New methods for in vivo degradation testing of future stent materials

Research output: Journal contributionsJournal articlesResearchpeer-review

Standard

New methods for in vivo degradation testing of future stent materials. / Bartosch, M.; Peters, Helge; Koerner, A. et al.
In: Materials and Corrosion, Vol. 69, No. 2, 01.02.2018, p. 156-166.

Research output: Journal contributionsJournal articlesResearchpeer-review

Harvard

Bartosch, M, Peters, H, Koerner, A, Schmitt, B, Berger, F, Hort, N & Witte, F 2018, 'New methods for in vivo degradation testing of future stent materials', Materials and Corrosion, vol. 69, no. 2, pp. 156-166. https://doi.org/10.1002/maco.201709521

APA

Bartosch, M., Peters, H., Koerner, A., Schmitt, B., Berger, F., Hort, N., & Witte, F. (2018). New methods for in vivo degradation testing of future stent materials. Materials and Corrosion, 69(2), 156-166. https://doi.org/10.1002/maco.201709521

Vancouver

Bartosch M, Peters H, Koerner A, Schmitt B, Berger F, Hort N et al. New methods for in vivo degradation testing of future stent materials. Materials and Corrosion. 2018 Feb 1;69(2):156-166. doi: 10.1002/maco.201709521

Bibtex

@article{28b22a358abc4f04a0c9690aac22a3f3,
title = "New methods for in vivo degradation testing of future stent materials",
abstract = "Selection of a degradable material for cardiovascular stent application is a difficult task. Beside various alloys, different processing routes, annealing and surface treatment options, and coatings are available. Unfortunately, the in vivo properties of materials cannot be reliably predicted in vitro. In order to narrow down the selection there is a great need for an easy and fast in vivo pre-selection method for possible stent materials. In this study we tested an approach presented by another group. It was compared to our new approach, the Carrier Stent. Here, several material samples are sewn on an inert, polymeric stent. It can be implanted in virtually every vessel of an animal model. It enables testing of different materials at the same location. Mg10Gd was chosen as an example for a degradable alloy for future stent applications. Wires were produced by drawing, annealed, etched, and analyzed. Due to the short wire lengths, a new clamping method for tensile tests was developed. Different heat treatments and etching processes were evaluated prior to the implantations. Both direct wire implantation and carrier stent implantation were performed and compared.",
keywords = "biodegradable stent, in vivo in vitro correlation, magnesium alloy, tensile test, wire, Engineering",
author = "M. Bartosch and Helge Peters and A. Koerner and B. Schmitt and F. Berger and Norbert Hort and F. Witte",
year = "2018",
month = feb,
day = "1",
doi = "10.1002/maco.201709521",
language = "English",
volume = "69",
pages = "156--166",
journal = "Materials and Corrosion",
issn = "0947-5117",
publisher = "John Wiley & Sons Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - New methods for in vivo degradation testing of future stent materials

AU - Bartosch, M.

AU - Peters, Helge

AU - Koerner, A.

AU - Schmitt, B.

AU - Berger, F.

AU - Hort, Norbert

AU - Witte, F.

PY - 2018/2/1

Y1 - 2018/2/1

N2 - Selection of a degradable material for cardiovascular stent application is a difficult task. Beside various alloys, different processing routes, annealing and surface treatment options, and coatings are available. Unfortunately, the in vivo properties of materials cannot be reliably predicted in vitro. In order to narrow down the selection there is a great need for an easy and fast in vivo pre-selection method for possible stent materials. In this study we tested an approach presented by another group. It was compared to our new approach, the Carrier Stent. Here, several material samples are sewn on an inert, polymeric stent. It can be implanted in virtually every vessel of an animal model. It enables testing of different materials at the same location. Mg10Gd was chosen as an example for a degradable alloy for future stent applications. Wires were produced by drawing, annealed, etched, and analyzed. Due to the short wire lengths, a new clamping method for tensile tests was developed. Different heat treatments and etching processes were evaluated prior to the implantations. Both direct wire implantation and carrier stent implantation were performed and compared.

AB - Selection of a degradable material for cardiovascular stent application is a difficult task. Beside various alloys, different processing routes, annealing and surface treatment options, and coatings are available. Unfortunately, the in vivo properties of materials cannot be reliably predicted in vitro. In order to narrow down the selection there is a great need for an easy and fast in vivo pre-selection method for possible stent materials. In this study we tested an approach presented by another group. It was compared to our new approach, the Carrier Stent. Here, several material samples are sewn on an inert, polymeric stent. It can be implanted in virtually every vessel of an animal model. It enables testing of different materials at the same location. Mg10Gd was chosen as an example for a degradable alloy for future stent applications. Wires were produced by drawing, annealed, etched, and analyzed. Due to the short wire lengths, a new clamping method for tensile tests was developed. Different heat treatments and etching processes were evaluated prior to the implantations. Both direct wire implantation and carrier stent implantation were performed and compared.

KW - biodegradable stent

KW - in vivo in vitro correlation

KW - magnesium alloy

KW - tensile test

KW - wire

KW - Engineering

UR - http://www.scopus.com/inward/record.url?scp=85021819737&partnerID=8YFLogxK

U2 - 10.1002/maco.201709521

DO - 10.1002/maco.201709521

M3 - Journal articles

AN - SCOPUS:85021819737

VL - 69

SP - 156

EP - 166

JO - Materials and Corrosion

JF - Materials and Corrosion

SN - 0947-5117

IS - 2

ER -

DOI