1. //
  2. Start
  3. //
  4. Publikationen
  5. Therapeutic drug monitoring of posaconaz...
  6. Formate
  7. //

Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method

Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet

Standard

Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method. / Neubauer, Werner Christian; Engelhardt, Monika; König, Armin et al.
in: Antimicrobial Agents and Chemotherapy, Jahrgang 54, Nr. 9, 09.2010, S. 4029-4032.

Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet

Harvard

Neubauer, WC, Engelhardt, M, König, A, Hieke, S, Jung, M, Bertz, H & Kümmerer, K 2010, 'Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method', Antimicrobial Agents and Chemotherapy, Jg. 54, Nr. 9, S. 4029-4032. https://doi.org/10.1128/AAC.00150-10

APA

Neubauer, W. C., Engelhardt, M., König, A., Hieke, S., Jung, M., Bertz, H., & Kümmerer, K. (2010). Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method. Antimicrobial Agents and Chemotherapy, 54(9), 4029-4032. https://doi.org/10.1128/AAC.00150-10

Vancouver

Neubauer WC, Engelhardt M, König A, Hieke S, Jung M, Bertz H et al. Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method. Antimicrobial Agents and Chemotherapy. 2010 Sep;54(9):4029-4032. doi: 10.1128/AAC.00150-10

Bibtex

@article{ed6522367c874d37bc534e2f3584c839,
title = "Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method",
abstract = "Parallel administration of the proton pump inhibitor (PPI) esomeprazole has been shown to decrease oral bioavailability of posaconazole in healthy volunteers. We prospectively analyzed serum samples (n = 59) obtained from hematology patients (n = 27) under posaconazole prophylaxis. Patients treated concomitantly with pantoprazole had significantly lower posaconazole levels than patients without PPI treatment (median levels of 630 μg/liter versus 1,125 μg/liter, respectively). These results suggest that drug monitoring is relevant when posaconazole and pantoprazole are administered concomitantly. Copyright {\textcopyright} 2010, American Society for Microbiology. All Rights Reserved.",
keywords = "Chemistry, Adult, Aged, Antifungal Agents, Chromatography, High Pressure Liquid, Female, Hematologic Neoplasms, Humans, Male, Middle Aged, Mycoses, Prospective Studies, Triazoles",
author = "Neubauer, {Werner Christian} and Monika Engelhardt and Armin K{\"o}nig and Stefanie Hieke and Manfred Jung and Hartmut Bertz and Klaus K{\"u}mmerer",
year = "2010",
month = sep,
doi = "10.1128/AAC.00150-10",
language = "English",
volume = "54",
pages = "4029--4032",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "1098-6596",
publisher = "American Society For Microbiology",
number = "9",

}

RIS

TY - JOUR

T1 - Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method

AU - Neubauer, Werner Christian

AU - Engelhardt, Monika

AU - König, Armin

AU - Hieke, Stefanie

AU - Jung, Manfred

AU - Bertz, Hartmut

AU - Kümmerer, Klaus

PY - 2010/9

Y1 - 2010/9

N2 - Parallel administration of the proton pump inhibitor (PPI) esomeprazole has been shown to decrease oral bioavailability of posaconazole in healthy volunteers. We prospectively analyzed serum samples (n = 59) obtained from hematology patients (n = 27) under posaconazole prophylaxis. Patients treated concomitantly with pantoprazole had significantly lower posaconazole levels than patients without PPI treatment (median levels of 630 μg/liter versus 1,125 μg/liter, respectively). These results suggest that drug monitoring is relevant when posaconazole and pantoprazole are administered concomitantly. Copyright © 2010, American Society for Microbiology. All Rights Reserved.

AB - Parallel administration of the proton pump inhibitor (PPI) esomeprazole has been shown to decrease oral bioavailability of posaconazole in healthy volunteers. We prospectively analyzed serum samples (n = 59) obtained from hematology patients (n = 27) under posaconazole prophylaxis. Patients treated concomitantly with pantoprazole had significantly lower posaconazole levels than patients without PPI treatment (median levels of 630 μg/liter versus 1,125 μg/liter, respectively). These results suggest that drug monitoring is relevant when posaconazole and pantoprazole are administered concomitantly. Copyright © 2010, American Society for Microbiology. All Rights Reserved.

