Laboratory automation has become essential for the survival of laboratories in today’s market. The pursuit of efficiency among companies operating in the laboratory sector extends to encompass all analytical phases of processes. This study aims to provide a review of automation processes in clinical analysis laboratories. It is a literature review that included a search in the Lilacs, Scielo, and Scopus databases. Technological advances have enabled laboratories of various sizes and examination volumes to incorporate some level of automation into their processes. This is because manually performed steps require more execution time and are prone to errors. Automation emerges as a solution capable of enhancing the accuracy of analyses, resulting in greater operational efficiency for the laboratory. The key lies in choosing the best model based on the laboratory’s reality, aiming to reduce costs and increase the quality and objectivity of services, thereby adding more value to the customer.