TY - JOUR

T1 - Anatomical and neuromuscular variables strongly predict maximum knee extension torque in healthy men

AU - Trezise, J.

AU - Collier, N.

AU - Blazevich, A. J.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Purpose: This study examined the relative influence of anatomical and neuromuscular variables on maximal isometric and concentric knee extensor torque and provided a comparative dataset for healthy young males. Methods: Quadriceps cross-sectional area (CSA) and fascicle length (lf) and angle (θf) from the four quadriceps components; agonist (EMG:M) and antagonist muscle activity, and percent voluntary activation (%VA); patellar tendon moment arm distance (MA) and maximal voluntary isometric and concentric (60° s−1) torques, were measured in 56 men. Linear regression models predicting maximum torque were ranked using Akaike’s Information Criterion (AICc), and Pearson’s correlation coefficients assessed relationships between variables. Results: The best-fit models explained up to 72 % of the variance in maximal voluntary knee extension torque. The combination of ‘CSA + θf + EMG:M + %VA’ best predicted maximum isometric torque (R2 = 72 %, AICc weight = 0.38) and ‘CSA + θf + MA’ (R2 = 65 %, AICc weight = 0.21) best predicted maximum concentric torque. Conclusion: Proximal quadriceps CSA was included in all models rather than the traditionally used mid-muscle CSA. Fascicle angle appeared consistently in all models despite its weak correlation with maximum torque in isolation, emphasising the importance of examining interactions among variables. While muscle activity was important for torque prediction in both contraction modes, MA only strongly influenced maximal concentric torque. These models identify the main sources of inter-individual differences strongly influencing maximal knee extension torque production in healthy men. The comparative dataset allows the identification of potential variables to target (i.e. weaknesses) in individuals.

AB - Purpose: This study examined the relative influence of anatomical and neuromuscular variables on maximal isometric and concentric knee extensor torque and provided a comparative dataset for healthy young males. Methods: Quadriceps cross-sectional area (CSA) and fascicle length (lf) and angle (θf) from the four quadriceps components; agonist (EMG:M) and antagonist muscle activity, and percent voluntary activation (%VA); patellar tendon moment arm distance (MA) and maximal voluntary isometric and concentric (60° s−1) torques, were measured in 56 men. Linear regression models predicting maximum torque were ranked using Akaike’s Information Criterion (AICc), and Pearson’s correlation coefficients assessed relationships between variables. Results: The best-fit models explained up to 72 % of the variance in maximal voluntary knee extension torque. The combination of ‘CSA + θf + EMG:M + %VA’ best predicted maximum isometric torque (R2 = 72 %, AICc weight = 0.38) and ‘CSA + θf + MA’ (R2 = 65 %, AICc weight = 0.21) best predicted maximum concentric torque. Conclusion: Proximal quadriceps CSA was included in all models rather than the traditionally used mid-muscle CSA. Fascicle angle appeared consistently in all models despite its weak correlation with maximum torque in isolation, emphasising the importance of examining interactions among variables. While muscle activity was important for torque prediction in both contraction modes, MA only strongly influenced maximal concentric torque. These models identify the main sources of inter-individual differences strongly influencing maximal knee extension torque production in healthy men. The comparative dataset allows the identification of potential variables to target (i.e. weaknesses) in individuals.

KW - Cross-sectional area

KW - Fascicle angle

KW - Linear models

KW - Moment arm distance

KW - Muscle activity

KW - Strength

KW - Sustainability Science

UR - http://www.scopus.com/inward/record.url?scp=84963677412&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/55aeda64-0df1-3557-b611-fb05a8eca8fb/

U2 - 10.1007/s00421-016-3352-8

DO - 10.1007/s00421-016-3352-8

M3 - Journal articles

C2 - 27076217

AN - SCOPUS:84963677412

VL - 116

SP - 1159

EP - 1177

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

IS - 6

ER -