Entrepreneurship is one of the most effective means to alleviate poverty in developing countries. Effective entrepreneurship requires psychological approaches—in particular, active (i.e., agentic) approaches. We introduce an action-regulation training approach, focusing on self-regulation and active behavior in entrepreneurship as a bottom-up solution for poverty reduction. We present two different training interventions. The first focuses on enhancing personal initiative in entrepreneurs from developing countries. The second aims at boosting startup rates in these countries by enhancing participants’ entrepreneurial skills and motivation. We describe underlying theoretical assumptions, structures, and effects of both training interventions and discuss evaluation studies with randomized pretest-posttest control-group designs showing that action-regulation training is a successful means to promote entrepreneurship in developing countries.