Influence of implant base material on secondary bone healing: an in silico study
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In: Computer Methods in Biomechanics and Biomedical Engineering, 13.04.2024.
Research output: Journal contributions › Journal articles › Research › peer-review
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TY - JOUR
T1 - Influence of implant base material on secondary bone healing
T2 - an in silico study
AU - Nayak, Gargi Shankar
AU - Roland, Michael
AU - Wiese, Björn
AU - Hort, Norbert
AU - Diebels, Stefan
N1 - Publisher Copyright: © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2024/4/13
Y1 - 2024/4/13
N2 - The implant material at the fracture site influences fracture healing not only from biological perspective but also from mechanical perspective. Biodegradable implants such as magnesium (Mg) based alloys have shown faster secondary bone healing properties as compared to bioinert implants such as titanium (Ti). The general reasoning behind this is the benefit of Mg from biocompatibility perspectives. We studied the effect of Ti and Mg as base materials for implants from mechanical perspectives, where we focused on the displacements at the fracture site of the tibia and their influence on the stimulus for bone healing. We found out that in comparison to Ti, Mg implants have minimal stress shielding problem, only which led to better mechanical stimulus at the fracture site.
AB - The implant material at the fracture site influences fracture healing not only from biological perspective but also from mechanical perspective. Biodegradable implants such as magnesium (Mg) based alloys have shown faster secondary bone healing properties as compared to bioinert implants such as titanium (Ti). The general reasoning behind this is the benefit of Mg from biocompatibility perspectives. We studied the effect of Ti and Mg as base materials for implants from mechanical perspectives, where we focused on the displacements at the fracture site of the tibia and their influence on the stimulus for bone healing. We found out that in comparison to Ti, Mg implants have minimal stress shielding problem, only which led to better mechanical stimulus at the fracture site.
KW - Bone remodelling
KW - in silico study, stress shielding
KW - Mg implants
KW - Engineering
UR - http://www.scopus.com/inward/record.url?scp=85190289931&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/253ddfc1-8ad3-3805-a057-f1f6d5ac541d/
U2 - 10.1080/10255842.2024.2338121
DO - 10.1080/10255842.2024.2338121
M3 - Journal articles
C2 - 38613482
AN - SCOPUS:85190289931
JO - Computer Methods in Biomechanics and Biomedical Engineering
JF - Computer Methods in Biomechanics and Biomedical Engineering
SN - 1025-5842
ER -