TY - JOUR

T1 - Fiber introduction mass spectrometry

T2 - Determination of pesticides in herbal infusions using a novel sol-gel PDMS/PVA fiber for solid-phase microextraction

AU - Da Silva, Rogério Cesar

AU - Zuin, Vânia Gomes

AU - Yariwake, Janete Harumi

AU - Eberlin, Marcos Nogueira

AU - Augusto, Fabio

PY - 2007/10

Y1 - 2007/10

N2 - An application of the direct coupling of solid-phase microextraction (SPME) with mass spectrometry (MS), a technique known AS fiber introduction mass spectrometry (FIMS), is described to determine organochlorine (OCP) and organophosphorus (OPP) pesticides in herbal infusions of Passiflora L. A new fiber coated with a composite of poly(dimethylsiloxane) and poly(vinyl alcohol) (PDMS/PVA) was used. Sensitive, selective, simple and simultaneous quantification of several OCP and OPP was achieved by monitoring diagnostic fragment ions of m/z 266 (chlorothalonil), m/z 195 (α-endosulfan), m/z 278 (fenthion), m/z 263 (methyl parathion) and m/z 173 (malathion). Simple headspace SPME extraction (25 min) and fast FIMS detection (less than 40 s) of OCP and OPP from a highly complex herbal matrix provided good linearity with correlation coefficients of 0.991-0.999 for concentrations ranging from 10 to 140 ng ml-1 of each compound. Good accuracy (80 to 110%), precision (0.6-14.9%) and low limits of detection (0.3-3.9 ng ml-1) were also obtained. Even after 400 desorption cycles inside the ionization source of the mass spectrometer, no visible degradation of the novel PDMS/PVA fiber was detected, confirming its suitability for FIMS. Fast (ca 20 s) pesticide desorption occurs for the PDMS/PVA fiber owing to the small thickness of the film and its reduced water sorption.

AB - An application of the direct coupling of solid-phase microextraction (SPME) with mass spectrometry (MS), a technique known AS fiber introduction mass spectrometry (FIMS), is described to determine organochlorine (OCP) and organophosphorus (OPP) pesticides in herbal infusions of Passiflora L. A new fiber coated with a composite of poly(dimethylsiloxane) and poly(vinyl alcohol) (PDMS/PVA) was used. Sensitive, selective, simple and simultaneous quantification of several OCP and OPP was achieved by monitoring diagnostic fragment ions of m/z 266 (chlorothalonil), m/z 195 (α-endosulfan), m/z 278 (fenthion), m/z 263 (methyl parathion) and m/z 173 (malathion). Simple headspace SPME extraction (25 min) and fast FIMS detection (less than 40 s) of OCP and OPP from a highly complex herbal matrix provided good linearity with correlation coefficients of 0.991-0.999 for concentrations ranging from 10 to 140 ng ml-1 of each compound. Good accuracy (80 to 110%), precision (0.6-14.9%) and low limits of detection (0.3-3.9 ng ml-1) were also obtained. Even after 400 desorption cycles inside the ionization source of the mass spectrometer, no visible degradation of the novel PDMS/PVA fiber was detected, confirming its suitability for FIMS. Fast (ca 20 s) pesticide desorption occurs for the PDMS/PVA fiber owing to the small thickness of the film and its reduced water sorption.

KW - Fiber introduction mass spectrometry (FIMS)

KW - Passiflora L. infusion

KW - PDMS/PVA fibers

KW - Pesticides

KW - Solid-phase microextraction (SPME)

KW - Chemistry

UR - http://www.scopus.com/inward/record.url?scp=35648985538&partnerID=8YFLogxK

U2 - 10.1002/jms.1323

DO - 10.1002/jms.1323

M3 - Journal articles

C2 - 17902108

AN - SCOPUS:35648985538

VL - 42

SP - 1358

EP - 1362

JO - Journal of Mass Spectrometry

JF - Journal of Mass Spectrometry

SN - 1076-5174

IS - 10

ER -