TY - JOUR

T1 - Seasonal allergic rhinitis and antihistamine effects on children's learning

AU - Vuurman, Eric

AU - Van Veggel, Lieve

AU - Uiterwijk, Mir

AU - Leutner, Detlev

AU - O'Hanlon, James F.

PY - 1992/9/1

Y1 - 1992/9/1

N2 - Children suffering from seasonal allergic rhinitis (SAR) and matched normals were instructed on the use of a didactic computer simulation. Groups of SAR children received different treatments before instruction; i.e., sedating or nonsedating antihistamines or placebo. All returned after 2 weeks for an examination measuring factual and conceptual knowledge and the application of a learned strategy. Examination results showed large impairing effects of SAR on prior learning. That effect was modified by the drug treatment relative to placebo. Conclusion: SAR and sedating antihistamines combine to reduce children's learning ability.

AB - Children suffering from seasonal allergic rhinitis (SAR) and matched normals were instructed on the use of a didactic computer simulation. Groups of SAR children received different treatments before instruction; i.e., sedating or nonsedating antihistamines or placebo. All returned after 2 weeks for an examination measuring factual and conceptual knowledge and the application of a learned strategy. Examination results showed large impairing effects of SAR on prior learning. That effect was modified by the drug treatment relative to placebo. Conclusion: SAR and sedating antihistamines combine to reduce children's learning ability.

KW - Allergy

KW - Learning

KW - Lymphokines

KW - Sickness Behavior

KW - Psychology

UR - http://www.scopus.com/inward/record.url?scp=44049111596&partnerID=8YFLogxK

U2 - 10.1016/0924-977X(92)90101-D

DO - 10.1016/0924-977X(92)90101-D

M3 - Conference abstract in journal

AN - SCOPUS:44049111596

VL - 2

SP - 263

EP - 265

JO - European Neuropsychopharmacology

JF - European Neuropsychopharmacology

SN - 0924-977X

IS - 3

ER -