KW - Chemistry

KW - Adult

KW - Aged

KW - Antifungal Agents

KW - Chromatography, High Pressure Liquid

KW - Female

KW - Hematologic Neoplasms

KW - Humans

KW - Male

KW - Middle Aged

KW - Mycoses

KW - Prospective Studies

KW - Triazoles

UR - http://www.scopus.com/inward/record.url?scp=77956122820&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ddfbf767-8284-3f5d-99ee-36156fbeae27/

U2 - 10.1128/AAC.00150-10

DO - 10.1128/AAC.00150-10

M3 - Journal articles

C2 - 20547790

VL - 54

SP - 4029

EP - 4032

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 1098-6596

IS - 9

ER -

Weitere Publikationen dieser Person(en)

Accelerating the industrial transition with safe-and-sustainable-by-design (SSbD)

Soeteman-Hernández, L. G., Tickner, J. A., Dierckx, A., Kümmerer, K., Apel, C. & Strömberg, E., 17.02.2025, (Elektronische Veröffentlichung vor Drucklegung) in: RSC Sustainability. 7 S.

Publikation: Beiträge in Zeitschriften › Übersichtsarbeiten › Forschung

Eco-pharma dilemma: Navigating environmental sustainability trade-offs within the lifecycle of pharmaceuticals – A comment

Moermond, C. T. A., Puhlmann, N., Pieters, L., Matharu, A., Boone, L., Dobbelaere, M., Proquin, H., Kümmerer, K., Ragas, A. M. J., Vidaurre, R., Venhuis, B. & De Smedt, D., 01.02.2025, in: Sustainable Chemistry and Pharmacy. 43, 10 S., 101893.

Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet

Green chemistry and sustainable chemistry related to water challenges: Solutions and prospects in a changing climate

Mahjoub, B., Fersi, C., Bouteffeha, M. & Kümmerer, K., 01.04.2025, in: Current Opinion in Green and Sustainable Chemistry. 52, 11 S., 101000.

Publikation: Beiträge in Zeitschriften › Übersichtsarbeiten › Forschung

Inventing a secure future: material stewardship as chemistry's mission for sustainability

Matlin, S. A., Cornell, S. E., Kümmerer, K., Mahaffy, P. G. & Mehta, G., 14.01.2025, in: RSC Sustainability. 3, 2, S. 804-821 18 S., d4su00576g.

Publikation: Beiträge in Zeitschriften › Übersichtsarbeiten › Forschung

The complex spatio-temporal dynamics of organic micropollutants in tidal rivers

Schneider, J. R. L., Kümmerer, K., Logemann, J. & Radke, M., 01.03.2025, in: Chemosphere. 373, 10 S., 144180.

Publikation: Beiträge in Zeitschriften › Zeitschriftenaufsätze › Forschung › begutachtet

DOI

Zuletzt angesehen

Projekte

  1. Kooperative Lösungsansätze zur nachhaltigen Verminderung der Belastung von Oberflächengewässern mit Veterinärarzneimitteln im Einzugsgebiet der Talsperre Haltern
  2. Sozio-ökonomische Analyse von Pflegemaßnahmen zur Erhaltung von Offenlandschaften unter besonderer Berücksichtigung der Wirtschaftlichkeit und sozialen Akzeptanz
  3. Gezielte Einstellung gradierter Eigenschaften unter Nutzung der in-situ Hybridisierung zur Herstellung eigenschaftsoptimierter, thermoplastbasierter Faser-Metall Laminate
  4. Thermische Untergrundspeicher in Energiesystemen: Optimierung der Einbindung der Aquiferspeicher in die Wärme- und Kälteversorgung der Parlamentsbauten im Berliner Spreebogen
  5. Erforschung von Gelingensfaktoren für die Unterstützung von Kindertageseinrichtungen im Bereich Familienbildung, -beratung, -unterstützung am Beispiel des Modellprojektes „Piazza“
  6. Politische Diskurse über die Unternehmensbesteuerung in Deutschland. Eine vergleichende Netzwerkanalyse von Presseberichten und Parlamentsanhörungen zur Steuergesetzgebung seit 1965.

