The present chapter reviews moderators of the ego depletion effect. We organize the plethora of moderators in a two-factor organizing grid in terms of (1) timing and (2) leverage point. The timing factor distinguishes moderators that are active before the start of the first demanding task in the typical dual-task paradigm versus those that are experimentally activated after the first (and before the second) task. The leverage point factor distinguishes whether factors exert their moderating influence through situational state differences of a person, through the (first or second) demanding task itself, or via interpersonal trait differences. We discuss how the reviewed moderators contribute to the debate about underlying processes of the ego depletion effect and how their moderating roles can be explained from the perspectives of two prominent and competing models—the strength model and the process model of self-control.