Uthethane dimethacrylate: A molecule that may cause confusion in dental research
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Uthethane dimethacrylate: A molecule that may cause confusion in dental research. / Polydorou, Olga; König, Armin; Hellwig, Elmar et al.
In: Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 91B, No. 1, 01.10.2009, p. 1-4.Research output: Journal contributions › Journal articles › Research › peer-review
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TY - JOUR
T1 - Uthethane dimethacrylate: A molecule that may cause confusion in dental research
AU - Polydorou, Olga
AU - König, Armin
AU - Hellwig, Elmar
AU - Kümmerer, Klaus
N1 - (c) 2009 Wiley Periodicals, Inc.
PY - 2009/10/1
Y1 - 2009/10/1
N2 - In recent years, the elution of monomers from dental materials has been a cause for public concern. Urethane dimethacrylate, commonly abbreviated to UDMA, is one of the monomers that are most often tested with regard to elution from and cytotoxicity of resin-based materials. Although each chemical name represents the chemical type, chemical structure, and molecular weight of a molecule, it does not seem to be the same with UDMA. In the present paper, the different forms of UDMA are presented. These include those used by dental manufacturers to produce composite materials and the different types of urethane dimethacrylate used in studies concerning the elution of monomers from composite materials. High-performance liquid chromatography (HPLC) is usually used to detect the eluted monomers, but it does not appear to be adequate in determining the different forms of UDMA. The combination of HPLC with mass spectrometry is shown to be able to specifically identify the compounds eluted in addition to those compounds used as standards in the various studies. The fact that the same name is given to different molecules causes confusion about the results of studies testing the elusion of monomers from composite materials and their possible toxicity. © 2009 Wiley Periodicals, Inc.
AB - In recent years, the elution of monomers from dental materials has been a cause for public concern. Urethane dimethacrylate, commonly abbreviated to UDMA, is one of the monomers that are most often tested with regard to elution from and cytotoxicity of resin-based materials. Although each chemical name represents the chemical type, chemical structure, and molecular weight of a molecule, it does not seem to be the same with UDMA. In the present paper, the different forms of UDMA are presented. These include those used by dental manufacturers to produce composite materials and the different types of urethane dimethacrylate used in studies concerning the elution of monomers from composite materials. High-performance liquid chromatography (HPLC) is usually used to detect the eluted monomers, but it does not appear to be adequate in determining the different forms of UDMA. The combination of HPLC with mass spectrometry is shown to be able to specifically identify the compounds eluted in addition to those compounds used as standards in the various studies. The fact that the same name is given to different molecules causes confusion about the results of studies testing the elusion of monomers from composite materials and their possible toxicity. © 2009 Wiley Periodicals, Inc.
KW - Biocompatible Materials
KW - Dental Materials
KW - Humans
KW - Methacrylates
KW - Molecular Structure
KW - Polyurethanes
KW - Resin Cements
KW - Chemistry
UR - http://www.scopus.com/inward/record.url?scp=70049116401&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/1f09e9f8-10f8-3d69-9441-c27b147df466/
U2 - 10.1002/jbm.b.31383
DO - 10.1002/jbm.b.31383
M3 - Journal articles
C2 - 19388089
VL - 91B
SP - 1
EP - 4
JO - Journal of Biomedical Materials Research - Part B Applied Biomaterials
JF - Journal of Biomedical Materials Research - Part B Applied Biomaterials
SN - 1552-4973
IS - 1
ER -