Aktivitäten

  1. Keynote speech entitled: "A Stabilizing Control Strategy for a Bank System using State Space and Sliding Mode Control Approach with an Extended Kalman Filter"
  2. Talk together with Benedikt Haus at the Regelungstechnisches Kolloquium in Boppard. Talk entitled: “Kalman Filter in der Anwendung”. March 4-6, 2020, Boppard, (Germany).
  3. Jahrestagung der Kommission Pädagogische Anthropologie der Sektion Allgemeine Erziehungswissenschaft der Deutschen Gesellschaft für Erziehungswissenschaft 2012
  4. Jahrestagung der Sektion Interkulturelle und International Vergleichende Erziehungswissenschaft der Deutschen Gesellschaft für Erziehungswissenschaft - DGfE 2015
  5. "Is your slam based on facts, or on gags and slapstick?”– How problems of contemporary science communication concepts become visible in new public genres like the science slam
  6. 4th Symposium on Sensorless Control for Electrical Drives & 2nd Symposium on Predictive Control of Electrical Drives and Power Electronics - SLED PROCEDE 2013 Joint Conference
  7. Plenary Speaker at the 2021 8th International Conference on Computing and Communication Technologies (WCCCT 2021) with a talk entitled: „A Real Application of Fuzzy Based Control Strategy for a Nonholonomic Car-Like Robot„, January 23-25, Dalian, China.

Publikationen

  1. Erleichtert Öffentlichkeitsbeteiligung die Umsetzung (umwelt-)politischer Maßnahmen? Ein Modellansatz zur Erklärung der Implementationseffektivität
  2. Förderung von Diagnose- und Interventionskompetenzen mithilfe von Praxisbezügen – Konzeption eines Seminars für die erste Phase der Lehrkräfteausbildung
  3. Lesestrategien zur Unterstützung des Verstehens von Textaufgaben. Vermittlung und Routinen im Mathematikunterricht aus Sicht von Lehrkräften und Lernenden
  4. Competence models for assessing individual learning outcomes and evaluating educational processes - a priority program of the German research foundation (DFG)
  5. Use of Machine-Learning Algorithms Based on Text, Audio and Video Data in the Prediction of Anxiety and Post-Traumatic Stress in General and Clinical Populations
  6. Korngrößenabhängigkeit der Verteilung ausgesuchter schwerflüchtiger organischer Substanzen in Flusssedimenten und Schlussfolgerungen für die Sedimentanalytik
  7. Effects of Soil Properties, Temperature and Disturbance on Diversity and Functional Composition of Plant Communities Along a Steep Elevational Gradient on Tenerife
  8. Reduced nitrate leaching from an Irish cropland soil under non-inversion tillage with cover cropping greatly outweighs increased dissolved organic nitrogen leaching
  9. Berechnung von Eisengehalten und Verockerungspotential von Schluckbrunnen mithilfe von Temperatur-, Redoxpotential-, pH-Wert-, Leitfähigkeits- und Sauerstoffsättigungsdaten
  10. Stenotypy and eurytopy - Distribution models as a tool for estimating niche overlap in two spider species, Trochosa terricola and Eresus kollari (Araneae: Lycosidae/Eresidae).
  11. Die Jahrgangsmischung auf dem Prüfstand: Effekte jahrgangsübergreifenden Lernens auf Kompetenzen und sozio-emotionales Wohlbefinden von Grundschülerinnen und Grundschülern
  12. Determination of the construction and the material identity values of outside building components with the help of in-situ measuring procedures and FEM-simulation calculations
  13. The Role of Linked Social-Ecological Systems in a Mobile Agent-Based Ecosystem Service from Giant Honey Bees (Apis dorsata) in an Indigenous Community Forest in Palawan, Philippines
  14. Neanderthals in changing environments from MIS 5 to early MIS 4 in northern Central Europe – Integrating archaeological, (chrono)stratigraphic and paleoenvironmental evidence at the site of Lichtenberg