Degradable biomaterials based on magnesium corrosion
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In: Current Opinion in Solid State and Materials Science, Vol. 12, No. 5-6, 10.2008, p. 63-72.
Research output: Journal contributions › Journal articles › Research › peer-review
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TY - JOUR
T1 - Degradable biomaterials based on magnesium corrosion
AU - Witte, Frank
AU - Hort, Norbert
AU - Vogt, Carla
AU - Cohen, Smadar
AU - Kainer, Karl Ulrich
AU - Willumeit, Regine
AU - Feyerabend, Frank
PY - 2008/10
Y1 - 2008/10
N2 - Biodegradable metals are breaking the current paradigm in biomaterial science to develop only corrosion resistant metals. In particular, metals which consist of trace elements existing in the human body are promising candidates for temporary implant materials. These implants would be temporarily needed to provide mechanical support during the healing process of the injured or pathological tissue. Magnesium and its alloys have been investigated recently by many authors as a suitable biodegradable biomaterial. In this investigative review we would like to summarize the latest achievements and comment on the selection and use, test methods and the approaches to develop and produce magnesium alloys that are intended to perform clinically with an appropriate host response.
AB - Biodegradable metals are breaking the current paradigm in biomaterial science to develop only corrosion resistant metals. In particular, metals which consist of trace elements existing in the human body are promising candidates for temporary implant materials. These implants would be temporarily needed to provide mechanical support during the healing process of the injured or pathological tissue. Magnesium and its alloys have been investigated recently by many authors as a suitable biodegradable biomaterial. In this investigative review we would like to summarize the latest achievements and comment on the selection and use, test methods and the approaches to develop and produce magnesium alloys that are intended to perform clinically with an appropriate host response.
KW - Animal model
KW - Biodegradable
KW - Corrosion
KW - Implant
KW - In vitro
KW - In vivo
KW - Magnesium alloy
KW - Engineering
UR - http://www.scopus.com/inward/record.url?scp=65749107040&partnerID=8YFLogxK
U2 - 10.1016/j.cossms.2009.04.001
DO - 10.1016/j.cossms.2009.04.001
M3 - Journal articles
AN - SCOPUS:65749107040
VL - 12
SP - 63
EP - 72
JO - Current Opinion in Solid State and Materials Science
JF - Current Opinion in Solid State and Materials Science
SN - 1359-0286
IS - 5-6
ER -