Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis

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Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis. / Ekers, D.; Webster, L.; Van Straten, Annemieke et al.
In: PLoS ONE, Vol. 9, No. 6, e100100, 17.06.2014.

Research output: Journal contributionsJournal articlesResearchpeer-review

Harvard

Ekers, D, Webster, L, Van Straten, A, Cuijpers, P, Richards, D & Gilbody, S 2014, 'Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis', PLoS ONE, vol. 9, no. 6, e100100. https://doi.org/10.1371/journal.pone.0100100

APA

Ekers, D., Webster, L., Van Straten, A., Cuijpers, P., Richards, D., & Gilbody, S. (2014). Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis. PLoS ONE, 9(6), Article e100100. https://doi.org/10.1371/journal.pone.0100100

Vancouver

Ekers D, Webster L, Van Straten A, Cuijpers P, Richards D, Gilbody S. Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis. PLoS ONE. 2014 Jun 17;9(6):e100100. doi: 10.1371/journal.pone.0100100

Bibtex

@article{5fff0fc59afe44a685a7b7481b3229cf,
title = "Behavioural activation for depression: an update of meta-analysis of effectiveness and sub group analysis",
abstract = "BackgroundDepression is a common, disabling condition for which psychological treatments are recommended. Behavioural activation has attracted increased interest in recent years. It has been over 5 years since our meta-analyses summarised the evidence supporting and this systematic review updates those findings and examines moderators of treatment effect.MethodRandomised trials of behavioural activation for depression versus controls or anti-depressant medication were identified using electronic database searches, previous reviews and reference lists. Data on symptom level and study level moderators were extracted and analysed using meta-analysis, sub-group analysis and meta-regression respectively.ResultsTwenty six randomised controlled trials including 1524 subjects were included in this meta-analysis. A random effects meta-analysis of symptom level post treatment showed behavioural activation to be superior to controls (SMD −0.74 CI −0.91 to −0.56, k = 25, N = 1088) and medication (SMD −0.42 CI −0.83 to-0.00, k = 4, N = 283). Study quality was low in the majority of studies and follow- up time periods short. There was no indication of publication bias and subgroup analysis showed limited association between moderators and effect size.ConclusionsThe results in this meta-analysis support and strengthen the evidence base indicating Behavioural Activation is an effective treatment for depression. Further high quality research with longer term follow-up is needed to strengthen the evidence base.",
keywords = "Health sciences, Psychology",
author = "D. Ekers and L. Webster and {Van Straten}, Annemieke and Pim Cuijpers and D. Richards and S. Gilbody",
year = "2014",
month = jun,
day = "17",
doi = "10.1371/journal.pone.0100100",
language = "English",
volume = "9",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",

}

RIS

TY - JOUR

T1 - Behavioural activation for depression

T2 - an update of meta-analysis of effectiveness and sub group analysis

AU - Ekers, D.

AU - Webster, L.

AU - Van Straten, Annemieke

AU - Cuijpers, Pim

AU - Richards, D.

AU - Gilbody, S.

PY - 2014/6/17

Y1 - 2014/6/17

N2 - BackgroundDepression is a common, disabling condition for which psychological treatments are recommended. Behavioural activation has attracted increased interest in recent years. It has been over 5 years since our meta-analyses summarised the evidence supporting and this systematic review updates those findings and examines moderators of treatment effect.MethodRandomised trials of behavioural activation for depression versus controls or anti-depressant medication were identified using electronic database searches, previous reviews and reference lists. Data on symptom level and study level moderators were extracted and analysed using meta-analysis, sub-group analysis and meta-regression respectively.ResultsTwenty six randomised controlled trials including 1524 subjects were included in this meta-analysis. A random effects meta-analysis of symptom level post treatment showed behavioural activation to be superior to controls (SMD −0.74 CI −0.91 to −0.56, k = 25, N = 1088) and medication (SMD −0.42 CI −0.83 to-0.00, k = 4, N = 283). Study quality was low in the majority of studies and follow- up time periods short. There was no indication of publication bias and subgroup analysis showed limited association between moderators and effect size.ConclusionsThe results in this meta-analysis support and strengthen the evidence base indicating Behavioural Activation is an effective treatment for depression. Further high quality research with longer term follow-up is needed to strengthen the evidence base.

AB - BackgroundDepression is a common, disabling condition for which psychological treatments are recommended. Behavioural activation has attracted increased interest in recent years. It has been over 5 years since our meta-analyses summarised the evidence supporting and this systematic review updates those findings and examines moderators of treatment effect.MethodRandomised trials of behavioural activation for depression versus controls or anti-depressant medication were identified using electronic database searches, previous reviews and reference lists. Data on symptom level and study level moderators were extracted and analysed using meta-analysis, sub-group analysis and meta-regression respectively.ResultsTwenty six randomised controlled trials including 1524 subjects were included in this meta-analysis. A random effects meta-analysis of symptom level post treatment showed behavioural activation to be superior to controls (SMD −0.74 CI −0.91 to −0.56, k = 25, N = 1088) and medication (SMD −0.42 CI −0.83 to-0.00, k = 4, N = 283). Study quality was low in the majority of studies and follow- up time periods short. There was no indication of publication bias and subgroup analysis showed limited association between moderators and effect size.ConclusionsThe results in this meta-analysis support and strengthen the evidence base indicating Behavioural Activation is an effective treatment for depression. Further high quality research with longer term follow-up is needed to strengthen the evidence base.

KW - Health sciences

KW - Psychology

UR - http://www.scopus.com/inward/record.url?scp=84903288794&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/0e1fef9c-c8b6-366f-9761-a201396e3a9e/

U2 - 10.1371/journal.pone.0100100

DO - 10.1371/journal.pone.0100100

M3 - Journal articles

C2 - 24936656

VL - 9

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 6

M1 - e100100

ER -

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