TY - JOUR

T1 - Simultaneous determination of alkylphenol ethoxylates and their biotransformation products by liquid chromatography/electrospray ionisation tandem mass spectrometry

AU - Jahnke, Annika

AU - Gandraß, Jürgen

AU - Ruck, Wolfgang

PY - 2004/4/30

Y1 - 2004/4/30

N2 - Reversed-phase LC-MS/MS is used to determine major estrogenic alkylphenol ethoxylates (APEOs) and their biotransformation products. It allows the simultaneous analysis of eight APEOs, alkylphenoxy carboxylates (APECs) and alkylphenols (APs) in sewage treatment plant (STP) effluents in the same extract after solid-phase enrichment on polymeric Oasis HLB. As precursor ions, [APEO+NH4]+, [APEC-H]- and [AP-H]- were monitored. Instrumental limits of detection (LOD) were 2-600pg, corresponding to sample concentrations of 0.04-12ngl-1, without correction for overall method recoveries. Matrix-induced signal suppression during electrospray ionisation (ESI) and extraction as well as overall method recoveries were assessed and the suitability of deuterated surrogates as internal standards was evaluated. © 2004 Elsevier B.V. All rights reserved.

AB - Reversed-phase LC-MS/MS is used to determine major estrogenic alkylphenol ethoxylates (APEOs) and their biotransformation products. It allows the simultaneous analysis of eight APEOs, alkylphenoxy carboxylates (APECs) and alkylphenols (APs) in sewage treatment plant (STP) effluents in the same extract after solid-phase enrichment on polymeric Oasis HLB. As precursor ions, [APEO+NH4]+, [APEC-H]- and [AP-H]- were monitored. Instrumental limits of detection (LOD) were 2-600pg, corresponding to sample concentrations of 0.04-12ngl-1, without correction for overall method recoveries. Matrix-induced signal suppression during electrospray ionisation (ESI) and extraction as well as overall method recoveries were assessed and the suitability of deuterated surrogates as internal standards was evaluated. © 2004 Elsevier B.V. All rights reserved.

KW - Chemistry

KW - alkylphenol ethoxylates

KW - alkylphenoxy carboxylates

KW - nonylphenol

KW - octylphenol

KW - water analysis

KW - Alkylphenol ethoxylates

KW - Octylphenol

KW - Alkylphenoxy carboxylates

KW - Water analysis

KW - Nonylphenol

UR - http://www.scopus.com/inward/record.url?scp=1842451590&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ce74aa4f-aa01-3b93-963c-51f49c7c842b/

U2 - 10.1016/j.chroma.2004.02.060

DO - 10.1016/j.chroma.2004.02.060

M3 - Journal articles

VL - 1035

SP - 115

EP - 122

JO - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 0021-9673

IS - 1

ER -