures, activities and environmental fate
Schnarr, L., Segatto, M. L., Olsson, O., Zuin, V. G. & Kümmerer, K., 10.06.2022, In: Science of the Total Environment. 824, 153781.Research output: Journal contributions › Scientific review articles › Research
- Published
From a problem to a business opportunity-design of pharmaceuticals for environmental biodegradability
Kümmerer, K., 06.2019, In: Sustainable Chemistry and Pharmacy. 12, 4 p., 100136.Research output: Journal contributions › Scientific review articles › Research
- Published
GREENER Pharmaceuticals for More Sustainable Healthcare
Moermond, C. T. A., Puhlmann, N., Brown, A. R., Owen, S. F., Ryan, J., Snape, J., Venhuis, B. J. & Kümmerer, K., 13.09.2022, In: Environmental Science and Technology Letters. 9, 9, p. 699-705 7 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Lipids in preventive dentistry
Kensche, A., Reich, M., Kümmerer, K., Hannig, M. & Hannig, C., 04.2013, In: Clinical Oral Investigations. 17, 3, p. 669-685 17 p.Research output: Journal contributions › Scientific review articles › Research
- Accepted/In press
Mainstreaming regenerative dynamics for sustainability
Fischer, J., Farny, S., Abson, D. J., Zuin Zeidler, V., von Salisch, M., Schaltegger, S., Martín-López, B., Temperton, V. M. & Kümmerer, K., 2024, (Accepted/In press) In: Nature Sustainability.Research output: Journal contributions › Scientific review articles › Research
- E-pub ahead of print
Mainstreaming regenerative dynamics for sustainability
Fischer, J., Farny, S., Abson, DJ., Zeidler, VZ., von Salisch, M., Schaltegger, S., Martín-López, B., Temperton, VM. & Kümmerer, K., 12.06.2024, (E-pub ahead of print) In: Nature Sustainability. 9 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Material circularity and the role of the chemical sciences as a key enabler of a sustainable post-trash age
Matlin, S. A., Mehta, G., Hopf, H., Krief, A., Keßler, L. & Kümmerer, K., 01.09.2020, In: Sustainable Chemistry and Pharmacy. 17, 11 p., 100312.Research output: Journal contributions › Scientific review articles › Research
- Published
Modeling and predicting aquatic aerobic biodegradation: a review from a user’s perspective.
Rücker, C. & Kümmerer, K., 04.2012, In: Green Chemistry . 14, 4, p. 875-887 13 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Plasmid DNA vaccines against cancer. Cytotoxic T-lymphocyte induction against tumor antigens
Pavlenko, M., Leder, C. & Pisa, P., 01.06.2005, In: Expert Review of Vaccines. 4, 3, p. 315-327 13 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Rethinking Chemistry for a circular economy
Kümmerer, K., Clark, J. & Zuin, V. G., 23.01.2020, In: Science. 367, 6476, p. 369 - 370 2 p.Research output: Journal contributions › Scientific review articles › Research
- Published
Safe-and-sustainable-by-design: State of the art approaches and lessons learned from value chain perspectives
Apel, C., Kümmerer, K., Sudheshwar, A., Nowack, B., Som, C., Colin, C., Walter, L., Breukelaar, J., Meeus, M., Ildefonso, B., Petrovykh, D., Elyahmadi, C., Huttunen-Saarivirta, E., Dierckx, A., Devic, A. C., Valsami-Jones, E., Brennan, M., Rocca, C., Scheper, J., Strömberg, E. & Soeteman-Hernández, L. G., 01.02.2024, In: Current Opinion in Green and Sustainable Chemistry. 45, 16 p., 100876.Research output: Journal contributions › Scientific review articles › Research
- Published
Scope of the book wastewater reuse and current challenges
Kümmerer, K., Dionysiou, D. D. & Fatta-Kassinos, D., 2016, In: Handbook of Environmental Chemistry. 44, p. 1-5 5 p.Research output: Journal contributions › Scientific review articles › Research